Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
September-2023 Volume 19 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September-2023 Volume 19 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma

  • Authors:
    • Makoto Takahashi
    • Yasuhiro Morita
    • Tatsuya Hayashi
    • Taku Higashihara
    • Keishi Kawasaki
    • Shunsuke Sato
    • Shota Yokose
    • Shu Sasaki
    • Kaoruko Funakoshi
    • Takayoshi Sasaki
    • Daren Zhou
    • Akinori Ichinose
    • Hideo Ohtsuka
    • Yuji Ishibashi
    • Fumihiko Hatao
    • Keiki Shimizu
    • Nobuo Isono
    • Naomi Sasaki
    • Yasuji Kozai
    • Haruka Okada
    • Yushi Chikasawa
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Tokyo Metropolitan Tama Medical Center, Tokyo 183‑8524, Japan, Department of Critical Care and Emergency Medicine, Tokyo Metropolitan Tama Medical Center, Tokyo 183‑8524, Japan, Department of Plastic Surgery, Tokyo Metropolitan Tama Medical Center, Tokyo 183‑8524, Japan, Department of Nursing, Tokyo Metropolitan Tama Medical Center, Tokyo 183‑8524, Japan, Department of Hematology, Tokyo Metropolitan Tama Medical Center, Tokyo 183‑8524, Japan, Department of Pathology, Tokyo Metropolitan Tama Medical Center, Tokyo 183‑8524, Japan, Department of Laboratory Medicine, Tokyo Medical University, Tokyo 183‑8524, Japan
    Copyright: © Takahashi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 61
    |
    Published online on: August 1, 2023
       https://doi.org/10.3892/br.2023.1643
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:


Abstract

Acquired hemophilia A (AHA) is a rare disease that results from factor VIII inhibitors causing abnormal coagulation, and certain cases may develop after highly invasive surgery. The present case study reports on a 68‑year‑old male patient who developed AHA after undergoing a subtotal stomach‑preserving pancreatoduodenectomy for distal cholangiocarcinoma. The patient experienced complications after surgery, requiring reoperation on postoperative day (PD) 5 due to rupture of the Braun's enterostomy. On PD 6, angiography was performed after bleeding was detected in the jejunal limb, but hemostasis occurred spontaneously during the examination. Bleeding was observed again on PD 8 and direct surgical ligation was performed. On PD 14, bleeding recurred in the jejunal limb and angiography was performed to embolize the periphery of the second jejunal artery. During the procedure, the prothrombin time was normal, but only the activated partial thromboplastin time was prolonged. A close examination of the coagulation system revealed a decrease in factor VIII levels and the presence of factor VIII inhibitors, resulting in the diagnosis of AHA. Administration of steroids was initiated on PD 15 and, in addition to daily blood transfusions, activated prothrombin complex concentrate was administered to achieve hemostasis. The patient was discharged from the intensive care unit on PD 36 but later developed an intractable labial fistula due to suture failure at the gastrojejunostomy site. As the use of factor VIII inhibitors continued despite the administration of steroids, cyclophosphamide (CPA) pulse therapy was added at PD 58. However, CPA was ineffective and the administration of rituximab was initiated on PD 98. After 12 courses of rituximab, the patient tested negative for factor VIII inhibitors on PD 219. On PD 289, labial fistula closure was performed with continuous replacement of factor VIII and the patient was discharged on PD 342.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

View References

1 

Huth-Kühne A, Baudo F, Collins P, Ingerslev J, Kessler CM, Lévesque H, Castellano ME, Shima M and St-Louis J: International recommendations on the diagnosis and treatment of patients with acquired hemophilia A. Haematologica. 94:566–575. 2009.PubMed/NCBI View Article : Google Scholar

2 

Ogawa Y, Yanagisawa K, Uchiumi H, Ishizaki T, Mitsui T, Gouda F, Ieko M, Ichinose A, Nojima Y and Handa H: Clinical characteristics and outcomes of acquired hemophilia A: experience at a single center in Japan. Int J Hematol. 106:82–89. 2017.PubMed/NCBI View Article : Google Scholar

3 

Ogawa Y, Amano K, Matsuo-Tezuka Y, Okada N, Murakami Y, Nakamura T, Yamaguchi-Suita H and Nogami K: ORIHIME study: Real-world treatment patterns and clinical outcomes of 338 patients with acquired hemophilia A from a Japanese administrative database. Int J Hematol. 117:44–55. 2023.PubMed/NCBI View Article : Google Scholar

4 

Tiede A, Werwitzke S and Scharf RE: Laboratory diagnosis of acquired hemophilia A: Limitations, consequences, and challenges. Semin Thromb Hemost. 40:803–811. 2014.PubMed/NCBI View Article : Google Scholar

5 

Tiede A, Collins P, Knoebl P, Teitel J, Kessler C, Shima M, Di Minno G, d'Oiron R, Salaj P, Jiménez-Yuste V, et al: International recommendations on the diagnosis and treatment of acquired hemophilia A. Haematologica. 105:1791–1801. 2020.PubMed/NCBI View Article : Google Scholar

6 

Delgado J, Jimenez-Yuste V, Hernandez-Navarro F and Villar A: Acquired haemophilia: Review and meta-analysis focused on therapy and prognostic factors. Br J Haematol. 121:21–35. 2003.PubMed/NCBI View Article : Google Scholar

7 

Collins PW, Hirsch S, Baglin TP, Dolan G, Hanley J, Makris M, Keeling DM, Liesner R, Brown SA and Hay CR: UK Haemophilia Centre Doctors' Organisation. Acquired hemophilia A in the United Kingdom: A 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation. Blood. 109:1870–1877. 2007.PubMed/NCBI View Article : Google Scholar

8 

Bossi P, Cabane J, Ninet J, Dhote R, Hanslik T, Chosidow O, Jouan-Flahault C, Horellou MH, Leynadier F, Liozon E, et al: Acquired hemophilia due to factor VIII inhibitors in 34 patients. Am J Med. 105:400–408. 1998.PubMed/NCBI View Article : Google Scholar

9 

Morrison AE, Ludlam CA and Kessler C: Use of porcine factor VIII in the treatment of patients with acquired hemophilia. Blood. 81:1513–1520. 1993.PubMed/NCBI

10 

Green D and Lechner K: A survey of 215 non-hemophilic patients with inhibitors to Factor VIII. Thromb Haemost. 45:200–203. 1981.PubMed/NCBI

11 

Miura T, Ban D, Koyama T, Kudo A, Ochiai T, Irie T, Nakamura N, Tanaka S and Arii S: Severe postoperative hemorrhage caused by antibody-mediated coagulation factor deficiencies: Report of two cases. Surg Today. 44:976–981. 2014.PubMed/NCBI View Article : Google Scholar

12 

Mekenkamp LJ, Beishuizen A, Slomp J, Legdeur MC, Klaase JM and Trof RJ: Successful treatment of fulminant postoperative bleeding due to acquired haemophilia. Neth J Med. 73:182–186. 2015.PubMed/NCBI

13 

Suzuki N, Hirakawa A, Kishimoto M, Kanematsu T, Ogawa M, Kiyoi H and Matsushita T: Retrospective analysis of in vivo recovery and clearance during continuous infusion of recombinant factor VIII products: A single-institution study. Haemophilia. 23:215–221. 2017.PubMed/NCBI View Article : Google Scholar

14 

Napolitano M, Siragusa S, Mancuso S and Kessler CM: Acquired haemophilia in cancer: A systematic and critical literature review. Haemophilia. 24:43–56. 2018.PubMed/NCBI View Article : Google Scholar

15 

Geethakumari PR, Sama A, Caro JG, Yeo CJ and Nagalla S: ‘The Immune Conundrum’: Acquired Hemophilia A, immune thrombocytopenia, and neutropenia in a patient with pancreatic cancer. Case Rep Pancreat Cancer. 2:14–18. 2016.PubMed/NCBI View Article : Google Scholar

16 

Sallah S: Treatment of acquired haemophilia with factor eight inhibitor bypassing activity. Haemophilia. 10:169–173. 2004.PubMed/NCBI View Article : Google Scholar

17 

Tiede A and Worster A: Lessons from a systematic literature review of the effectiveness of recombinant factor VIIa in acquired haemophilia. Ann Hematol. 97:1889–1901. 2018.PubMed/NCBI View Article : Google Scholar

18 

Kruse-Jarres R, St-Louis J, Greist A, Shapiro A, Smith H, Chowdary P, Drebes A, Gomperts E, Bourgeois C, Mo M, et al: Efficacy and safety of OBI-1, an antihaemophilic factor VIII (recombinant), porcine sequence, in subjects with acquired haemophilia A. Haemophilia. 21:162–170. 2015.PubMed/NCBI View Article : Google Scholar

19 

Tiede A, Klamroth R, Scharf RE, Trappe RU, Holstein K, Huth-Kühne A, Gottstein S, Geisen U, Schenk J, Scholz U, et al: Prognostic factors for remission of and survival in acquired hemophilia A (AHA): Results from the GTH-AH 01/2010 study. Blood. 125:1091–1097. 2015.PubMed/NCBI View Article : Google Scholar

20 

Collins P, Baudo F, Knoebl P, Lévesque H, Nemes L, Pellegrini F, Marco P, Tengborn L and Huth-Kühne A: Immunosuppression for acquired hemophilia A: Results from the European Acquired Haemophilia Registry (EACH2). Blood. 120:47–55. 2012.PubMed/NCBI View Article : Google Scholar

21 

Franchini M: Acquired hemophilia A. Hematology. 11:119–125. 2006.PubMed/NCBI View Article : Google Scholar

22 

Gok E, Akay MH, de Armas IS, Klein K, Tint H, Allison PM, Chen AJ, Akkanti B, Kar B and Gregoric ID: Aortic root repair in a patient with acquired hemophilia A: case report. Surg Case Rep. 7(176)2021.PubMed/NCBI View Article : Google Scholar

23 

Tjønnfjord GE, Brinch L, Gedde-Dahl T and Brosstad FR: Activated prothrombin complex concentrate (FEIBA) treatment during surgery in patients with inhibitors to FVIII/IX. Haemophilia. 10:174–178. 2004.PubMed/NCBI View Article : Google Scholar

24 

Hay CR, Negrier C and Ludlam CA: The treatment of bleeding in acquired haemophilia with recombinant factor VIIa: A multicentre study. Thromb Haemost. 78:1463–1467. 1997.PubMed/NCBI

25 

Ichikawa S, Kohata K, Okitsu Y, Suzuki M, Nakajima S, Yamada MF, Onishi Y, Yamamoto J, Suzuki S, Ishizawa K, et al: Acquired hemophilia A with sigmoid colon cancer: Successful treatment with rituximab followed by sigmoidectomy. Int J Hematol. 90:33–36. 2009.PubMed/NCBI View Article : Google Scholar

26 

Jena SS, Meher D and Dhankar N: Unforeseen encounter of acquired hemophilia A in a preoperative case of periampullary carcinoma: A case report. Int J Surg Case Rep. 79:146–149. 2021.PubMed/NCBI View Article : Google Scholar

27 

Kruse-Jarres R, Kempton CL, Baudo F, Collins PW, Knoebl P, Leissinger CA, Tiede A and Kessler CM: Acquired hemophilia A: Updated review of evidence and treatment guidance. Am J Hematol. 92:695–705. 2017.PubMed/NCBI View Article : Google Scholar

28 

Shen M, Wang S, Sessa J, Hanna A, Axelrad A and Ali F: Acquired hemophilia A: A case report. J Pharm Pract. 33:562–566. 2020.PubMed/NCBI View Article : Google Scholar

29 

Prencipe MA, D'Errico M, Di Giorgio G, Gatta G, Gesuete A, Nobile M and Stallone C: Macrohaematuria post-partum: An unusual case of acquired haemophilia after pregnancy. G Ital Nefrol. 19:204–208. 2002.PubMed/NCBI(In Italian).

30 

Baudo F, Collins P, Huth-Kühne A, Lévesque H, Marco P, Nemes L, Pellegrini F, Tengborn L and Knoebl P: EACH2 registry contributors. Management of bleeding in acquired hemophilia A: results from the European Acquired Haemophilia (EACH2) Registry. Blood. 120:39–46. 2012.PubMed/NCBI View Article : Google Scholar

31 

Lindahl R, Nummi V, Lehtinen AE, Szanto T, Hiltunen L, Olsson A, Glenthoej A, Chaireti R, Vaide I, Funding E and Zetterberg E: Acquired Haemophilia A in four north European countries: Survey of 181 patients. Br J Haematol. 201:326–333. 2023.PubMed/NCBI View Article : Google Scholar

32 

Guerra JD, Gowarty J, Buess J, Mason J and Halka K: A case of acquired hemophilia a in a patient with exposure to COVID-19. Case Rep Hematol. 2022(9494249)2022.PubMed/NCBI View Article : Google Scholar

33 

Murali A, Wong P, Gilbar PJ and Mangos HM: Acquired Hemophilia A following Pfizer-BioNTech SARS CoV-2 mRNA vaccine, successfully treated with prednisolone and rituximab. J Oncol Pharm Pract. 28:1450–1453. 2022.PubMed/NCBI View Article : Google Scholar

34 

Franchini M, Cappello E, Valdiserra G, Bonaso M, Moretti U, Focosi D and Tuccori M: Investigating a signal of acquired hemophilia associated with COVID-19 Vaccination: A systematic case review. Semin Thromb Hemost. 49:15–26. 2023.PubMed/NCBI View Article : Google Scholar

35 

Shoji-Asahina A, Nakatani E, Imaichi Y, Ohata E, Oshima M, Miyakoshi A, Miyake H, Ichikawa Y, Dote H, Ubukata N, et al: Risk factors, treatment and survival rates of late-onset acquired haemophilia A: A cohort study from the Shizuoka Kokuho Database. Haemophilia. 29:799–808. 2023.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Takahashi M, Morita Y, Hayashi T, Higashihara T, Kawasaki K, Sato S, Yokose S, Sasaki S, Funakoshi K, Sasaki T, Sasaki T, et al: A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma. Biomed Rep 19: 61, 2023.
APA
Takahashi, M., Morita, Y., Hayashi, T., Higashihara, T., Kawasaki, K., Sato, S. ... Chikasawa, Y. (2023). A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma. Biomedical Reports, 19, 61. https://doi.org/10.3892/br.2023.1643
MLA
Takahashi, M., Morita, Y., Hayashi, T., Higashihara, T., Kawasaki, K., Sato, S., Yokose, S., Sasaki, S., Funakoshi, K., Sasaki, T., Zhou, D., Ichinose, A., Ohtsuka, H., Ishibashi, Y., Hatao, F., Shimizu, K., Isono, N., Sasaki, N., Kozai, Y., Okada, H., Chikasawa, Y."A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma". Biomedical Reports 19.3 (2023): 61.
Chicago
Takahashi, M., Morita, Y., Hayashi, T., Higashihara, T., Kawasaki, K., Sato, S., Yokose, S., Sasaki, S., Funakoshi, K., Sasaki, T., Zhou, D., Ichinose, A., Ohtsuka, H., Ishibashi, Y., Hatao, F., Shimizu, K., Isono, N., Sasaki, N., Kozai, Y., Okada, H., Chikasawa, Y."A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma". Biomedical Reports 19, no. 3 (2023): 61. https://doi.org/10.3892/br.2023.1643
Copy and paste a formatted citation
x
Spandidos Publications style
Takahashi M, Morita Y, Hayashi T, Higashihara T, Kawasaki K, Sato S, Yokose S, Sasaki S, Funakoshi K, Sasaki T, Sasaki T, et al: A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma. Biomed Rep 19: 61, 2023.
APA
Takahashi, M., Morita, Y., Hayashi, T., Higashihara, T., Kawasaki, K., Sato, S. ... Chikasawa, Y. (2023). A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma. Biomedical Reports, 19, 61. https://doi.org/10.3892/br.2023.1643
MLA
Takahashi, M., Morita, Y., Hayashi, T., Higashihara, T., Kawasaki, K., Sato, S., Yokose, S., Sasaki, S., Funakoshi, K., Sasaki, T., Zhou, D., Ichinose, A., Ohtsuka, H., Ishibashi, Y., Hatao, F., Shimizu, K., Isono, N., Sasaki, N., Kozai, Y., Okada, H., Chikasawa, Y."A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma". Biomedical Reports 19.3 (2023): 61.
Chicago
Takahashi, M., Morita, Y., Hayashi, T., Higashihara, T., Kawasaki, K., Sato, S., Yokose, S., Sasaki, S., Funakoshi, K., Sasaki, T., Zhou, D., Ichinose, A., Ohtsuka, H., Ishibashi, Y., Hatao, F., Shimizu, K., Isono, N., Sasaki, N., Kozai, Y., Okada, H., Chikasawa, Y."A case of acquired hemophilia A after pancreaticoduodenectomy for distal cholangiocarcinoma". Biomedical Reports 19, no. 3 (2023): 61. https://doi.org/10.3892/br.2023.1643
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team