Open Access

Clinical characteristics among patients with COVID‑19: A single‑center retrospective study

  • Authors:
    • Anjum Farhana
    • Bilal Ahmad Tantry
    • Naveed Nazir Shah
    • Altaf Bandy
    • Mudasar Nabi
    • Syed Quibtiya Khursheed
    • Mir Shahnawaz
    • Hena Mustafa
  • View Affiliations

  • Published online on: October 14, 2022     https://doi.org/10.3892/br.2022.1577
  • Article Number: 94
  • Copyright: © Farhana et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the present study was to investigate the clinical features and laboratory parameters of hospitalized patients with coronavirus disease 2019 (COVID‑19) and assess the characteristics between severe and non‑severe cases. The study retrospectively analyzed the clinical data of 1,096 patients, of which, 626 (57.11%) and 470 (42.89%) were categorized into severe and non‑severe groups, respectively. Clinical parameters such as signs and symptoms, comorbidities, levels of D‑dimer, C‑reactive protein (CRP), interleukin 6 (IL‑6) and lactate dehydrogenase were analyzed. The data are presented as frequencies, means and standard deviations. The chi‑square test and Mann‑Whitney U test were used to assess any significant differences between the severe and non‑severe COVID‑19 groups. The clinical symptoms in severe COVID‑19 cases included anosmia (P≤0.01), sore throat (P≤0.01), fatigue (P≤0.01), headache (P≤0.01), and shortness of breath (P≤0.01). Laboratory findings showed a significant increase in CRP (21.90±40.23 vs. 16.13±21.82; P≤0.01) and IL‑6 levels (58.92±55.07 vs. 41.41±38.30; P≤0.01). Patients with severe COVID‑19 had significant lymphopenia compared with that in non‑severe cases. Among the comorbidities, hypertension (P≤0.01) was significantly more frequent in patients with severe COVID‑19. In conclusion, major derangements in laboratory parameters were observed in patients with severe COVID‑19 infection.
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Spandidos Publications style
Farhana A, Tantry BA, Shah NN, Bandy A, Nabi M, Khursheed SQ, Shahnawaz M and Mustafa H: Clinical characteristics among patients with COVID‑19: A single‑center retrospective study. Biomed Rep 17: 94, 2022.
APA
Farhana, A., Tantry, B.A., Shah, N.N., Bandy, A., Nabi, M., Khursheed, S.Q. ... Mustafa, H. (2022). Clinical characteristics among patients with COVID‑19: A single‑center retrospective study. Biomedical Reports, 17, 94. https://doi.org/10.3892/br.2022.1577
MLA
Farhana, A., Tantry, B. A., Shah, N. N., Bandy, A., Nabi, M., Khursheed, S. Q., Shahnawaz, M., Mustafa, H."Clinical characteristics among patients with COVID‑19: A single‑center retrospective study". Biomedical Reports 17.6 (2022): 94.
Chicago
Farhana, A., Tantry, B. A., Shah, N. N., Bandy, A., Nabi, M., Khursheed, S. Q., Shahnawaz, M., Mustafa, H."Clinical characteristics among patients with COVID‑19: A single‑center retrospective study". Biomedical Reports 17, no. 6 (2022): 94. https://doi.org/10.3892/br.2022.1577