Association between subclinical hypothyroidism and Sasang constitution in a Korean population
- Authors:
- Se-Young Ahn
- Sung-Hwan Park
- Su-Ryun Han
- Young-Min Ahn
- Byung-Cheol Lee
View Affiliations
Affiliations: Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University, Seoul 130-702, Republic of Korea
- Published online on: January 30, 2012 https://doi.org/10.3892/etm.2012.461
-
Pages:
740-744
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Abstract
Serum thyroid-stimulating hormone screening of asymptomatic individuals to diagnose subclinical hypothyroidism remains controversial. We evaluated the potential role of Sasang constitutional discrimination and ryodoraku testing as an alternative and complementary diagnostic tool for subclinical hypothyroidism. Among 1,105 potential subjects, 1,073 were included in this study. Of these, 134 subjects had subclinical hypothyroidism (SCH) and 939 were healthy (euthyroid; EU) control subjects. Blood parameters, including serum thyroid hormone levels, were measured. We classified the participants into the four Sasang constitutional types, Taeyang-type individuals, Taeeum-type individuals, Soyang-type individuals and Soeum-type individuals, and measured their ryodoraku scores (RS). The mean levels of free thyroxine (FT4), glucose, red blood cells and hematocrit in the SCH group were significantly lower compared to those in the EU group (p<0.0183, p=0.0006, p=0.0162 and p=0.0224, respectively). The mean FT4 level of the Soeum-type SCH patients was significantly lower compared to the Soeum-type EU patients (p=0.0423). The total RS was significantly higher in the Taeeum-type SCH patients (p=0.0253) and lower in the Soeum-type SCH patients (p=0.0094) compared to controls. Ryodoraku testing and Sasang constitutional discrimination have the potential to serve as alternative and complementary diagnostic tools for subclinical hypothyroidism.
View References
1.
|
Haentjens P, Van Meerhaeghe A, Poppe K and
Velkeniers B: Subclinical thyroid dysfunction and mortality: an
estimate of relative and absolute excess all-cause mortality based
on time-to-event data from cohort studies. Eur J Endocrinol.
159:329–341. 2008. View Article : Google Scholar : PubMed/NCBI
|
2.
|
Mizokami T, Wu LA, El Kaissi S and Wall
JR: Stress and thyroid autoimmunity. Thyroid. 14:1047–1055. 2004.
View Article : Google Scholar
|
3.
|
Lee CT, Chang YH, Lin WY, et al:
Applications of meridian electrical conductance for renal colic: a
prospective study. J Altern Complement Med. 16:861–866. 2010.
View Article : Google Scholar : PubMed/NCBI
|
4.
|
Lee BC, Lee H, Park HK, Yang JS and Chung
JH: Susceptibility for ischemic stroke in four constitution
medicine is associated with polymorphisms of FCGR2A and IL1RN
genes. Neurol Res. 32:43–47. 2010. View Article : Google Scholar : PubMed/NCBI
|
5.
|
Choi EY and Chang BS: A study on the
differences of stress responses according to sasang constitutions.
Kor J Oriental Preventive Medicine. 123:175–183. 2008.
|
6.
|
Ismail AA: On the diagnosis of subclinical
hypothyroidism. Br J Gen Pract. 57:1000–1001. 2007. View Article : Google Scholar : PubMed/NCBI
|
7.
|
Koh BH, Kim SH, Park BG, et al: A study on
the Sasang constitutional distribution among the people in the
United States of America. J Sasang Const Med. 11:119–150. 1999.
|
8.
|
Chae H, Park SH, Lee SJ, Kim MG, Wedding D
and Kwon YK: Psychological profile of sasang typology: a systematic
review. Evid Based Complement Alternat Med. 61:21–29. 2009.
View Article : Google Scholar
|
9.
|
Lee GR, Shin DY, Kim YW, Yi JH, Song JM
and Kim LH: Changes of HRV according to emotional stimulus in
sasang constitutional groups. J Oriental Neuropsychiatry. 18:25–34.
2009.
|
10.
|
Jeon EY and Kim KB: A research on health
state according to stress perceptual level by constitution of the
Korean. J Korean Acad Nurs. 22:17–28. 1992.
|