Hypophosphatemic vitamin D-resistant osteomalacia: A case report
- Authors:
- Min Wang
- Xia Cao
- Bingzhen Cao
-
View Affiliations
Affiliations: Department of Neurology, Jinan Military General Hospital, Jinan, Shandong 250031, P.R. China
- Published online on: July 8, 2013 https://doi.org/10.3892/etm.2013.1209
-
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791-795
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Abstract
This study concerns the case of a 59-year-old woman who was admitted to hospital after experiencing systemic bone pain and muscle weakness for more than 2 years. The patient was diagnosed with numerous fractures via bone imaging emission computed tomography (ECT) and hypophosphatemia. Laboratory results showed a high alkaline phosphatase concentration. Thyroid nodules were visible on the thyroid and parathyroid glands during ultrasound examinations. However, no symptomatic or biochemical improvement was observed following a thyroid nodulectomy. The patient was administered large doses of neutral phosphate preparations, vitamin D3 and calcium. A gradual improvement in the condition of the patient was observed. For bone pain associated with multiple fractures in elderly patients, calcium and phosphorus metabolism disorders, and active vitamin D deficiency should be considered and an early diagnosis should be performed.
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