Plasma exchange in small intestinal transplantation between ABO‑incompatible individuals: A case report

Zhang,Qiuhui; Hu,Xingbin; Xia,Aijun; Yi,Jing; An,Qunxing; Zhang,Xianqing

doi:10.3892/br.2013.177

Plasma exchange in small intestinal transplantation between ABO‑incompatible individuals: A case report

Authors:
- Qiuhui Zhang
- Xingbin Hu
- Aijun Xia
- Jing Yi
- Qunxing An
- Xianqing Zhang
View Affiliations

Affiliations: Department of Blood Transfusion, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, P.R. China
Published online on: September 27, 2013 https://doi.org/10.3892/br.2013.177
Pages: 39-40

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

The aim of this study was to investigate the application of plasma exchange in small intestinal transplantation between ABO blood type‑incompatible patients. A small intestinal transplantation case between ABO‑incompatible individuals is hereby presented and analyzed. The main treatment included plasma exchange, splenectomy and immunosuppression. The patient undergoing small intestinal transplantation exhibited stable vital signs. A mild acute rejection reaction developed ~2 weeks after the surgery, which the patient successfully overcame. The subsequent colonoscopy and pathological examination revealed no signs of acute rejection. In conclusion, plasma exchange in combination with anti‑immune rejection therapy proved to be an effective scheme for the management of small intestinal transplantation between ABO‑incompatible patients.

View Figures

View References

1	Cicalese L, Sileri P, Asolati M, et al: Infectious complications following living-related small bowel transplantation in adults. Transplant Proc. 33:1554–1555. 2001. View Article : Google Scholar : PubMed/NCBI
2	Abu-Elmagd K, Todo S, Tzakis A, et al: Three years clinical experience with intestinal transplantation. J Am Coll Surg. 179:385–400. 1994.PubMed/NCBI
3	Middleton SJ and Jamieson NV: The current status of small bowel transplantation in the UK and internationally. Gut. 54:1650–1657. 2005. View Article : Google Scholar : PubMed/NCBI
4	Ziring D, Tran R, Edelstein S, et al: Infectious enteritis after intestinal transplantation: incidence, timing, and outcome. Transplantation. 79:702–709. 2005. View Article : Google Scholar : PubMed/NCBI
5	Morioka D, togo S, Kumamoto T, et al: Six consecutive cases of successful adult ABO-incompatible living donor liver transplantation: a proposal of grading the severity of antibody-mediated rejection. Transplantation. 85:171–178. 2008. View Article : Google Scholar
6	Reyes J, Tzakis A, Todo S, et al: Nutritional management of intestinal transplant recipients. Transplant Proc. 25:1200–1201. 1993.PubMed/NCBI
7	Rostaing L, Massari P, Garcia VD, et al: Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study. Clin J Am Soc Nephrol. 6:430–439. 2011. View Article : Google Scholar : PubMed/NCBI
8	Kato T, Tzakis AG, Selvaggi G, et al: Transplantation of the spleen: effect of splenic allograft in human multivisceral transplantation. Ann Surg. 246:436–444. 2007. View Article : Google Scholar : PubMed/NCBI
9	Green M, Reyes J, Jabbour N, et al: Use of quantitative PCR to predict onset of Epstein-Barr viral infection and post- transplant lymphoproliferative disease after intestinal transplantation in children. Transplant Proc. 28:2759–2760. 1996.
10	Takahashi H, Kato T, Selvaggi G, et al: Subclinical rejection in the initial postoperative period in small intestinal transplantation: a negative influence on graft survival. Transplantation. 84:689–696. 2007. View Article : Google Scholar