Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

  • Authors:
    • Yi‑Wei Zhang
    • Ji‑Hua Zhong
    • Xiao‑Long Chen
    • Fei Xiao
    • Fang‑Yuan Chen
  • View Affiliations

  • Published online on: April 15, 2016     https://doi.org/10.3892/etm.2016.3259
  • Pages: 319-322
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Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a clinically aggressive tumor, which frequently presents as cutaneous lesions and subsequently progresses to bone marrow (BM) involvement and leukemic dissemination. BPDCN is a rare entity that belongs in the same class as acute myeloid leukemia‑associated precursor neoplasms, according to the 2008 World Health Organization classification. The present study reported the case of a 26‑year‑old female who presented with evident thrombocytopenia, leukocytosis and anemia, but without skin lesions. The results of peripheral blood, BM smear and BM biopsy examinations detected numerous blastic or abnormal cells. In addition, flow cytometric analysis of BM demonstrated the presence of plasmacytoid dendritic cell‑neoplastic precursor cells (CD4+, CD56+, CD123+, CD304+ and human leukocyte antigen‑DR+ phenotype).
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July-2016
Volume 12 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zhang YW, Zhong JH, Chen XL, Xiao F and Chen FY: Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review. Exp Ther Med 12: 319-322, 2016.
APA
Zhang, Y., Zhong, J., Chen, X., Xiao, F., & Chen, F. (2016). Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review. Experimental and Therapeutic Medicine, 12, 319-322. https://doi.org/10.3892/etm.2016.3259
MLA
Zhang, Y., Zhong, J., Chen, X., Xiao, F., Chen, F."Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review". Experimental and Therapeutic Medicine 12.1 (2016): 319-322.
Chicago
Zhang, Y., Zhong, J., Chen, X., Xiao, F., Chen, F."Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review". Experimental and Therapeutic Medicine 12, no. 1 (2016): 319-322. https://doi.org/10.3892/etm.2016.3259