|
1
|
de Lange T: Shelterin: The protein complex
that shapes and safeguards human telomeres. Genes Dev.
19:2100–2110. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Stewart SA, Ben-Porath I, Carey VJ,
O'Connor BF, Hahn WC and Weinberg RA: Erosion of the telomeric
single-strand overhang at replicative senescence. Nat Genet.
33:492–496. 2003. View
Article : Google Scholar : PubMed/NCBI
|
|
3
|
Maser RS and DePinho RA: Connecting
chromosomes, crisis, and cancer. Science. 297:565–569. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Tang T, Zhou FX, Lei H, Yu HJ, Xie CH,
Zhou YF and Liu SQ: Increased expression of telomere-related
proteins correlates with resistance to radiation in human laryngeal
cancer cell lines. Oncol Rep. 21:1505–1509. 2009.PubMed/NCBI
|
|
5
|
Zhou FX, Xiong J, Luo ZG, Dai J, Yu HJ,
Liao ZK, Lei H, Xie CH and Zhou YF: cDNA expression analysis of a
human radiosensitive-radioresistant cell line model identifies
telomere function as a hallmark of radioresistance. Radiat Res.
174:550–557. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lei M, Podell ER and Cech TR: Structure of
human POT1 bound to telomeric single-stranded DNA provides a model
for chromosome end-protection. Nat Struct Mol Biol. 11:1223–1229.
2004. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Colgin LM, Baran K, Baumann P, Cech TR and
Reddel RR: Human POT1 facilitates telomere elongation by
telomerase. Curr Biol. 13:942–946. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wu L, Multani AS, He H, Cosme-Blanco W,
Deng Y, Deng JM, Bachilo O, Pathak S, Tahara H, Bailey SM, et al:
Pot1 deficiency initiates DNA damage checkpoint activation and
aberrant homologous recombination at telomeres. Cell. 126:49–62.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Cawthon RM: Telomere length measurement by
a novel monochrome multiplex quantitative PCR method. Nucleic Acid
Res. 37:e212009. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Opresko PL, Mason PA, Podell ER, Lei M,
Hickson ID, Cech TR and Bohr VA: POT1 stimulates RecQ helicases WRN
and BLM to unwind telomeric DNA substrates. J Biol Chem.
280:32069–32080. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Baumann P, Podell E and Cech TR: Human
Pot1 (protection of telomeres) protein: Cytolocalization, gene
structure, and alternative splicing. Mol Cell Biol. 22:8079–8087.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Sedelnikova OA, Horikawa I, Zimonjic DB,
Popescu NC, Bonner WM and Barrett JC: Senescing human cells and
ageing mice accumulate DNA lesions with unrepairable double-strand
breaks. Nat Cell Biol. 6:168–170. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Michishita E, Park JY, Burneskis JM,
Barrett JC and Horikawa I: Evolutionarily conserved and
nonconserved cellular localizations and functions of human SIRT
proteins. Mol Biol Cell. 16:4623–4635. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Baumann P and Cech TR: Pot1, the putative
telomere end-binding protein in fission yeast and humans. Science.
292:1171–1175. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Churikov D, Wei C and Price CM: Vertebrate
POT1 restricts G-overhang length and prevents activation of a
telomeric DNA damage checkpoint but is dispensable for overhang
protection. Mol Cell Biol. 26:6971–6982. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Rangarajan A and Weinberg RA: Opinion:
Comparative biology of mouse versus human cells: modelling human
cancer in mice. Nat Rev Cancer. 3:952–959. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Wu X, Amos CI, Zhu Y, Zhao H, Grossman BH,
Shay JW, Luo S, Hong WK and Spitz MR: Telomere dysfunction: A
potential cancer predisposition factor. J Natl Cancer Inst.
95:1211–1218. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Widmann TA, Herrmann M, Taha N, Konig J
and Pfreundschuh M: Short telomeres in aggressive non-Hodgkin's
lymphoma as a risk factor in lymphomagenesis. Exp Hematol.
35:939–946. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ohali A, Avigad S, Ash S, Goshen Y, Luria
D, Feinmesser M, Zaizov R and Yaniv I: Telomere length is a
prognostic factor in neuroblastoma. Cancer. 107:1391–1399. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Hakin-Smith V, Jellinek DA, Levy D,
Carroll T, Teo M, Timperley WR, McKay MJ, Reddel RR and Royds JA:
Alternative lengthening of telomeres and survival in patients with
glioblastoma multiforme. Lancet. 361:836–838. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Avigad S, Naumov I, Ohali A, Jeison M,
Berco GH, Mardoukh J, Stark B, Ash S, Cohen IJ, Meller I, et al:
Short telomeres: A novel potential predictor of relapse in Ewing
sarcoma. Clin Cancer Res. 13:5777–5783. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Shen J, Terry MB, Gurvich I, Liao Y, Senie
RT and Santella RM: Short telomere length and breast cancer risk: A
study in sister sets. Cancer Res. 67:5538–5544. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Halaschek-Wiener J, Vulto I, Fornika D,
Collins J, Connors JM, Le ND, Lansdorp PM and Brooks-Wilson A:
Reduced telomere length variation in healthy oldest old. Mech
Ageing Dev. 129:638–641. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Gertler R, Rosenberg R, Stricker D,
Friederichs J, Hoos A, Werner M, Ulm K, Holzmann B, Nekarda H and
Siewert JR: Telomere length and human telomerase reverse
transcriptase expression as markers for progression and prognosis
of colorectal carcinoma. J Clin Oncol. 22:1807–1814. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Hackett JA and Greider CW: Balancing
instability: Dual roles for telomerase and telomere dysfunction in
tumorigenesis. Oncogene. 21:619–626. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Greider CW: Telomere length regulation.
Annu Rev Biochem. 65:337–365. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Doksani Y and de Lange T: The role of
double-strand break repair pathways at functional and dysfunctional
telomeres. Cold Spring Harb Perspect Biol. 6:a0165762014.
View Article : Google Scholar : PubMed/NCBI
|
