MicroRNAs: Novel regulatory molecules in acute lung injury/acute respiratory distress syndrome (Review)

  • Authors:
    • Yongmei Cao
    • Yi Lyu
    • Jiahua Tang
    • Yingchuan Li
  • View Affiliations

  • Published online on: March 1, 2016     https://doi.org/10.3892/br.2016.620
  • Pages: 523-527
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Abstract

Acute lung injury (ALI) and the more severe acute respiratory distress syndrome (ARDS) are common and complex inflammatory lung diseases. MicroRNAs (miRNAs), a type of non-coding RNA molecule that regulate gene expression at the post-transcriptional level, have emerged as a novel class of gene regulators, which have critical roles in a wide range of human disorders and diseases, including ALI. Certain types of miRNAs are abnormally expressed in response to lung injury. miRNAs can regulate inflammation pathways by targeting specific molecules and modulate immune response in the process of lung injury and repair. The regulation of miRNA can relieve injury response and promote the recovery of ALI/ARDS. Therefore, miRNAs may serve as novel therapeutic targets in ALI/ARDS.
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May-2016
Volume 4 Issue 5

Print ISSN: 2049-9434
Online ISSN:2049-9442

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Copy and paste a formatted citation
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Spandidos Publications style
Cao Y, Lyu Y, Tang J and Li Y: MicroRNAs: Novel regulatory molecules in acute lung injury/acute respiratory distress syndrome (Review). Biomed Rep 4: 523-527, 2016.
APA
Cao, Y., Lyu, Y., Tang, J., & Li, Y. (2016). MicroRNAs: Novel regulatory molecules in acute lung injury/acute respiratory distress syndrome (Review). Biomedical Reports, 4, 523-527. https://doi.org/10.3892/br.2016.620
MLA
Cao, Y., Lyu, Y., Tang, J., Li, Y."MicroRNAs: Novel regulatory molecules in acute lung injury/acute respiratory distress syndrome (Review)". Biomedical Reports 4.5 (2016): 523-527.
Chicago
Cao, Y., Lyu, Y., Tang, J., Li, Y."MicroRNAs: Novel regulatory molecules in acute lung injury/acute respiratory distress syndrome (Review)". Biomedical Reports 4, no. 5 (2016): 523-527. https://doi.org/10.3892/br.2016.620