A comparison of human G-Csf and human Gm-Csf given concurrently with anti-cancer chemotherapy
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- Published online on: September 1, 2002 https://doi.org/10.3892/or.9.5.945
- Pages: 945-950
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Abstract
Granulocyte-colony-stimulating factor (G-Csf) and granulocyte-macrophagecolony-stimulating factor (GM-Csf) were each given concurrently with continuous infusion of doxorubicin, ifosphamide, or vinorelbine. Both cytokines enabled the dose intensity of these three anti-tumor agents to be substantially increased without an increase in drug toxicity. The effect of Gm-Csf as a stimulant of dendritic cell production and function was noted.
