Correlation analysis of prognostic and pathological features of patients with chronic sinusitis and nasal polyps following endoscopic surgery

Tang,Jun; Liu,Sufu; Zhang,Liangyun; Chen,Weixiong; Shi,Sisi; Yu,Qingqing; Tang,Chao; Wang,Yuejian

doi:10.3892/etm.2013.1072

Correlation analysis of prognostic and pathological features of patients with chronic sinusitis and nasal polyps following endoscopic surgery

Authors:
- Jun Tang
- Sufu Liu
- Liangyun Zhang
- Weixiong Chen
- Sisi Shi
- Qingqing Yu
- Chao Tang
- Yuejian Wang
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Affiliations: Department of Otolaryngology - Head and Neck Surgery, The First People's Hospital of Foshan, Foshan, Guangdong 528000, P.R. China , Department of Otolaryngology - Head and Neck Surgery, Capital Medical University Affiliated Beijing Shijitan Hospital, Beijing 100038, P.R. China, Department of Pathology, The First People's Hospital of Foshan, Foshan, Guangdong 528000, P.R. China
Published online on: April 23, 2013 https://doi.org/10.3892/etm.2013.1072
Pages: 167-171

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Abstract

The aim of this study was to evaluate the therapeutic value of pathological indicators to predict the efficacy of endoscopic sinus surgery (ESS) in patients with chronic rhinosinusitis (CRS) with nasal polyps. A total of 53 patients with CRS with nasal polyps, who had undergone endoscopic surgery at least one year before, were surveyed for their clinical symptoms. Surgical specimen biopsies were consulted and related pathological indicators were measured. The association between the main symptoms of CRS with nasal polyps following ESS and pathological indicators were statistically analyzed. The main symptoms of patients with CRS with nasal polyps following ESS were nasal congestion, thick nasal discharge, rhinorrhea or sneezing. Goblet cells are associated with the symptoms of sneezing and thick nasal discharge, pathological gland formation is associated with dizziness, and the degree of tissue edema is associated with post-nasal discharge (P<0.05). Pathological indicators aid the prediction of the efficacy of nasal ESS in patients with CRS with nasal polyps.

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