Papillary tumor of the pineal region: A case report and review of the literature

Hua,Xiaomin; Yang,Ping; Zhang,Ming; Zhao,Yudan; Wang,Bin

doi:10.3892/etm.2015.2696

Papillary tumor of the pineal region: A case report and review of the literature

Authors:
- Xiaomin Hua
- Ping Yang
- Ming Zhang
- Yudan Zhao
- Bin Wang
View Affiliations

Affiliations: Department of Microbiology, Qingdao University Medical College, Qingdao, Shandong 266071, P.R. China, Department of Pathology, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China, Department of Anatomy, Qingdao University Medical College, Qingdao, Shandong 266071, P.R. China
Published online on: August 20, 2015 https://doi.org/10.3892/etm.2015.2696
Pages: 1375-1379
Copyright: © Hua et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Papillary tumor of the pineal region (PTPR) was first described as a distinct tumor entity in 2003 and was introduced into the World Health Organization classification of central nervous system tumors in 2007. This tumor is rare and, to the best of our knowledge, only 7 cases have been reported in children <16 years of age, while the youngest documented patient was a 15‑month‑old boy. The present study reported a case of PTPR in a 10‑year‑old girl who underwent magnetic resonance imaging and surgical resection of tumors. Histological and immunohistochemical staining results were presented. Patients with PTPR require long-term follow-up, and the patient of the present study has continued to do well, with no recurrence of the tumor at the 15-month follow-up examination. In addition, a review of the literature on this unusual neoplasm was performed, along with discussion of their differential diagnosis.

View Figures

View References

1	Jouvet A, Fauchon F, Liberski P, Saint-Pierre G, Didier-Bazes M, Heitzmann A, Delisle MB, Biassette HA, Vincent S, Mikol J, et al: Papillary tumor of the pineal region. Am J Surg Pathol. 27:505–512. 2003. View Article : Google Scholar : PubMed/NCBI
2	Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW and Kleihues P: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropatholo. 114:97–109. 2007. View Article : Google Scholar
3	Li J, Recinos PF, Orr BA, Burger PC, Jallo GI and Recinos VR: Papillary tumor of the pineal region in a 15-month-old boy. J Neurosurg Pediatr. 7:534–538. 2011.PubMed/NCBI
4	Montange MF, Vasiljevic A, Champier J and Jouvet A: Papillary tumor of the pineal region: Histopathological characterization and review of the literature. Neurochirurgie. 61:138–142. 2014. View Article : Google Scholar : PubMed/NCBI
5	Vandergriff C, Opatowsky M, O'Rourke B and Layton K: Papillary tumor of the pineal region. Proc (Bayl Univ Med Cent). 25:78–79. 2012.PubMed/NCBI
6	Bruce JN and Stein B: Pineal tumors. Neurosurg Clin N Am. 1:123–138. 1990.PubMed/NCBI
7	Kawahara I, Tokunaga Y, Yagi N, Iseki M, Abe K and Hayashi T: Papillary tumor of the pineal region. Neurol Med Chir (Tokyo). 47:568–571. 2007. View Article : Google Scholar : PubMed/NCBI
8	Rickard KA, Parker JR, Vitaz TW, Plaga AR, Wagner S and Parker JC Jr: Papillary Tumor of the Pineal Region: Two Case studies and a review of the literature. Ann Clin Lab Sci. 41:174–181. 2011.PubMed/NCBI
9	Inoue T, Kumabe T, Kanamori M, Sonoda Y, Watanabe M and Tominaga T: Papillary tumor of the pineal region: A case report. Brain Tumor Pathol. 25:85–90. 2008. View Article : Google Scholar : PubMed/NCBI
10	Boco T, Aalaei S, Musacchio M, Byrne R and Cochran E: Papillary tumor of the pineal region. Neuropathology. 28:87–92. 2008. View Article : Google Scholar : PubMed/NCBI
11	Junior GV, Dellaretti M, de Carvalho GT, Brandão RA, Mafra A and de Sousa AA: Papillary tumor of the pineal region. Brain Tumor Patholo. 28:329–334. 2011. View Article : Google Scholar
12	Chang AH, Fuller GN, Debnam JM, Karis JP, Coons SW, Ross JS and Dean BL: MR imaging of papillary tumor of the pineal region. AJNR Am J Neuroradio. 29:187–189. 2008. View Article : Google Scholar
13	Kawahara I, Tokunaga Y, Yagi N, Iseki M, Abe K and Hayashi T: Papillary tumor of the pineal region. Neurolo Med Chir (Tokyo). 47:568–571. 2007. View Article : Google Scholar
14	Sun IS, Kirollos R and Santarius T: No 5-ALA fluorescence seen in a recurrent papillary tumour of the pineal region (PTPR). Acta Neurochir (Wien). 157:215–216. 2015. View Article : Google Scholar : PubMed/NCBI
15	Poulgrain K, Gurgo R, Winter C, Ong B and Lau Q: Papillary tumour of the pineal region. J Clin Neurosci. 18:1007–1017. 2011. View Article : Google Scholar : PubMed/NCBI
16	Li J, Recinos PF, Orr BA, Burger PC, Jallo GI and Recinos VR: Papillary tumor of the pineal region in a 15-month-old boy. J Neurosurg Pediatr. 7:534–538. 2011.PubMed/NCBI
17	Santoro A, D'Elia A, Fazzolari B, Santoro F, Antonelli M, Giangaspero F, Brogna C, Lenzi J, Frati A and Salvati M: Four-year clinical and neuroradiological follow-up of a papillary tumor of the pineal region. Neurol Sci. 33:931–935. 2012. View Article : Google Scholar : PubMed/NCBI
18	Matyja E, Grajkowska W, Nauman P and Bonicki W: Histopathological patterns of papillary tumour of the pineal region. Folia Neuropathol. 49:181–190. 2011.PubMed/NCBI
19	Abela L, Rushing EJ, Ares C, Scheer I, Bozinov O, Boltshauser E and Grotzer MA: Pediatric papillary tumors of the pineal region: To observe or to treat following gross total resection? Childs Nerv Syst. 29:307–310. 2013. View Article : Google Scholar : PubMed/NCBI
20	Ishida A, Shibuya M, Komori T, Nobusawa S, Niimura K, Matsuo S and Hori T: Papillary tumor of the pineal region: A case involving isocitrate dehydrogenase (IDH) genotyping. Brain Tumor pathol. 30:45–49. 2013. View Article : Google Scholar : PubMed/NCBI
21	Magalhêes J, Rostad S, Foltz G, Pytel P and Rodriguez FJ: Cellular pleomorphism in papillary tumors of the pineal region. Brain Tumor Pathol. 30:93–98. 2013. View Article : Google Scholar : PubMed/NCBI
22	Patel SK, Tomei KL, Christiano LD, Baisre A and Liu JK: Complete regression of papillary tumor of the pineal region after radiation therapy: Case report and review of the literature. J Neurooncol. 107:427–434. 2012. View Article : Google Scholar : PubMed/NCBI
23	Vandergriff C, Opatowsky M, O'Rourke B and Layton K: Papillary tumor of the pineal region. Proc (Bayl Univ Med Cent). 25:78–79. 2012.PubMed/NCBI
24	Koziarski A, Grala B and Skrobowska E: Papillary tumor of the pineal region. Report of two cases and literature review. Neurol Neurochir Pol. 48:356–362. 2014.PubMed/NCBI
25	Rosa Junior M, da Rocha AJ, Zanon da Silva A and Rosemberg S: Papillary tumor of the pineal region: MR Signal intensity correlated to histopathology. Case Rep Neurol Med. 2015:3150952015.PubMed/NCBI