Clinical and radiographic observations from four patients with primary hepatic lymphoma

Hu,Hui‑Juan; Qu,Yan‑Juan; Tian,Zhi‑Xiong; Zhang,Zai‑Peng

doi:10.3892/etm.2015.2940

Clinical and radiographic observations from four patients with primary hepatic lymphoma

Authors:
- Hui‑Juan Hu
- Yan‑Juan Qu
- Zhi‑Xiong Tian
- Zai‑Peng Zhang
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Affiliations: Department of Computed Tomography, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China
Published online on: December 16, 2015 https://doi.org/10.3892/etm.2015.2940
Pages: 381-386
Copyright: © Hu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the present study was to delineate the radiographic and clinical features of primary hepatic lymphoma (PHL). Four histopathologically confirmed cases of PHL were analyzed with respect to the radiological, clinical and pathological characteristics. The main clinical manifestations included upper right quadrant pain and lymphoma‑associated B symptoms, such as fever, night sweating and weight loss. All the patients had elevated serum levels of lactate dehydrogenase. Furthermore, all the patients underwent plain and enhanced computed tomography examinations, which identified low‑density lesions without marked enhancement. Solitary masses were observed in two cases, while multiple focal lesions were noted in one case and diffuse multi‑speckled nodules were observed in one case. Two patients underwent abdominal magnetic resonance imaging, which revealed lesions that were hyperintense on T1‑weighted imaging (WI) scans and hypointense on T2WI scans, and exhibited slight to moderate enhancement with a dynamic contrast‑enhanced protocol. In one case, vessels were visible within the lesion. Therefore, the present study concluded that PHL is a rare condition that exhibits non‑specific clinical and radiological features. A combination of imaging results and clinical manifestations can be used to facilitate a diagnosis of PHL.

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