1
|
Sun L, Wang Q, Chen B, Zhao Y, Shen B,
Wang H, Xu J, Zhu M, Zhao X, Xu C, et al: Gastric cancer
mesenchymal stem cells derived IL-8 induces PD-L1 expression in
gastric cancer cells via STAT3/mTOR-c-Myc signal axis. Cell Death
Dis. 9(928)2018.PubMed/NCBI View Article : Google Scholar
|
2
|
Potrc S, Ivanecz A, Krebs B, Marolt U,
Iljevec B and Jagric T: Outcomes of the surgical treatment for
adenocarcinoma of the cardia-single institution experience. Radiol
Oncol. 52:65–74. 2018.PubMed/NCBI View Article : Google Scholar
|
3
|
Xin J, Wu Y, Wang X, Li S, Chu H, Wang M,
Du M and Zhang Z: A transcriptomic study for identifying cardia-
and non-cardia-specific gastric cancer prognostic factors using
genetic algorithm-based methods. J Cell Mol Med. 24:9457–9465.
2020.PubMed/NCBI View Article : Google Scholar
|
4
|
Nguyen TH, Mallepally N, Hammad T, Liu Y,
Thrift AP, El-Serag HB and Tan MC: Prevalence of Helicobacter
pylori positive non-cardia gastric adenocarcinoma is low and
decreasing in a US population. Dig Dis Sci. 65:2403–2411.
2020.PubMed/NCBI
|
5
|
Zhang X, Bai Z, Chen B, Feng J, Yan F,
Jiang Z, Zhong Y, Wu J, Cheng L, Lu Z, et al: Polymorphism of
methylenetetrahydrofolate reductase gene is associated with
response to fluorouracil-based chemotherapy in Chinese patients
with gastric cancer. Chin Med J (Engl). 127:3562–3567.
2014.PubMed/NCBI
|
6
|
Bray F, Ren JS, Masuyer E and Ferlay J:
Global estimates of cancer prevalence for 27 sites in the adult
population in 2008. Int J Cancer. 132:1133–1145. 2013.PubMed/NCBI View Article : Google Scholar
|
7
|
Wang W, Sun Z, Deng JY, Qi XL, Feng XY,
Fang C, Ma XH, Wang ZN, Liang H, Xu HM and Zhou ZW: A novel
nomogram individually predicting disease-specific survival after D2
gastrectomy for advanced gastric cancer. Cancer Commun (Lond).
38(23)2018.PubMed/NCBI View Article : Google Scholar
|
8
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015.PubMed/NCBI View Article : Google Scholar
|
9
|
Zhang XM, Zhong R, Liu L, Wang Y, Yuan JX,
Wang P, Sun C, Zhang Z, Song WG and Miao XP: Smoking and COX-2
functional polymorphisms interact to increase the risk of gastric
cardia adenocarcinoma in Chinese population. PLoS One.
6(e21894)2011.PubMed/NCBI View Article : Google Scholar
|
10
|
Selhub J: Homocysteine metabolism. Ann Rev
Nutri. 19:217–246. 1999.PubMed/NCBI View Article : Google Scholar
|
11
|
Luo Z, Lu Z, Muhammad I, Chen Y, Chen Q,
Zhang J and Song Y: Associations of the MTHFR rs1801133
polymorphism with coronary artery disease and lipid levels: A
systematic review and updated meta-analysis. Lipids Health Dis.
17(191)2018.PubMed/NCBI View Article : Google Scholar
|
12
|
Jamshidi M, Mohammadi Pour S and
Mahmoudian-Sani MR: Single nucleotide variants associated with
colorectal cancer among Iranian patients: A narrative review.
Pharmgenomics Pers Med. 13:167–180. 2020.PubMed/NCBI View Article : Google Scholar
|
13
|
Ozen F, Sen M and Ozdemir O:
Methylenetetrahydrofolate reductase gene germ-line C677T and A1298C
SNPs are associated with colorectal cancer risk in the Turkish
population. Asian Pac J Cancer Prev. 15:7731–7735. 2014.PubMed/NCBI View Article : Google Scholar
|
14
|
Zhou X, Shan L, Na J, Li Y and Wang J: The
SNP rs4846048 of MTHFR enhances the cervical cancer risk through
association with miR-522: A preliminary report. Mol Genet Genomic
Med. 8(e1055)2020.PubMed/NCBI View Article : Google Scholar
|
15
|
De Marchi P, Melendez ME, Laus AC,
Kuhlmann PA, de Carvalho AC, Arantes LMRB, Evangelista AF, Andrade
ES, de Castro G Junior, Reis RM, et al: The role of
single-nucleotide polymorphism (SNPs) in toxicity of induction
chemotherapy based on cisplatin and paclitaxel in patients with
advanced head and neck cancer. Oral Oncol. 98:48–52.
2019.PubMed/NCBI View Article : Google Scholar
|
16
|
Hardi H, Melki R, Boughaleb Z, El Harroudi
T, Aissaoui S and Boukhatem N: Significant association between
ERCC2 and MTHR polymorphisms and breast cancer susceptibility in
Moroccan population: Genotype and haplotype analysis in a
case-control study. BMC Cancer. 18(292)2018.PubMed/NCBI View Article : Google Scholar
|
17
|
Xiong Y, Bian C, Lin X, Wang X, Xu K and
Zhao X: Methylenetetrahydrofolate reductase gene polymorphisms in
the risk of polycystic ovary syndrome and ovarian cancer. Biosci
Rep. 40(BSR20200995)2020.PubMed/NCBI View Article : Google Scholar
|
18
|
Floris M, Sanna D, Castiglia P, Putzu C,
Sanna V, Pazzola A, De Miglio MR, Sanges F, Pira G, Azara A, et al:
MTHFR, XRCC1 and OGG1 genetic polymorphisms in breast cancer: A
case-control study in a population from North Sardinia. BMC Cancer.
20(234)2020.PubMed/NCBI View Article : Google Scholar
|
19
|
Le Marchand L, Wilkens LR, Kolonel LN and
Henderson BE: The MTHFR C677T polymorphism and colorectal cancer:
The multiethnic cohort study. Cancer Epidemiol Biomarkers Prev.
14:1198–1203. 2005.PubMed/NCBI View Article : Google Scholar
|
20
|
Slattery ML, Potter JD, Samowitz W,
Schaffer D and Leppert M: Methylenetetrahydrofolate reductase,
diet, and risk of colon cancer. Cancer Epidemiol Biomarkers Prev.
8:513–518. 1999.PubMed/NCBI
|
21
|
Tang C, Yu S, Jiang H, Li W, Xu X, Cheng
X, Peng K, Chen E, Cui Y and Liu T: A meta-analysis:
Methylenetetrahydrofolate reductase C677T polymorphism in gastric
cancer patients treated with 5-Fu based chemotherapy predicts
serious hematologic toxicity but not prognosis. J Cancer.
9:1057–1066. 2018.PubMed/NCBI View Article : Google Scholar
|
22
|
Zhang S, Lin J, Jiang J, Chen Y, Tang W
and Liu L: Association between methylenetetrahydrofolate reductase
tagging polymorphisms and susceptibility of hepatocellular
carcinoma: A case-control study. Biosci Rep.
39(BSR20192517)2019.PubMed/NCBI View Article : Google Scholar
|
23
|
World Medical Association (WMA): WMA
Declaration of Helsinki - Ethical Principles for Medical Research
Involving Human Subjects. WMA, Ferney-Voltaire, 2018. urihttp://https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/simplehttps://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/.
Accessed July 9, 2018.
|
24
|
Rohlfs RV and Weir BS: Distributions of
Hardy-Weinberg equilibrium test statistics. Genetics.
180:1609–1616. 2008.PubMed/NCBI View Article : Google Scholar
|
25
|
Hou G, Jin Y, Liu M, Wang C and Song G:
UCP2-866G/A polymorphism is associated with prediabetes and type 2
diabetes. Arch Med Res. 51:556–563. 2020.PubMed/NCBI View Article : Google Scholar
|
26
|
Sohn KJ, Croxford R, Yates Z, Lucock M and
Kim YI: Effect of the methylenetetrahydrofolate reductase C677T
polymorphism on chemosensitivity of colon and breast cancer cells
to 5-fluorouracil and methotrexate. J Natl Cancer Inst. 96:134–144.
2004.PubMed/NCBI View Article : Google Scholar
|
27
|
Tang W, Zhang S, Qiu H, Wang L, Sun B, Yin
J and Gu H: Genetic variations in MTHFR and esophageal squamous
cell carcinoma susceptibility in Chinese Han population. Med Oncol.
31(915)2014.PubMed/NCBI View Article : Google Scholar
|
28
|
Lin J, Zeng RM, Li RN and Cao WH: Aberrant
DNA methylation of the P16, MGMT, and hMLH1 genes in combination
with the methylenetetrahydrofolate reductase C677T genetic
polymorphism and folate intake in gastric cancer. Genet Mol Res.
13:2060–2068. 2014.PubMed/NCBI View Article : Google Scholar
|
29
|
Chen J, Yuan L, Duan YQ, Jiang JQ, Zhang
R, Huang ZJ and Xiao XR: Impact of methylenetetrahydrofolate
reductase polymorphisms and folate intake on the risk of gastric
cancer and their association with Helicobacter pylori infection and
tumor site. Genet Mol Res. 13:9718–9726. 2014.PubMed/NCBI View Article : Google Scholar
|
30
|
Li S, Ji M, He N and Lu Z: Application of
microarray-based method for methylenetetrahydrofolate reductase
(MTHFR) polymorphisms in the risk of gastric carcinoma in east
China population. J Nanosci Nanotechnol. 7:3245–3249.
2007.PubMed/NCBI View Article : Google Scholar
|
31
|
Galván-Portillo MV, Oñate-Ocaña LF,
Pérez-Pérez GI, Chen J, Herrera-Goepfert R, Chihu-Amparan L,
Flores-Luna L, Mohar-Betancourt A and López-Carrillo L: Dietary
folate and vitamin B12 intake before diagnosis decreases gastric
cancer mortality risk among susceptible MTHFR 677TT carriers.
Nutrition. 26:201–208. 2010.PubMed/NCBI View Article : Google Scholar
|
32
|
Lu JW, Gao CM, Wu JZ, Sun XF, Wang L and
Feng JF: Relationship of methylenetetrahydrofolate reductase C677T
polymorphism and chemosensitivity to 5-fluorouracil in gastric
carcinoma. Ai Zheng. 23:958–962. 2004.PubMed/NCBI(In Chinese).
|
33
|
Rozen R: Molecular genetics of
methylenetetrahydrofolate reductase deficiency. J Inherit Metab
Dis. 19:589–594. 1996.PubMed/NCBI View Article : Google Scholar
|
34
|
Custodio A, Moreno-Rubio J, Aparicio J,
Gallego-Plazas J, Yaya R, Maurel J, Rodríguez-Salas N, Burgos E,
Ramos D, Calatrava A, et al: Pharmacogenetic predictors of outcome
in patients with stage II and III colon cancer treated with
oxaliplatin and fluoropyrimidine-based adjuvant chemotherapy. Mol
Cancer Ther. 13:2226–2237. 2014.PubMed/NCBI View Article : Google Scholar
|
35
|
Cecchin E, Perrone G, Nobili S, Polesel J,
De Mattia E, Zanusso C, Petreni P, Lonardi S, Pella N, D'Andrea M,
et al: MTHFR-1298 A>C (rs1801131) is a predictor of survival in
two cohorts of stage II/III colorectal cancer patients treated with
adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin.
Pharmacogenomics J. 15:219–225. 2015.PubMed/NCBI View Article : Google Scholar
|
36
|
De Mattia E and Toffoli G: C677T and
A1298C MTHFR polymorphisms, a challenge for antifolate and
fluoropyrimidine-based therapy personalisation. Eur J Cancer.
45:1333–1351. 2009.PubMed/NCBI View Article : Google Scholar
|
37
|
Ramos-Esquivel A, Chinchilla R and Valle
M: Association of C677T and A1298C MTHFR polymorphisms and
fluoropyrimidine-induced toxicity in mestizo patients with
metastatic colorectal cancer. Anticancer Res. 40:4263–4270.
2020.PubMed/NCBI View Article : Google Scholar
|
38
|
Chen L, Lu N, Zhang BH, Weng LI and Lu J:
Association between the MTHFR C677T polymorphism and gastric cancer
susceptibility: A meta-analysis of 5,757 cases and 8,501 controls.
Oncol Lett. 10:1159–1165. 2015.PubMed/NCBI View Article : Google Scholar
|
39
|
Zintzaras E: Association of
methylenetetrahydrofolate reductase (MTHFR) polymorphisms with
genetic susceptibility to gastric cancer: A meta-analysis. J Hum
Genet. 51:618–624. 2006.PubMed/NCBI View Article : Google Scholar
|
40
|
Liew SC and Gupta ED:
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism:
Epidemiology, metabolism and the associated diseases. Eur J Med
Genet. 58:1–10. 2015.PubMed/NCBI View Article : Google Scholar
|
41
|
Beckett EL, Martin C, Choi JH, King K,
Niblett S, Boyd L, Duesing K, Yates Z, Veysey M and Lucock M:
Folate status, folate-related genes and serum miR-21 expression:
Implications for miR-21 as a biomarker. BBA Clin. 4:45–51.
2015.PubMed/NCBI View Article : Google Scholar
|
42
|
He WA, Calore F, Londhe P, Canella A,
Guttridge DC and Croce CM: Microvesicles containing miRNAs promote
muscle cell death in cancer cachexia via TLR7. Proc Natl Acad Sci
USA. 111:4525–4529. 2014.PubMed/NCBI View Article : Google Scholar
|
43
|
Vidmar Golja M, Smid A, Karas Kuzelicki N,
Trontelj J, Gersak K and Mlinaric-Rascan I: Folate insufficiency
due to MTHFR deficiency is bypassed by 5-methyltetrahydrofolate. J
Clin Med. 9:2020.PubMed/NCBI View Article : Google Scholar
|
44
|
Kim YI: Methylenetetrahydrofolate
reductase polymorphisms, folate, and cancer risk: A paradigm of
gene-nutrient interactions in carcinogenesis. Nutr Rev. 58:205–209.
2000.PubMed/NCBI View Article : Google Scholar
|
45
|
Tan W, Miao X, Wang L, Yu C, Xiong P,
Liang G, Sun T, Zhou Y, Zhang X, Li H and Lin D: Significant
increase in risk of gastroesophageal cancer is associated with
interaction between promoter polymorphisms in thymidylate synthase
and serum folate status. Carcinogenesis. 26:1430–1435.
2005.PubMed/NCBI View Article : Google Scholar
|
46
|
Chai W, Zhang Z, Ni M, Geng P, Lian Z,
Zhang G, Shi LL and Chen J: Genetic association between
methylenetetrahydrofolate reductase gene polymorphism and risk of
osteonecrosis of the femoral head. Biomed Res Int.
2015(196495)2015.PubMed/NCBI View Article : Google Scholar
|
47
|
Jain M, Pandey P, Tiwary NK and Jain S:
MTHFR C677T polymorphism is associated with hyperlipidemia in women
with polycystic ovary syndrome. J Hum Reprod Sci. 5:52–56.
2012.PubMed/NCBI View Article : Google Scholar
|
48
|
Födinger M, Wagner OF, Hörl WH and
Sunder-Plassmann G: Recent insights into the molecular genetics of
the homocysteine metabolism. Kidney Int Suppl. 78:S238–S242.
2001.PubMed/NCBI View Article : Google Scholar
|
49
|
Kim YI: Role of the MTHFR polymorphisms in
cancer risk modification and treatment. Future Oncol. 5:523–542.
2009.PubMed/NCBI View Article : Google Scholar
|
50
|
Bezerra JF, Oliveira GH, Soares CD,
Cardoso ML, Ururahy MA, Neto FP, Lima-Neto LG, Luchessi AD,
Silbiger VN, Fajardo CM, et al: Genetic and non-genetic factors
that increase the risk of non-syndromic cleft lip and/or palate
development. Oral Dis. 21:393–399. 2015.PubMed/NCBI View Article : Google Scholar
|
51
|
Ericson UC, Ivarsson MI, Sonestedt E,
Gullberg B, Carlson J, Olsson H and Wirfält E: Increased breast
cancer risk at high plasma folate concentrations among women with
the MTHFR 677T allele. Am J Clin Nutr. 90:1380–1389.
2009.PubMed/NCBI View Article : Google Scholar
|