Fish intake and risk of heart failure: A meta‑analysis of five prospective cohort studies

  • Authors:
    • Li-Na Hou
    • Fei Li
    • You Zhou
    • Shi-Huai Nie
    • Liang Su
    • Ping‑An Chen
    • Wan-Long Tan
    • Ding-Li Xu
  • View Affiliations

  • Published online on: June 8, 2012     https://doi.org/10.3892/etm.2012.605
  • Pages: 481-486
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Abstract

The findings on the association between fish intake and the risk of heart failure (HF) have been inconsistent. The purpose of this study was to clarify this potential association. We searched for relevant studies in the PubMed database through January 2012 and manually reviewed references. Five independent prospective cohort studies involving 5,273 cases and 144,917 participants were included. The summary relative risk estimates (SRRE) based on the highest compared with the lowest category of fish consumption were estimated by variance-based meta-analysis. In addition, we performed sensitivity and dose-response analyses to examine the association. Overall, an absence of an association between fish intake and HF was observed (SRRE=1.00; 95% CI, 0.81-1.24). However, fried fish intake positively associated with HF (SRRE=1.40; 95% CI, 1.22-1.61). In addition, dose-response analysis of fried fish suggested that each increment of six fried fish per month corresponded to a 37% increase of HF rate (RR=1.37; 95% CI, 1.20-1.56). In conclusion, our findings suggest that there is no significant association between fish intake and risk of HF, with the exception of a possible positive correlation with individuals comsuming fried fish, based on a limited number of studies. Future studies are required to confirm these findings.
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September 2012
Volume 4 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Hou L, Li F, Zhou Y, Nie S, Su L, Chen PA, Tan W and Xu D: Fish intake and risk of heart failure: A meta‑analysis of five prospective cohort studies. Exp Ther Med 4: 481-486, 2012.
APA
Hou, L., Li, F., Zhou, Y., Nie, S., Su, L., Chen, P. ... Xu, D. (2012). Fish intake and risk of heart failure: A meta‑analysis of five prospective cohort studies. Experimental and Therapeutic Medicine, 4, 481-486. https://doi.org/10.3892/etm.2012.605
MLA
Hou, L., Li, F., Zhou, Y., Nie, S., Su, L., Chen, P., Tan, W., Xu, D."Fish intake and risk of heart failure: A meta‑analysis of five prospective cohort studies". Experimental and Therapeutic Medicine 4.3 (2012): 481-486.
Chicago
Hou, L., Li, F., Zhou, Y., Nie, S., Su, L., Chen, P., Tan, W., Xu, D."Fish intake and risk of heart failure: A meta‑analysis of five prospective cohort studies". Experimental and Therapeutic Medicine 4, no. 3 (2012): 481-486. https://doi.org/10.3892/etm.2012.605