Polycythemia vera associated with IgA nephropathy: A case report and literature review

  • Authors:
    • Hong Chen
    • Baohe Zhang
    • Mingxu Li
    • Ruilan Hu
    • Chunhua Zhou
  • View Affiliations

  • Published online on: June 11, 2015     https://doi.org/10.3892/etm.2015.2572
  • Pages: 555-560
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Abstract

A case of polycythemia vera (PV) associated with immunoglobulin A nephropathy (IgAN) in a 57‑year‑old man is described. The patient had a mild enlargement of the kidneys and elevated serum creatinine level, whereas the glomerular filtration rate was normal. Pathological observation under a light microscope showed mild mesangial hyperplasia. The urinary protein level was found to be positively correlated with changes in blood cell counts. After controlling blood pressure, anti‑platelet, hydroxyurea treatment, the patient's proteinuria decreased and renal function remained in the normal range. PV associated with renal disease is rare and generally considered to be associated with hypervolemia or high‑viscosity‑induced renal hyperperfusion and hyperfiltration. This is a rare case of PV associated with IgAN without a high filtration rate. A review of the clinical features of PV associated with renal disease from previous literature was also conducted. The histological results of the cases varied and included IgAN, focal segmental glomerulosclerosis and membranoproliferative glomerulonephritis.
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August-2015
Volume 10 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Chen H, Zhang B, Li M, Hu R and Zhou C: Polycythemia vera associated with IgA nephropathy: A case report and literature review. Exp Ther Med 10: 555-560, 2015.
APA
Chen, H., Zhang, B., Li, M., Hu, R., & Zhou, C. (2015). Polycythemia vera associated with IgA nephropathy: A case report and literature review. Experimental and Therapeutic Medicine, 10, 555-560. https://doi.org/10.3892/etm.2015.2572
MLA
Chen, H., Zhang, B., Li, M., Hu, R., Zhou, C."Polycythemia vera associated with IgA nephropathy: A case report and literature review". Experimental and Therapeutic Medicine 10.2 (2015): 555-560.
Chicago
Chen, H., Zhang, B., Li, M., Hu, R., Zhou, C."Polycythemia vera associated with IgA nephropathy: A case report and literature review". Experimental and Therapeutic Medicine 10, no. 2 (2015): 555-560. https://doi.org/10.3892/etm.2015.2572