Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kümmell's disease with neurological deficits

  • Authors:
    • Guang-Quan Zhang
    • Yan-Zheng Gao
    • Jia Zheng
    • Jian-Ping Luo
    • Chao Tang
    • Shu-Lian Chen
    • Hong-Qiang Wang
    • Ke Liu
    • Rui-Gang Xie
  • View Affiliations

  • Published online on: November 26, 2012     https://doi.org/10.3892/etm.2012.833
  • Pages: 517-522
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Abstract

The aim of this study was to investigate the treatment of Kümmell's disease with neurological deficits and to determine whether intravertebral clefts are a pathognomonic sign of Kümmell's disease. A total of 17 patients who had initially been diagnosed with Kümmell's disease were admitted, one patient was excluded from this study. Posterior decompression and vertebroplasty for the affected vertebrae were conducted. Pedicle screw fixation and posterolateral bone grafts were performed one level above and one level below the affected vertebrae. Vertebral tissue was extracted for histopathological examination. The mean time of follow‑up was 22 months (range, 18 to 42 months). The anterior and middle vertebral heights were measured on standing lateral radiographs prior to surgery, one day postoperatively and at final follow‑up. The Cobb angle, the visual analog scale (VAS) and the Frankel classification were used to evaluate the effects of the surgery. The VAS, anterior and middle vertebral heights and the Cobb angle were improved significantly one day postoperatively and at the final follow-up compared with the preoperative examinations (P<0.05). No significant differences were observed between the one-day postoperative results and those at final follow-up (P>0.05). The neurological function of all patients was improved by at least one Frankel grade. All patients in this study exhibited intravertebral clefts, and postoperative pathology revealed bone necrosis. One patient (not included in this study) showed an intravertebral cleft, but the pathology report indicated a non-Hodgkin's lymphoma. The intravertebral cleft sign is not pathognomonic of Kümmell's disease. Posterior decompression with short-segment fixation and fusion combined with vertebroplasty is an effective treatment for Kümmell's disease with neurological deficits.
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February 2013
Volume 5 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zhang G, Gao Y, Zheng J, Luo J, Tang C, Chen S, Wang H, Liu K and Xie R: Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kümmell's disease with neurological deficits. Exp Ther Med 5: 517-522, 2013.
APA
Zhang, G., Gao, Y., Zheng, J., Luo, J., Tang, C., Chen, S. ... Xie, R. (2013). Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kümmell's disease with neurological deficits. Experimental and Therapeutic Medicine, 5, 517-522. https://doi.org/10.3892/etm.2012.833
MLA
Zhang, G., Gao, Y., Zheng, J., Luo, J., Tang, C., Chen, S., Wang, H., Liu, K., Xie, R."Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kümmell's disease with neurological deficits". Experimental and Therapeutic Medicine 5.2 (2013): 517-522.
Chicago
Zhang, G., Gao, Y., Zheng, J., Luo, J., Tang, C., Chen, S., Wang, H., Liu, K., Xie, R."Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kümmell's disease with neurological deficits". Experimental and Therapeutic Medicine 5, no. 2 (2013): 517-522. https://doi.org/10.3892/etm.2012.833