Accuracy of contrast-enhanced ultrasound compared with conventional ultrasound in acute pancreatitis: Diagnosis and complication monitoring

Cai,Diming; Parajuly,Shyam Sundar; Wang,Huiyao; Wang,Xiaoling; Ling,Wenwu; Song,Bin; Li,Yongzhong; Luo,Yan

doi:10.3892/etm.2016.3760

Accuracy of contrast-enhanced ultrasound compared with conventional ultrasound in acute pancreatitis: Diagnosis and complication monitoring

Authors:
- Diming Cai
- Shyam Sundar Parajuly
- Huiyao Wang
- Xiaoling Wang
- Wenwu Ling
- Bin Song
- Yongzhong Li
- Yan Luo
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Affiliations: Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Training Department of Resident Doctor, West China School of Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Department of Operations Management, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
Published online on: September 30, 2016 https://doi.org/10.3892/etm.2016.3760
Pages: 3189-3194
Copyright: © Cai et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Contrast-enhanced ultrasound (CEUS) has been used for diagnosing acute pancreatitis (AP), particularly severe acute pancreatitis (SAP). However, the diagnostic difference between CEUS and conventional ultrasonography (CUS) for AP and SAP has not been reported. The aim of the present study was to investigate the diagnostic accuracy of CUS and CEUS for AP. A total of 196 patients clinically diagnosed with AP were selected. All patients underwent CUS, CEUS and contrast‑enhanced computed tomography (CECT) within 72 h. CECT was considered the gold standard. Pancreatic size, peripancreatic fluid collection (PPFC) and splenic vessel complications were the variables observed by CUS and CEUS. The differences in the variables among the three methods were analyzed using the χ2 test and statistical analysis software. Significant differences in pancreatic size, PPFC and splenic vessel complications in AP were observed between CEUS and CUS (P<0.05). χ2 test results indicated that CEUS significantly differed from CUS in terms of having a higher diagnostic accuracy for AP and SAP (P<0.05). The results indicate that CEUS is a reliable method for the diagnosis and monitoring of AP and SAP, and may be substituted for CECT.

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