Molecular Mechanisms and Protective Effects of Natural Agents in Skin Disorders

Human skin is an organ plays an important roles in protecting us against external challenges such as ultraviolet (UV) radiation, bacteria, virus, toxic chemicals, and pollutants. These factors can weaken the structure and biological function of skin results in skin aging and pathological skin disorders. In addition, loss of subcutaneous fat by excess exposure to UV rays considered as a crucial cause of metabolic diseases. Therefore, multidisciplinary and combinational approach is essentially needed to develop anti-skin disorder agents. Natural agents including their single constituents (flavonoids, phenolic compounds, and isoflavone etc) have received much attention as a potential candidate for developing safe new drug. Actually, numerous studies have showed the many natural agents which have biological activities against skin disorders and the molecular mechanisms on how they regulate the molecular cascades involved in skin homeostasis have been elucidated. This special issue aim to provide the latest innovative research on functional study of natural agents in skin disorders and it will cover the research topics such as 1. photoaging, 2. oxidative stress on skin, 3. skin regeneration and skim stem cells, 4. skin cancer, 5. skin microbiome, 6. skin inflammation, 7. Immunological disorders in skin.

04/07/2025