Spontaneous splenic rupture in an acute leukemia patient with splenic tuberculosis: A case report

  • Authors:
    • Yue Zhang
    • Juan Zhang
    • Tingting Chen
    • Hui Zeng
    • Bing Zhao
    • Yong Zhang
    • Xiaohuan Zhou
    • Wei Han
    • Yanping Hu
    • Fengge Liu
    • Zhijuan Shan
    • Weifeng Gao
    • Hebing Zhou
  • View Affiliations

  • Published online on: Wednesday, December 28, 2016
  • Pages:209-213 DOI: 10.3892/mco.2016.1120
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Abstract

Spontaneous splenic rupture, also referred to as atraumatic splenic rupture, is a rare but life‑threatening emergency condition. Without timely diagnosis and treatment, the mortality rate of splenic rupture approaches 100%. The etiology of atraumatic splenic rupture varies; it is reportedly associated with neoplasms or splenic infection, but is rarely encountered in patients with both conditions. We herein report the case of a 58‑year‑old male patient with acute myeloid leukemia (AML) complicated by splenic tuberculosis (TB), who presented with spontaneous rupture of the spleen. Pathological examination of the resected spleen revealed multifocal granulomatosis with caseous necrosis. However, with timely diagnosis and surgical intervention, the patient recovered successfully and is currently on consolidation therapy. To the best of our knowledge, this is the first case of spontaneous splenic rupture in AML with splenic TB. The relevant literature on spontaneous splenic rupture was also reviewed and the potential etiology and treatment were discussed.

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February 2017
Volume 6 Issue 2

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Copy and paste a formatted citation
APA
Zhang, Y., Zhang, J., Chen, T., Zeng, H., Zhao, B., Zhang, Y. ... Zhou, H. (2017). Spontaneous splenic rupture in an acute leukemia patient with splenic tuberculosis: A case report. Molecular and Clinical Oncology, 6, 209-213. http://dx.doi.org/10.3892/mco.2016.1120
MLA
Zhang, Y., Zhang, J., Chen, T., Zeng, H., Zhao, B., Zhang, Y., Zhou, X., Han, W., Hu, Y., Liu, F., Shan, Z., Gao, W., Zhou, H."Spontaneous splenic rupture in an acute leukemia patient with splenic tuberculosis: A case report". Molecular and Clinical Oncology 6.2 (2017): 209-213.
Chicago
Zhang, Y., Zhang, J., Chen, T., Zeng, H., Zhao, B., Zhang, Y., Zhou, X., Han, W., Hu, Y., Liu, F., Shan, Z., Gao, W., Zhou, H."Spontaneous splenic rupture in an acute leukemia patient with splenic tuberculosis: A case report". Molecular and Clinical Oncology 6, no. 2 (2017): 209-213. http://dx.doi.org/10.3892/mco.2016.1120