1
|
Maas S, Patt S, Schrey M and Rich A:
Underediting of glutamate receptor GluR-B mRNA in malignant
gliomas. Proc Natl Acad Sci USA. 98:14687–14692. 2001. View Article : Google Scholar : PubMed/NCBI
|
2
|
Cenci C, Barzotti R, Galeano F, Corbelli
S, Rota R, Massimi L, Di Rocco C, O'Connell MA and Gallo A:
Down-regulation of RNA editing in pediatric astrocytomas: ADAR2
editing activity inhibits cell migration and proliferation. J Biol
Chem. 283:7251–7260. 2008. View Article : Google Scholar : PubMed/NCBI
|
3
|
Li Z, Tian Y, Tian N, Zhao X, Du C, Han L
and Zhang H: Aberrant alternative splicing pattern of ADAR2
downregulates adenosine-to-inosine editing in glioma. Oncol Rep.
33:2845–2852. 2015.PubMed/NCBI
|
4
|
Benne R, Van Den Burg J, Brakenhoff JP,
Sloof P, Van Boom JH and Tromp MC: Major transcript of the
frameshifted coxll gene from trypanosome mitochondria contains four
nucleotides that are not encoded in the DNA. Cell. 46:819–826.
1986. View Article : Google Scholar : PubMed/NCBI
|
5
|
Rebagliati MR and Melton DA: Antisense RNA
injections in fertilized frog eggs reveal an RNA duplex unwinding
activity. Cell. 48:599–605. 1987. View Article : Google Scholar : PubMed/NCBI
|
6
|
Wagner RW, Smith JE, Cooperman BS and
Nishikura K: A double-stranded RNA unwinding activity introduces
structural alterations by means of adenosine to inosine conversions
in mammalian cells and Xenopus eggs. Proc Natl Acad Sci USA.
86:2647–2651. 1989. View Article : Google Scholar : PubMed/NCBI
|
7
|
Tang W, Fei Y and Page M: Biological
significance of RNA editing in cells. Mol Biotechnol. 52:91–100.
2012. View Article : Google Scholar : PubMed/NCBI
|
8
|
Osato D, Rogers K, Guo Q, Li F, Richmond
G, Klug F and Simpson L: Uridine insertion/deletion RNA editing in
trypanosomatid mitochondria: In search of the editosome. RNA.
15:1338–1344. 2009. View Article : Google Scholar : PubMed/NCBI
|
9
|
Visomirski-Robic LM and Gott JM:
Insertional editing in isolated Physarum mitochondria is linked to
RNA synthesis. RNA. 3:821–837. 1997.PubMed/NCBI
|
10
|
Doe CM, Relkovic D, Garfield AS, Dalley
JW, Theobald DE, Humby T, Wilkinson LS and Isles AR: Loss of the
imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing
and altered 5HT2CR-mediated behaviour. Hum Mol Genet. 18:2140–2148.
2009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Klipcan L, Moor N, Kessler N and Safro MG:
Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA
synthetases catalyze the charging of tRNA with the meta-tyrosine.
Proc Natl Acad Sci USA. 106:11045–11048. 2009. View Article : Google Scholar : PubMed/NCBI
|
12
|
Lynch M, Koskella B and Schaack S:
Mutation pressure and the evolution of organelle genomic
architecture. Science. 311:1727–1730. 2006. View Article : Google Scholar : PubMed/NCBI
|
13
|
Sommer B, Kohler M, Sprengel R and Seeburg
PH: RNA editing in brain controls a determinant of ion flow in
glutamate-gated channels. Cell. 67:11–19. 1991. View Article : Google Scholar : PubMed/NCBI
|
14
|
Nishikura K: Functions and regulation of
RNA editing by ADAR deaminases. Annu Rev Biochem. 79:321–349. 2010.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Bazak L, Haviv A, Barak M, Jacob-Hirsch J,
Deng P, Zhang R, Isaacs FJ, Rechavi G, Li JB, Eisenberg E and
Levanon EY: A-to-I RNA editing occurs at over a hundred million
genomic sites, located in a majority of human genes. Genome Res.
24:365–376. 2014. View Article : Google Scholar : PubMed/NCBI
|
16
|
Macbeth MR, Schubert HL, Vandemark AP,
Lingam AT, Hill CP and Bass BL: Inositol hexakisphosphate is bound
in the ADAR2 core and required for RNA editing. Science.
309:1534–1539. 2005. View Article : Google Scholar : PubMed/NCBI
|
17
|
Ryter JM and Schultz SC: Molecular basis
of double-stranded RNA-protein interactions: Structure of a
dsRNA-binding domain complexed with dsRNA. EMBO J. 17:7505–7513.
1998. View Article : Google Scholar : PubMed/NCBI
|
18
|
Kuttan A and Bass BL: Mechanistic insights
into editing-site specificity of ADARs. Proc Natl Acad Sci USA.
109:E3295–E3304. 2012. View Article : Google Scholar : PubMed/NCBI
|
19
|
Slotkin W and Nishikura K:
Adenosine-to-inosine RNA editing and human disease. Genome Med.
5:1052013. View
Article : Google Scholar : PubMed/NCBI
|
20
|
Chen CX, Cho DS, Wang Q, Lai F, Carter KC
and Nishikura K: A third member of the RNA-specific adenosine
deaminase gene family, ADAR3, contains both single- and
double-stranded RNA binding domains. RNA. 6:755–767. 2000.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Levanon EY, Eisenberg E, Yelin R, Nemzer
S, Hallegger M, Shemesh R, Fligelman ZY, Shoshan A, Pollock SR,
Sztybel D, et al: Systematic identification of abundant A-to-I
editing sites in the human transcriptome. Nat Biotechnol.
22:1001–1005. 2004. View
Article : Google Scholar : PubMed/NCBI
|
22
|
Collingridge GL, Olsen RW, Peters J and
Spedding M: A nomenclature for ligand-gated ion channels.
Neuropharmacology. 56:2–5. 2009. View Article : Google Scholar : PubMed/NCBI
|
23
|
Higuchi MSF, Köhler M, Sommer B, Sprengel
R and Seeburg PH: RNA editing of AMPA receptor subunit GluR-B: A
basepaired intron-exon structure determines position and
efficiency. Cell. 75:1361–1370. 1993. View Article : Google Scholar : PubMed/NCBI
|
24
|
Barresi S, Tomaselli S, Athanasiadis A,
Galeano F, Locatelli F, Bertini E, Zanni G and Gallo A:
Oligophrenin-1 (OPHN1), a gene involved in X-linked intellectual
disability, undergoes RNA editing and alternative splicing during
human brain development. PLoS One. 9:e913512014. View Article : Google Scholar : PubMed/NCBI
|
25
|
Hogg M, Paro S, Keegan LP and O'Connell
MA: RNA editing by mammalian ADARs. Adv Genet. 73:87–120. 2011.
View Article : Google Scholar : PubMed/NCBI
|
26
|
Yang W, Chendrimada TP, Wang Q, Higuchi M,
Seeburg PH, Shiekhattar R and Nishikura K: Modulation of microRNA
processing and expression through RNA editing by ADAR deaminases.
Nat Struct Mol Biol. 13:13–21. 2006. View
Article : Google Scholar : PubMed/NCBI
|
27
|
Vesely C, Tauber S, Sedlazeck FJ, Tajaddod
M, Haeseler AV and Jantsch MF: ADAR2 induces reproducible changes
in sequence and abundance of mature microRNAs in the mouse brain.
Nucleic Acids Res. 42:12155–12168. 2014. View Article : Google Scholar : PubMed/NCBI
|
28
|
Yang Y, Zhou X and Jin Y: ADAR-mediated
RNA editing in non-coding RNA sequences. Sci China Life Sci.
56:944–952. 2013. View Article : Google Scholar : PubMed/NCBI
|
29
|
Hundley HA and Bass BL: ADAR editing in
double-stranded UTRs and other noncoding RNA sequences. Trends
Biochem Sci. 35:377–383. 2010. View Article : Google Scholar : PubMed/NCBI
|
30
|
Berget SM, Moore C and Sharp PA: Spliced
segments at the 5′ terminus of adenovirus 2 late mRNA. Proc Natl
Acad Sci USA. 74:3171–3175. 1977. View Article : Google Scholar : PubMed/NCBI
|
31
|
Sambrook J: Adenovirus amazes at Cold
Spring Harbor. Nature. 268:101–104. 1977. View Article : Google Scholar : PubMed/NCBI
|
32
|
Gilbert W: Why genes in pieces? Nature.
271:5011978. View
Article : Google Scholar : PubMed/NCBI
|
33
|
Brett D, Pospisil H, Valcarcel J, Reich J
and Bork P: Alternative splicing and genome complexity. Nat Genet.
30:29–30. 2002. View
Article : Google Scholar : PubMed/NCBI
|
34
|
Sharp PA: Split genes and RNA splicing.
Cell. 77:805–815. 1994. View Article : Google Scholar : PubMed/NCBI
|
35
|
Lander ES, Linton LM, Birren B, Nusbaum C,
Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, et al:
Initial sequencing and analysis of the human genome. Nature.
409:860–921. 2001. View
Article : Google Scholar : PubMed/NCBI
|
36
|
Sharp PA: The discovery of split genes and
RNA splicing. Trends Biochem Sci. 30:279–281. 2005. View Article : Google Scholar : PubMed/NCBI
|
37
|
Wang ET, Sandberg R, Luo S, Khrebtukova I,
Zhang L, Mayr C, Kingsmore SF, Schroth GP and Burge CB: Alternative
isoform regulation in human tissue transcriptomes. Nature.
456:470–476. 2008. View Article : Google Scholar : PubMed/NCBI
|
38
|
Pan Q, Shai O, Lee LJ, Frey BJ and
Blencowe BJ: Deep surveying of alternative splicing complexity in
the human transcriptome by high-throughput sequencing. Nat Genet.
40:1413–1415. 2008. View
Article : Google Scholar : PubMed/NCBI
|
39
|
Venables JP: Aberrant and alternative
splicing in cancer. Cancer Res. 64:7647–7654. 2004. View Article : Google Scholar : PubMed/NCBI
|
40
|
Tomaselli S, Bonamassa B, Alisi A, Nobili
V, Locatelli F and Gallo A: ADAR enzyme and miRNA story: A
nucleotide that can make the difference. Int J Mol Sci.
14:22796–22816. 2013. View Article : Google Scholar : PubMed/NCBI
|
41
|
Mittaz L, Scott HS, Rossier C, Seeburg PH,
Higuchi M and Antonarakis SE: Cloning of a human RNA editing
deaminase (ADARB1) of glutamate receptors that maps to chromosome
21q22.3. Genomics. 41:210–217. 1997. View Article : Google Scholar : PubMed/NCBI
|
42
|
Slavov D and Gardiner K: Phylogenetic
comparison of the pre-mRNA adenosine deaminase ADAR2 genes and
transcripts: Conservation and diversity in editing site sequence
and alternative splicing patterns. Gene. 299:83–94. 2002.
View Article : Google Scholar : PubMed/NCBI
|
43
|
Kawahara Y, Ito K, Ito M, Tsuji S and Kwak
S: Novel splice variants of human ADAR2 mRNA: Skipping of the exon
encoding the dsRNA-binding domains and multiple C-terminal splice
sites. Gene. 363:193–201. 2005. View Article : Google Scholar : PubMed/NCBI
|
44
|
Gerber A, O'Connell MA and Keller W: Two
forms of human double-stranded RNA-specific editase 1 (hRED1)
generated by the insertion of an Alu cassette. RNA. 3:453–463.
1997.PubMed/NCBI
|
45
|
Lai F, Chen CX, Carter KC and Nishikura K:
Editing of glutamate receptor B subunit ion channel RNAs by four
alternatively spliced DRADA2 double-stranded RNA adenosine
deaminases. Mol Cell Biol. 17:2413–2424. 1997. View Article : Google Scholar : PubMed/NCBI
|
46
|
Rueter SM, Dawson TR and Emeson RB:
Regulation of alternative splicing by RNA editing. Nature.
399:75–80. 1999. View
Article : Google Scholar : PubMed/NCBI
|
47
|
Maas S and Gommans WM: Novel exon of
mammalian ADAR2 extends open reading frame. PLoS One. 4:e42252009.
View Article : Google Scholar : PubMed/NCBI
|
48
|
Agranat L, Sperling J and Sperling R: A
novel tissue-specific alternatively spliced form of the A-to-I RNA
editing enzyme ADAR2. RNA Biol. 7:253–262. 2010. View Article : Google Scholar : PubMed/NCBI
|
49
|
Solomon O, Oren S, Safran M, Deshet-Unger
N, Akiva P, Jacob-Hirsch J, Cesarkas K, Kabesa R, Amariglio N,
Unger R, et al: Global regulation of alternative splicing by
adenosine deaminase acting on RNA (ADAR). RNA. 19:591–604. 2013.
View Article : Google Scholar : PubMed/NCBI
|
50
|
Galeano F, Tomaselli S, Locatelli F and
Gallo A: A-to-I RNA editing: The ‘ADAR’ side of human cancer. Semin
Cell Dev Biol. 23:244–250. 2012. View Article : Google Scholar : PubMed/NCBI
|
51
|
Dominissini D, Moshitch-Moshkovitz S,
Amariglio N and Rechavi G: Adenosine-to-inosine RNA editing meets
cancer. Carcinogenesis. 32:1569–1577. 2011. View Article : Google Scholar : PubMed/NCBI
|
52
|
Tomaselli S, Galeano F, Massimi L, Di
Rocco C, Lauriola L, Mastronuzzi A, Locatelli F and Gallo A: ADAR2
editing activity in newly diagnosed versus relapsed pediatric
high-grade astrocytomas. BMC Cancer. 13:2552013. View Article : Google Scholar : PubMed/NCBI
|
53
|
Choudhury Y, Tay FC, Lam DH, Sandanaraj E,
Tang C, Ang BT and Wang S: Attenuated adenosine-to-inosine editing
of microRNA-376a* promotes invasiveness of glioblastoma cells. J
Clin Invest. 122:4059–4076. 2012. View Article : Google Scholar : PubMed/NCBI
|
54
|
Galeano F, Rossetti C, Tomaselli S,
Cifaldi L, Lezzerini M, Pezzullo M, Boldrini R, Massimi L, Di Rocco
CM, Locatelli F and Gallo A: ADAR2-editing activity inhibits
glioblastoma growth through the modulation of the
CDC14B/Skp2/p21/p27 axis. Oncogene. 32:998–1009. 2013. View Article : Google Scholar : PubMed/NCBI
|
55
|
Wei J, Li ZH, Du C, Qi B, Zhao X, Wang L,
Bi L, Wang G, Zhang X, Su X, et al: Abnormal expression of an ADAR2
alternative splicing variant in gliomas downregulates
adenosine-to-inosine RNA editing. Acta Neurochir (Wien).
156:1135–1142. 2014. View Article : Google Scholar : PubMed/NCBI
|
56
|
Hideyama T and Kwak S: When Does ALS
Start? ADAR2-GluA2 Hypothesis for the Etiology of Sporadic ALS.
Front Mol Neurosci. 4:332011. View Article : Google Scholar : PubMed/NCBI
|