Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention

  • Authors:
    • Shao‑Peng Wang
    • Rong‑Chong Huang
    • Hao Zhu
    • Bo Zhang
    • Zhen-Guo  Zheng
    • Da Yin
    • Jun-Jie Wang
    • Xu‑Chen Zhou
  • View Affiliations

  • Published online on: July 11, 2013     https://doi.org/10.3892/etm.2013.1217
  • Pages: 811-815
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Abstract

At present, there is an increasing focus on stents that have a biodegradable polymer coating, rather than a permanent polymer coating. This is due to the fact that following the implantation of a drug‑eluting stent (DES) with a permanent polymer coating, the continued existence of the coating may result in a foreign body reaction and delayed re‑endothelialization. The aim of the present study was to evaluate the safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous (YINYI™) stent in real‑life percutaneous coronary intervention (PCI) for patients with coronary artery disease (CAD). A total of 686 YINYI™ stents were implanted in 404 patients with CAD in a PCI procedure and outpatient follow‑ups were performed 1, 6, 12 and 15 months subsequent to the PCI, respectively. The observation endpoints were major adverse cardiac events (MACEs), including cardiac death, non‑fatal myocardial infarction (MI), restenosis, target lesion revascularization, stent thrombosis and recurrence of angina pectoris. The average follow‑up time was 15 months. The results revealed that the cumulative incidences of MACEs were as follows: mortality, 0.99%; non‑fatal MI, 0.74%; restenosis, 4.0%; and target lesion revascularization, 2.7%. The results at the short‑ and long‑term clinical follow‑ups indicated that YINYI™ stents are effective and safe for use in PCI for patients with CAD.
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September 2013
Volume 6 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Wang SP, Huang RC, Zhu H, Zhang B, Zheng Z, Yin D, Wang J and Zhou XC: Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention. Exp Ther Med 6: 811-815, 2013.
APA
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D. ... Zhou, X. (2013). Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention. Experimental and Therapeutic Medicine, 6, 811-815. https://doi.org/10.3892/etm.2013.1217
MLA
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D., Wang, J., Zhou, X."Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention". Experimental and Therapeutic Medicine 6.3 (2013): 811-815.
Chicago
Wang, S., Huang, R., Zhu, H., Zhang, B., Zheng, Z., Yin, D., Wang, J., Zhou, X."Safety and efficacy of a non‑polymeric paclitaxel‑eluting microporous stent in real‑world percutaneous coronary intervention". Experimental and Therapeutic Medicine 6, no. 3 (2013): 811-815. https://doi.org/10.3892/etm.2013.1217