Radiotherapy and wound healing: Principles, management and prospects (Review)

  • Authors:
    • Matthias Gieringer
    • Jan Gosepath
    • Ramin Naim
  • View Affiliations

  • Published online on: May 25, 2011     https://doi.org/10.3892/or.2011.1319
  • Pages:299-307
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Abstract

Radiation therapy is a major therapeutic modality in the management of cancer patients. Over 60% of these patients receive radiotherapy at some point during their course of treatment and over 90% will develop skin reactions after therapy. Problematic wound healing in radiation-damaged tissue constitutes a major surgical difficulty and despite all efforts, irradiated skin remains a therapeutic challenge. This review provides an overview of the fundamental principles of radiation therapy with regards to the wound healing in normal and irradiated skin. Furthermore, it presents techniques that describe how to prevent and manage skin side effects as well as prospects that may improve cutaneous wound repair in general and in irradiated skin.

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August 2011
Volume 26 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

2016 Impact Factor: 2.662
Ranked #31/217 Oncology
(total number of cites)

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APA
Gieringer, M., Gosepath, J., & Naim, R. (2011). Radiotherapy and wound healing: Principles, management and prospects (Review). Oncology Reports, 26, 299-307. https://doi.org/10.3892/or.2011.1319
MLA
Gieringer, M., Gosepath, J., Naim, R."Radiotherapy and wound healing: Principles, management and prospects (Review)". Oncology Reports 26.2 (2011): 299-307.
Chicago
Gieringer, M., Gosepath, J., Naim, R."Radiotherapy and wound healing: Principles, management and prospects (Review)". Oncology Reports 26, no. 2 (2011): 299-307. https://doi.org/10.3892/or.2011.1319