Clinicopathological significance of forkhead box protein A1 in breast cancer: A meta-analysis

  • Authors:
    • Keli He
    • Hui Zeng
    • Xianqun Xu
    • Anling Li
    • Qing Cai
    • Xinghua Long
  • View Affiliations

  • Published online on: April 6, 2016     https://doi.org/10.3892/etm.2016.3229
  • Pages: 2525-2530
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Abstract

The aim of the present study was to investigate the associations between the expression of forkhead box protein A1 (FOXA1) and differential clinicopathological characteristics in breast cancer using a meta‑analysis method. Eligible studies that investigated the correlation between FOXA1 expression and the clinical characteristics of breast cancer were collected through searching numerous databases, including PubMed, EMBASE, the Chinese National Knowledge Infrastructure and the VIP database. In total, eight studies were included in the meta‑analysis. Following a systematic analysis, the expression of FOXA1 was found to be significantly associated with the estrogen receptor α status, the progesterone receptor status, lymph node metastasis and the histological grade in breast cancer. However, no statistically significant association was observed between FOXA1 expression and the human epidermal growth factor receptor-2 status in breast cancer patients.
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June-2016
Volume 11 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
He K, Zeng H, Xu X, Li A, Cai Q and Long X: Clinicopathological significance of forkhead box protein A1 in breast cancer: A meta-analysis. Exp Ther Med 11: 2525-2530, 2016.
APA
He, K., Zeng, H., Xu, X., Li, A., Cai, Q., & Long, X. (2016). Clinicopathological significance of forkhead box protein A1 in breast cancer: A meta-analysis. Experimental and Therapeutic Medicine, 11, 2525-2530. https://doi.org/10.3892/etm.2016.3229
MLA
He, K., Zeng, H., Xu, X., Li, A., Cai, Q., Long, X."Clinicopathological significance of forkhead box protein A1 in breast cancer: A meta-analysis". Experimental and Therapeutic Medicine 11.6 (2016): 2525-2530.
Chicago
He, K., Zeng, H., Xu, X., Li, A., Cai, Q., Long, X."Clinicopathological significance of forkhead box protein A1 in breast cancer: A meta-analysis". Experimental and Therapeutic Medicine 11, no. 6 (2016): 2525-2530. https://doi.org/10.3892/etm.2016.3229