Strontium coating by electrochemical deposition improves implant osseointegration in osteopenic models

Liang,Yongqiang; Li,Haoyan; Xu,Jiang; Li,Xin; Li,Xinchang; Yan,Yuting; Qi,Mengchun; Hu,Min

doi:10.3892/etm.2014.2038

Strontium coating by electrochemical deposition improves implant osseointegration in osteopenic models

Authors:
- Yongqiang Liang
- Haoyan Li
- Jiang Xu
- Xin Li
- Xinchang Li
- Yuting Yan
- Mengchun Qi
- Min Hu
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Affiliations: College of Stomatology, Hebei United University, Tangshan, Hebei 063000, P.R. China, Department of Stomatology, People's Hospital of Tongchuan, Shaanxi 727000, P.R. China, Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China
Published online on: October 30, 2014 https://doi.org/10.3892/etm.2014.2038
Pages: 172-176

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Abstract

Osteopenia, a preclinical state of osteoporosis, restricts the application of adult orthodontic implant anchorage and tooth implantation. Strontium (Sr) is able to promote bone formation and inhibit bone absorption. The aim of the present study was to evaluate a new method for improving the success rate of dental implantation. In this study, an electrochemical deposition (ECD) method was used to prepare a Sr coating on a titanium implant. The coating composition was investigated by energy dispersive X‑ray spectroscopy and X‑ray diffraction, and the surface morphology of the coating was studied using scanning electron microscopy. A total of 24 Sprague‑Dawley rats received bilateral ovariectomy (OVX) and an additional 12 rats underwent a sham surgery. All rats were then implanted in the bilateral tibiae with titanium mini-implants with or without a Sr coating. The results of histological examination and a fluorescence double labeling assay showed strong new bone formation with a wider zone between the double labels, a higher rate of bone mineralization and better osseointegration in the OVX rats that received Sr‑coated implants compared with the OVX rats that received uncoated implants. The study indicates that Sr coatings are easily applied by an ECD method, and that Sr coatings have a promoting effect on implant osseointegration in animals with osteopenia.

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