Open Access

Clinicopathologic characteristics of Weneger's granulomatosis: A report of three cases

  • Authors:
    • Li-Yong Gao
    • Jin Ding
    • Li Zhao
  • View Affiliations

  • Published online on: February 3, 2016     https://doi.org/10.3892/etm.2016.3046
  • Pages: 1340-1344
  • Copyright: © Gao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Weneger's granulomatosis (WG) is a rare auto­immune disease affecting a number of organs, including lungs and kidney. Although all age groups may be affected, the peak incidence occurs for individuals aged 30-50 years, with a slightly increased prevalence in males. In the current study, we present three cases of WG to describe clinical and pathological characteristics of this disease. Three patients with WG were assessed for clinical and pathological characteristics, and typical morphological findings using computerized tomography. Clinical manifestations included vasculitis, tissue necrosis, and the formation of granuloma. Following a large dose of glucocorticoid hormone treatment, the symptoms were successfully relieved in all three patients. In conclusion, the diagnosis of WG is dependent on pathological examination in combination with appropriate clinical and imaging data, and immuno­staining with anti-neutrophil cytoplasmic antibody.
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April-2016
Volume 11 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Gao L, Ding J and Zhao L: Clinicopathologic characteristics of Weneger's granulomatosis: A report of three cases. Exp Ther Med 11: 1340-1344, 2016.
APA
Gao, L., Ding, J., & Zhao, L. (2016). Clinicopathologic characteristics of Weneger's granulomatosis: A report of three cases. Experimental and Therapeutic Medicine, 11, 1340-1344. https://doi.org/10.3892/etm.2016.3046
MLA
Gao, L., Ding, J., Zhao, L."Clinicopathologic characteristics of Weneger's granulomatosis: A report of three cases". Experimental and Therapeutic Medicine 11.4 (2016): 1340-1344.
Chicago
Gao, L., Ding, J., Zhao, L."Clinicopathologic characteristics of Weneger's granulomatosis: A report of three cases". Experimental and Therapeutic Medicine 11, no. 4 (2016): 1340-1344. https://doi.org/10.3892/etm.2016.3046