1.
|
Mountzios G, Dimopoulos MA, Bamias A,
Papadopoulos G, Kastritis E, Syrigos K, Pavlakis G and Terpos E:
Abnormal bone remodeling process is due to an imbalance in the
receptor activator of nuclear factor-kappa B ligand
(RANKL)/osteoprotegerin (OPG) axis in patients with solid tumors
metastatic to the skeleton. Acta Oncol. 46:221–229. 2007.
View Article : Google Scholar
|
2.
|
Fohr B, Dunstan CR and Seibel MJ: Clinical
review 165: markers of bone remodeling in metastatic bone disease.
J Clin Endocrinol Metab. 88:5059–5075. 2003. View Article : Google Scholar : PubMed/NCBI
|
3.
|
Maurer J, Harris MM, Stanford VA, Lohman
TG, Cussler E, Going SB and Houtkooper LB: Dietary iron positively
influences bone mineral density in postmenopausal women on hormone
replacement therapy. J Nutr. 135:863–869. 2005.PubMed/NCBI
|
4.
|
Schnitzler CM, Schnaid E, MacPhail AP,
Mesquita JM and Robson HJ: Ascorbic acid deficiency, iron overload
and alcohol abuse underlie the severe osteoporosis in black African
patients with hip fractures - a bone histomorphometric study.
Calcified Tissue Int. 76:79–89. 2005. View Article : Google Scholar : PubMed/NCBI
|
5.
|
Valenti L, Varenna M, Fracanzani A, Rossi
V, Fargion S and Sinigaglia L: Association between iron overload
and osteoporosis in patients with hereditary hemochromatosis.
Osteoporosis Int. 20:549–555. 2009. View Article : Google Scholar : PubMed/NCBI
|
6.
|
Liu G, Men P, Kenner GH and Miller SC:
Age-associated iron accumulation in bone: implications for
postmenopausal osteoporosis and a new target for prevention and
treatment by chelation. Biometals. 19:245–251. 2006. View Article : Google Scholar : PubMed/NCBI
|
7.
|
Tsay J, Yang Z, Ross FP,
Cunningham-Rundles S, Lin H, Coleman R, Mayer-Kuckuk P, Doty SB,
Grady RW, Giardina PJ, Boskey AL and Vogiatzi MG: Bone loss caused
by iron overload in a murine model: importance of oxidative stress.
Blood. 116:2582–2589. 2010. View Article : Google Scholar : PubMed/NCBI
|
8.
|
Yamasaki K and Hagiwara H: Excess iron
inhibits osteoblast metabolism. Toxicol Lett. 191:211–215. 2009.
View Article : Google Scholar : PubMed/NCBI
|
9.
|
Messer JG, Kilbarger AK, Erikson KM and
Kipp DE: Iron overload alters iron-regulatory genes and proteins,
down-regulates osteoblastic phenotype, and is associated with
apoptosis in fetal rat calvaria cultures. Bone. 45:972–979. 2009.
View Article : Google Scholar : PubMed/NCBI
|
10.
|
Yang Q, Jian J, Abramson SB and Huang X:
Inhibitory effects of iron on bone morphogenetic protein 2-induced
osteoblastogenesis. J Bone Miner Res. 26:1188–1196. 2011.
View Article : Google Scholar : PubMed/NCBI
|
11.
|
Ishii KA, Fumoto T, Iwai K, Takeshita S,
Ito M, Shimohata N, Aburatani H, Taketani S, Lelliott CJ,
Vidal-Puig A and Ikeda K: Coordination of PGC-1beta and iron uptake
in mitochondrial biogenesis and osteoclast activation. Nat Med.
15:259–266. 2009. View
Article : Google Scholar : PubMed/NCBI
|
12.
|
Galaris D and Pantopoulos K: Oxidative
stress and iron homeostasis: mechanistic and health aspects. Crit
Rev Clin Lab Sci. 45:1–23. 2008. View Article : Google Scholar : PubMed/NCBI
|
13.
|
Andrews M and Arredondo M: Hepatic and
adipocyte cells respond differentially to iron overload, hypoxic
and inflammatory challenge. Biometals. 25:749–759. 2012. View Article : Google Scholar : PubMed/NCBI
|
14.
|
Lean JM, Davies JT, Fuller K, Jagger CJ,
Kirstein B, Partington GA, Urry ZL and Chambers TJ: A crucial role
for thiol antioxidants in estrogen-deficiency bone loss. J Clin
Invest. 112:915–923. 2003. View Article : Google Scholar : PubMed/NCBI
|
15.
|
Jagger CJ, Lean JM, Davies JT and Chambers
TJ: Tumor necrosis factor-alpha mediates osteopenia caused by
depletion of antioxidants. Endocrinology. 146:113–118. 2005.
View Article : Google Scholar : PubMed/NCBI
|
16.
|
Fuller K, Murphy C, Kirstein B, Fox SW and
Chambers TJ: TNFalpha potently activates osteoclasts, through a
direct action independent of and strongly synergistic with RANKL.
Endocrinology. 143:1108–1118. 2002.PubMed/NCBI
|
17.
|
Lam J, Takeshita S, Barker JE, Kanagawa O,
Ross FP and Teitelbaum SL: TNF-alpha induces osteoclastogenesis by
direct stimulation of macrophages exposed to permissive levels of
RANK ligand. J Clin Invest. 106:1481–1488. 2000. View Article : Google Scholar : PubMed/NCBI
|
18.
|
Mattila P, Knuuttila M, Kovanen V and
Svanberg M: Improved bone biomechanical properties in rats after
oral xylitol administration. Calcif Tissue Int. 64:340–344. 1999.
View Article : Google Scholar : PubMed/NCBI
|
19.
|
Zhang L, Liu Y, Wang D, Zhao X, Qiu Z, Ji
H and Rong H: Bone biomechanical and histomorphometrical investment
in type 2 diabetic Goto-Kakizaki rats. Acta Diabetol. 46:119–126.
2009. View Article : Google Scholar : PubMed/NCBI
|
20.
|
Niu YB, Li YH, Kong XH, Zhang R, Sun Y, Li
Q, Li C, Liu L, Wang J and Mei QB: The beneficial effect of Radix
Dipsaci total saponins on bone metabolism in vitro and in vivo and
the possible mechanisms of action. Osteoporos Int. Apr 26–2012,
(Epub ahead of print). View Article : Google Scholar
|
21.
|
Rubin C, Turner AS, Mallinckrodt C, Jerome
C, McLeod K and Bain S: Mechanical strain, induced noninvasively in
the high-frequency domain, is anabolic to cancellous bone, but not
cortical bone. Bone. 30:445–452. 2002. View Article : Google Scholar : PubMed/NCBI
|
22.
|
Blair HC and Zaidi M: Osteoclastic
differentiation and function regulated by old and new pathways. Rev
Endocr Metab Disord. 7:23–32. 2006. View Article : Google Scholar : PubMed/NCBI
|
23.
|
Zhao B, Grimes SN, Li S, Hu X and Ivashkiv
LB: TNF-induced osteoclastogenesis and inflammatory bone resorption
are inhibited by transcription factor RBP-J. J Exp Med.
209:319–334. 2012. View Article : Google Scholar : PubMed/NCBI
|
24.
|
Vattakuzhi Y, Abraham SM, Freidin A, Clark
AR and Horwood NJ: Dual specificity phosphatase 1 null mice exhibit
spontaneous osteolytic disease and enhanced inflammatory osteolysis
in experimental arthritis. Arthritis Rheum. 64:2201–2210. 2012.
View Article : Google Scholar
|