Open Access

Diagnostic accuracy of coronary CT angiography combined with dual-energy myocardial perfusion imaging for detection of myocardial infarction

  • Authors:
    • Ruijuan Han
    • Kai Sun
    • Bin Lu
    • Ruiping Zhao
    • Kuncheng Li
    • Xinchun Yang
  • View Affiliations

  • Published online on: May 22, 2017     https://doi.org/10.3892/etm.2017.4485
  • Pages: 207-213
  • Copyright: © Han et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the present study was to evaluate the diagnostic accuracy of second generation dual‑energy computed tomography (DECT) myocardial perfusion imaging for the detection of myocardial infarction (MI) in patients with suspected MI. In total, 56 patients underwent DECT. Among those, 40 patients had MI that was detected by catheter coronary angiography and cardiac troponin I elevation and evolution of acute MI detected by electrocardiogram changes. The diagnostic accuracy, including the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for the detection of MI were evaluated, as well as the coronary image quality of coronary artery and radiation dose. The sensitivity, specificity, PPV and NPV for the detection of MI were 95.0, 97.0, 86.4 and 98.9%, respectively. Moreover, the image quality was rated excellent (score 1) in 90.2% (515/571), good (score 2) in 6.5% (37/571), adequate (score 3) in 1.9% (11/571) and non‑diagnostic (score 4) in 1.4% (8/571) of the coronary segments. The effective radiation dose was on average 6.1±1.5 mSv (3.1‑10.9 mSv). Therefore, combined DE iodine maps and coronary CT angiography using the DECT may provide a high diagnostic accuracy for detecting MI with lower radiation exposure in patients with suspected MI.
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July-2017
Volume 14 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Han R, Sun K, Lu B, Zhao R, Li K and Yang X: Diagnostic accuracy of coronary CT angiography combined with dual-energy myocardial perfusion imaging for detection of myocardial infarction. Exp Ther Med 14: 207-213, 2017.
APA
Han, R., Sun, K., Lu, B., Zhao, R., Li, K., & Yang, X. (2017). Diagnostic accuracy of coronary CT angiography combined with dual-energy myocardial perfusion imaging for detection of myocardial infarction. Experimental and Therapeutic Medicine, 14, 207-213. https://doi.org/10.3892/etm.2017.4485
MLA
Han, R., Sun, K., Lu, B., Zhao, R., Li, K., Yang, X."Diagnostic accuracy of coronary CT angiography combined with dual-energy myocardial perfusion imaging for detection of myocardial infarction". Experimental and Therapeutic Medicine 14.1 (2017): 207-213.
Chicago
Han, R., Sun, K., Lu, B., Zhao, R., Li, K., Yang, X."Diagnostic accuracy of coronary CT angiography combined with dual-energy myocardial perfusion imaging for detection of myocardial infarction". Experimental and Therapeutic Medicine 14, no. 1 (2017): 207-213. https://doi.org/10.3892/etm.2017.4485