Long-term efficacy of intermittent peritoneal dialysis using various doses

Zhang,Zhi-Yong; Zhou,Chun-Hua; Li,Ming-Xu; Yu,Yong-Wu

doi:10.3892/etm.2011.444

Long-term efficacy of intermittent peritoneal dialysis using various doses

Authors:
- Zhi-Yong Zhang
- Chun-Hua Zhou
- Ming-Xu Li
- Yong-Wu Yu
View Affiliations

Affiliations: Department of Nephrology, Naval General Hospital of PLA, Beijing 100048, P.R. China
Published online on: December 30, 2011 https://doi.org/10.3892/etm.2011.444
Pages: 519-524

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

The objective of the present study was to investigate the long-term clinical efficacy of intermittent peritoneal dialysis (IPD) using various doses and to explore the most suitable dialysis dose and practice pattern for patients. A total of 52 inpatients/outpatients who had undergone IPD for more than 5 years were recruited and divided into three groups according to the dialysis dose: 4 liters in Group A, 6 liters in Group B and 8 liters in Group C. The dwell time was 4 h. All patients were fasted overnight. The dialysis adequacy, nutritional status, complication control, blood pressure and intra-abdominal infection were determined and observed among these patients. Barthel index (BI) and Hamilton Depression Scale (HAMD) were employed to measure the activities of daily living (ADL) and degree of depression, respectively. The dialysis adequacy and ultrafiltration volume in Group A were lower than those in Groups B and C, but the residual urine volume was larger than that in the latter two groups. In addition, there was a marked difference in the control of complications between Group A and Groups B and C. When compared to Groups A and B, the nutritional status in Group C was significantly decreased, the mean arterial pressure and intra-abdominal infection rates were dramatically increased, and the HAMD scores were also higher (P<0.05). No significant difference was noted in the BI. For patients undergoing long-term IPD, individualized dialysis dose may benefit the dialysis adequacy, nutritional status, control of complications, blood pressure, rate of intra-abdominal infection, ADL and depression.

View Figures

View References

1.	JM BurkartThe ADEMEX study and PD adequacyBlood Purif213741200310.1159/00006787012566659
2.	CQ PuSY LangWP WuRehabilitation of cerebrovascular diseaseCerebrovascular DiseasePeople's Military Medical PressBeijing5205381999
3.	ZJ CaiDepression in Basic and Clinical MedicineScience PressBeijing861091997
4.	GA ColesClinical research in peritoneal dialysisContrib Nephrol13112521312001
5.	R GokalPeritoneal dialysis in the 21st century: an analysis of current problems and future developmentsJ Am Soc Nephrol1310421162002
6.	AE GrzegorzewskaWhat is new in peritoneal dialysis in the years 2003–2004 (J)Rocz Akad Med Bialymst4917021732004
7.	T WangRG YePeritoneal dialysis should be the preferred choice in the treatment of end-stage renal failure in ChinaChin J Integ Tradit West Nephrol312002
8.	MA BajoML Pérez-LozanoP Albar-VizcainoLow-GDP peritoneal dialysis fluid (‘balance’) has less impact in vitro and ex vivo on epithelial-to-mesenchymal transition (EMT) of mesothelial cells than a standard fluidNephrol Dial Transplant262822912011
9.	M FahimCM HawleySP McDonaldCoagulase-negative staphylococcal peritonitis in Australian peritoneal dialysis patients: predictors, treatment and outcomes in 936 casesNephrol Dial Transplant2533863392201010.1093/ndt/gfq222
10.	T ShimadaI UrakawaT IsakovaCirculating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically activeClin Endocrinol Metab95578585201010.1210/jc.2009-1603
11.	FH BenderJ BernardiniB PirainoPrevention of infectious complications in peritoneal dialysis: best demonstrated practicesKidney Int Suppl103S44S54200610.1038/sj.ki.500191517080111
12.	TO BenderM BöhmK KratochwillPeritoneal dialysis fluids can alter HSP expression in human peritoneal mesothelial cellsNephrol Dial Transplant2610461052201110.1093/ndt/gfq48420713976
13.	T LindenB MusiK JarkelidGlucose degradation products in peritoneal dialysis fluids may have both local and systemic effects: a study of residual fluid and mesothelial cellsPerit Dial Int2160726102001
14.	J DongThe investigation of adequacy parameters and their ideal values for peritoneal dialysisChin J Blood Purif95265282010
15.	BP TeehanCR SchleiferMH SiglerA quantitative approach to the CAPD prescriptionPerit Dial Bull51521985
16.	R PaniaguaD AmatoE VoneshEffects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMEX, a prospective, randomized, controlled trialJ Am Soc Nephrol13130713202002
17.	R BrunkhorstHypervolemia, arterial hypertension and cardiovascular disease: a largely neglected problem in peritoneal dialysisClin Nephrol69233238200810.5414/CNP6923318397696
18.	BG StegmayrUltrafiltration and dry weight - What are the cardiovascular effectsArtif Organs27227229200310.1046/j.1525-1594.2003.07205.x12662207
19.	ZH GuiHL WangJY ZhangMalnutrition inflammation score can evaluate malnutrition-inflammation status in Chinese peritoneal dialysis patientsChin J Blood Purif95295332010
20.	NV DombrosPathogenesis and management of malnutrition in chronic peritoneal dialysis patientsNephrol Dial Transplant16Suppl 6111113200110.1093/ndt/16.suppl_6.11111568265
21.	CANADA - USA (CANUSA) Peritoneal Dialysis Study GroupAdequacy of dialysis and nutrition in continuous peritoneal dialysis: association with clinical outcomesJ Am Soc Nephrol719820719968785388
22.	N ZhuWJ YuanJ LiuCorrelation of high mobility group box protein 1 with microinflammatory state and nutritional status in continuous ambulatory peritoneal dialysis patientsChin J Nephrol268018022010
23.	KN LaiWK LoOptimal peritoneal dialysis for patients from Hong KongPerit Dial Int19Suppl 326311999
24.	WC LyePS ChanSO LeongPsychosocial and psychiatric morbidity in patients on CAPDAdv Perit Dial1313413619979360667
25.	PH JuergensenA ZemchenkovS WatnickComparison of quality-of-life assessment in Russia and the United States in chronic peritoneal dialysis patientsAdv Perit Dial185557200212402587
26.	GA HinrichsenJA LiebermanS PollackDepression in hemodialysis patientsPsychosomatics30284289198910.1016/S0033-3182(89)72273-8
27.	NG KutnerR ZhangWM McClellanPatient-reported quality of life early in dialysis treatment: the effects associated with usual exercise activityNephrol Nurs J27357367200011276627
28.	AM O'HareK TawneyP BacchettiKL JohansenDecreased survival among sedentary patients undergoing dialysis: results from the dialysis morbidity and mortality study waveAm J Kidney Dis41447454200312552509