1
|
Windler E, Schöffauer M and Zyriax BC: The
significance of low HDL-cholesterol levels in an ageing society at
increased risk for cardiovascular disease. Diab Vasc Dis Res.
4:136–142. 2007. View Article : Google Scholar : PubMed/NCBI
|
2
|
Chapman MJ, Ginsberg HN, Amarenco P,
Andreotti F, Borén J, Catapano AL, Descamps OS, Fisher E, Kovanen
PT, Kuivenhoven JA, et al: European Atherosclerosis Society
Consensus Panel: Triglyceride-rich lipoproteins and high-density
lipoprotein cholesterol in patients at high risk of cardiovascular
disease: Evidence and guidance for management. Eur Heart J.
32:1345–1361. 2011. View Article : Google Scholar : PubMed/NCBI
|
3
|
Thompson GR: Management of dyslipidaemia.
Heart. 90:949–955. 2004. View Article : Google Scholar : PubMed/NCBI
|
4
|
Ramjee V, Sperling LS and Jacobson TA:
Non-high-density lipoprotein cholesterol versus apolipoprotein B in
cardiovascular risk stratification: Do the math. J Am Coll Cardiol.
58:457–463. 2011. View Article : Google Scholar : PubMed/NCBI
|
5
|
Laitinen DL and Manthena S: Impact of
change in high-density lipoprotein cholesterol from baseline on
risk for major cardiovascular events. Adv Ther. 27:233–244. 2010.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Ali K Mahdy, Wonnerth A, Huber K and Wojta
J: Cardiovascular disease risk reduction by raising HDL cholesterol
- current therapies and future opportunities. Br J Pharmacol.
167:1177–1194. 2012. View Article : Google Scholar : PubMed/NCBI
|
7
|
Burillo E, Andres EM, Mateo-Gallego R,
Fiddyment S, Jarauta E, Cenarro A and Civeira F: High-density
lipoprotein cholesterol increase and non-cardiovascular mortality:
A meta-analysis. Heart. 96:1345–1351. 2010. View Article : Google Scholar : PubMed/NCBI
|
8
|
Liu JP, Tang Y, Zhou S, Toh BH, McLean C
and Li H: Cholesterol involvement in the pathogenesis of
neurodegenerative diseases. Mol Cell Neurosci. 43:33–42. 2010.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Scolari F and Ravani P: Atheroembolic
renal disease. Lancet. 375:1650–1660. 2010. View Article : Google Scholar : PubMed/NCBI
|
10
|
Foody JM, Wang Y, Kiefe CI, Ellerbeck EF,
Gold J, Radford MJ and Krumholz HM: Long-term prognostic importance
of total cholesterol in elderly survivors of an acute myocardial
infarction: The Cooperative Cardiovascular Pilot Project. J Am
Geriatr Soc. 51:930–936. 2003. View Article : Google Scholar : PubMed/NCBI
|
11
|
Peake KB and Vance JE: Defective
cholesterol trafficking in Niemann-Pick C-deficient cells. FEBS
Lett. 584:2731–2739. 2010. View Article : Google Scholar : PubMed/NCBI
|
12
|
Bi X and Liao G: Cholesterol in
Niemann-Pick Type C disease. Subcell Biochem. 51:319–335. 2010.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Rosenbaum AI and Maxfield FR: Niemann-Pick
type C disease: Molecular mechanisms and potential therapeutic
approaches. J Neurochem. 116:789–795. 2011. View Article : Google Scholar : PubMed/NCBI
|
14
|
Frolov A, Zielinski SE, Crowley JR,
Dudley-Rucker N, Schaffer JE and Ory DS: NPC1 and NPC2 regulate
cellular cholesterol homeostasis through generation of low density
lipoprotein cholesterol-derived oxysterols. J Biol Chem.
278:25517–25525. 2003. View Article : Google Scholar : PubMed/NCBI
|
15
|
Morris JA, Zhang D, Coleman KG, Nagle J,
Pentchev PG and Carstea ED: The genomic organization and
polymorphism analysis of the human Niemann-Pick C1 gene. Biochem
Biophys Res Commun. 261:493–498. 1999. View Article : Google Scholar : PubMed/NCBI
|
16
|
Carstea ED, Morris JA, Coleman KG, Loftus
SK, Zhang D, Cummings C, Gu J, Rosenfeld MA, Pavan WJ, Krizman DB,
et al: Niemann-Pick C1 disease gene: Homology to mediators of
cholesterol homeostasis. Science. 277:228–231. 1997. View Article : Google Scholar : PubMed/NCBI
|
17
|
Lecerf JM and de Lorgeril M: Dietary
cholesterol: From physiology to cardiovascular risk. Br J Nutr.
106:6–14. 2011. View Article : Google Scholar : PubMed/NCBI
|
18
|
Karten B, Peake KB and Vance JE:
Mechanisms and consequences of impaired lipid trafficking in
Niemann-Pick type C1-deficient mammalian cells. Biochim Biophys
Acta. 1791:659–670. 2009. View Article : Google Scholar : PubMed/NCBI
|
19
|
Scott C and Ioannou YA: The NPC1 protein:
Structure implies function. Biochim Biophys Acta. 1685:8–13. 2004.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Boadu E and Francis GA: The role of
vesicular transport in ABCA1-dependent lipid efflux and its
connection with NPC pathways. J Mol Med (Berl). 84:266–275. 2006.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Ye D, Lammers B, Zhao Y, Meurs I, Van
Berkel TJ and Van Eck M: ATP-binding cassette transporters A1 and
G1, HDL metabolism, cholesterol efflux, and inflammation: Important
targets for the treatment of atherosclerosis. Curr Drug Targets.
12:647–660. 2011. View Article : Google Scholar : PubMed/NCBI
|
22
|
Toth PP: Should we target HDL cholesterol
level in lowering cardiovascular risk? Pol Arch Med Wewn.
119:667–672. 2009.PubMed/NCBI
|
23
|
Iatan I, Alrasadi K, Ruel I, Alwaili K and
Genest J: Effect of ABCA1 mutations on risk for myocardial
infarction. Curr Atheroscler Rep. 10:413–426. 2008. View Article : Google Scholar : PubMed/NCBI
|
24
|
Anand SS: Quantifying effect of statins on
low density lipoprotein cholesterol, ischaemic heart disease, and
stroke: systematic review and meta-analysis. Law MR, Wald NJ,
Rudnicka AR. BMJ 2003; 326: 1407–408. Vasc Med. 8:289–290. 2003.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Després JP, Lemieux I, Dagenais GR, Cantin
B and Lamarche B: HDL-cholesterol as a marker of coronary heart
disease risk: The Québec cardiovascular study. Atherosclerosis.
153:263–272. 2000. View Article : Google Scholar : PubMed/NCBI
|
26
|
Feng B and Tabas I: ABCA1-mediated
cholesterol efflux is defective in free cholesterol-loaded
macrophages. Mechanism involves enhanced ABCA1 degradation in a
process requiring full NPC1 activity. J Biol Chem. 277:43271–43280.
2002. View Article : Google Scholar : PubMed/NCBI
|
27
|
Abela GS: Cholesterol crystals piercing
the arterial plaque and intima trigger local and systemic
inflammation. J Clin Lipidol. 4:156–164. 2010. View Article : Google Scholar : PubMed/NCBI
|
28
|
Ma W, Xu J, Wang Q, Xin Y, Zhang L, Zheng
X, Wang H, Sun K, Hui R and Huang X: Interaction of functional NPC1
gene polymorphism with smoking on coronary heart disease. BMC Med
Genet. 11:1492010. View Article : Google Scholar : PubMed/NCBI
|
29
|
Rodríguez-Rodríguez E, Vázquez-Higuera JL,
Sánchez-Juan P, Mateo I, Pozueta A, Martínez-García A, Frank A,
Valdivieso F, Berciano J, Bullido MJ, et al: Epistasis between
intracellular cholesterol trafficking-related genes (NPC1 and
ABCA1) and Alzheimer's disease risk. J Alzheimers Dis. 21:619–625.
2010.PubMed/NCBI
|
30
|
Sandholt CH, Vestmar MA, Bille DS,
Borglykke A, Almind K, Hansen L, Sandbæk A, Lauritzen T, Witte D,
Jørgensen T, et al: Studies of metabolic phenotypic correlates of
15 obesity associated gene variants. PLoS One. 6:e235312011.
View Article : Google Scholar : PubMed/NCBI
|
31
|
Hashemi M, Moazeni-Roodi AK, Fazaeli A,
Sandoughi M, Bardestani GR, Kordi-Tamandani DM and Ghavami S: Lack
of association between paraoxonase-1 Q192R polymorphism and
rheumatoid arthritis in southeast Iran. Genet Mol Res. 9:333–339.
2010. View Article : Google Scholar : PubMed/NCBI
|
32
|
Erickson RP, Larson-Thomé K, Weberg L,
Szybinska A, Mossakowska M, Styczynska M, Barcikowska M and
Kuznicki J: Variation in NPC1, the gene encoding Niemann-Pick C1, a
protein involved in intracellular cholesterol transport, is
associated with Alzheimer disease and/or aging in the Polish
population. Neurosci Lett. 447:153–157. 2008. View Article : Google Scholar : PubMed/NCBI
|
33
|
Ikonen E and Hölttä-Vuori M: Cellular
pathology of Niemann-Pick type C disease. Semin Cell Dev Biol.
15:445–454. 2004. View Article : Google Scholar : PubMed/NCBI
|
34
|
Oram JF and Vaughan AM: ATP-Binding
cassette cholesterol transporters and cardiovascular disease. Circ
Res. 99:1031–1043. 2006. View Article : Google Scholar : PubMed/NCBI
|
35
|
Tang C and Oram JF: The cell cholesterol
exporter ABCA1 as a protector from cardiovascular disease and
diabetes. Biochim Biophys Acta. 1791:563–572. 2009. View Article : Google Scholar : PubMed/NCBI
|
36
|
Shioji K, Nishioka J, Naraba H, Kokubo Y,
Mannami T, Inamoto N, Kamide K, Takiuchi S, Yoshii M, Miwa Y, et
al: A promoter variant of the ATP-binding cassette transporter A1
gene alters the HDL cholesterol level in the general Japanese
population. J Hum Genet. 49:141–147. 2004. View Article : Google Scholar : PubMed/NCBI
|
37
|
Wu L, Xi B, Zhang M, Shen Y, Zhao X, Cheng
H, Hou D, Sun D, Ott J, Wang X, et al: Associations of six single
nucleotide polymorphisms in obesity-related genes with BMI and risk
of obesity in Chinese children. Diabetes. 59:3085–3089. 2010.
View Article : Google Scholar : PubMed/NCBI
|
38
|
Schmitz G and Grandl M: Lipid homeostasis
in macrophages-implications for atherosclerosis. Rev Physiol
Biochem Pharmacol. 160:93–125. 2008.PubMed/NCBI
|
39
|
Cao XL, Yin RX, Wu DF, Miao L, Aung LH, Hu
XJ, Li Q, Yan TT, Lin WX and Pan SL: Genetic variant of V825I in
the ATP-binding cassette transporter A1 gene and serum lipid levels
in the Guangxi Bai Ku Yao and Han populations. Lipids Health Dis.
10:142011. View Article : Google Scholar : PubMed/NCBI
|
40
|
Xie C, Richardson JA, Turley SD and
Dietschy JM: Cholesterol substrate pools and steroid hormone levels
are normal in the face of mutational inactivation of NPC1 protein.
J Lipid Res. 47:953–963. 2006. View Article : Google Scholar : PubMed/NCBI
|
41
|
Yu X, Li X, Zhao G, Xiao J, Mo Z, Yin K,
Jiang Z, Fu Y, Zha X and Tang C: OxLDL up-regulates Niemann-Pick
type C1 expression through ERK1/2/COX-2/PPARα-signaling pathway in
macrophages. Acta Biochim Biophys Sin (Shanghai). 44:119–128. 2012.
View Article : Google Scholar : PubMed/NCBI
|
42
|
Zhang JR, Coleman T, Langmade SJ, Scherrer
DE, Lane L, Lanier MH, Feng C, Sands MS, Schaffer JE, Semenkovich
CF, et al: Niemann-Pick C1 protects against atherosclerosis in mice
via regulation of macrophage intracellular cholesterol trafficking.
J Clin Invest. 118:2281–2290. 2008.PubMed/NCBI
|
43
|
Kruth HS: Lipoprotein cholesterol and
atherosclerosis. Curr Mol Med. 1:633–653. 2001. View Article : Google Scholar : PubMed/NCBI
|
44
|
Lundberg AM and Yan ZQ: Innate immune
recognition receptors and damage-associated molecular patterns in
plaque inflammation. Curr Opin Lipidol. 22:343–349. 2011.
View Article : Google Scholar : PubMed/NCBI
|
45
|
Adamson S and Leitinger N: Phenotypic
modulation of macrophages in response to plaque lipids. Curr Opin
Lipidol. 22:335–342. 2011. View Article : Google Scholar : PubMed/NCBI
|
46
|
Ory DS: The niemann-pick disease genes;
regulators of cellular cholesterol homeostasis. Trends Cardiovasc
Med. 14:66–72. 2004. View Article : Google Scholar : PubMed/NCBI
|
47
|
Blanchette-Mackie EJ: Intracellular
cholesterol trafficking: Role of the NPC1 protein. Biochim Biophys
Acta. 1486:171–183. 2000. View Article : Google Scholar : PubMed/NCBI
|