Diffusion‑weighted whole‑body magnetic resonance imaging with background body signal suppression/T2 image fusion for the diagnosis of acute cholecystitis

Tomizawa,Minoru; Shinozaki,Fuminobu; Tanaka,Satomi; Sunaoshi,Takafumi; Kano,Daisuke; Sugiyama,Eriko; Shite,Misaki; Haga,Ryouta; Fukamizu,Yoshiya; Fujita,Toshiyuki; Kagayama,Satoshi; Hasegawa,Rumiko; Shirai,Yoshinori; Motoyoshi,Yasufumi; Sugiyama,Takao; Yamamoto,Shigenori; Ishige,Naoki

doi:10.3892/etm.2017.4561

Diffusion‑weighted whole‑body magnetic resonance imaging with background body signal suppression/T2 image fusion for the diagnosis of acute cholecystitis

Authors:
- Minoru Tomizawa
- Fuminobu Shinozaki
- Satomi Tanaka
- Takafumi Sunaoshi
- Daisuke Kano
- Eriko Sugiyama
- Misaki Shite
- Ryouta Haga
- Yoshiya Fukamizu
- Toshiyuki Fujita
- Satoshi Kagayama
- Rumiko Hasegawa
- Yoshinori Shirai
- Yasufumi Motoyoshi
- Takao Sugiyama
- Shigenori Yamamoto
- Naoki Ishige
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Affiliations: Department of Gastroenterology, National Hospital Organization of Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Radiology, National Hospital Organization of Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Surgery, National Hospital Organization of Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Neurology, National Hospital Organization of Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Rheumatology, National Hospital Organization of Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Pediatrics, National Hospital Organization of Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan, Department of Neurosurgery, National Hospital Organization of Shimoshizu Hospital, Yotsukaido, Chiba 284‑0003, Japan
Published online on: June 8, 2017 https://doi.org/10.3892/etm.2017.4561
Pages: 730-734

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Abstract

Prompt and accurate diagnosis is critical in the treatment of acute cholecystitis. Diffusion‑weighted whole‑body magnetic resonance imaging with background body signal suppression/T2 image fusion (DWIBS/T2) identifies areas with high signal intensity, corresponding to inflammation. In the present study, the records and images of patients with acute cholecystitis who underwent DWIBS/T2 between January 2013 and March 2014 were retrospectively analyzed. A total of 11 patients with acute cholecystitis were enrolled. In one patient, DWIBS/T2 identified a thickened wall and high signal intensity, with high signal intensity in the pericholecystic space that suggested localized peritonitis. Positive DWIBS/T2 results indicating acute cholecystitis were obtained in 10/11 patients, with a sensitivity of 90.9%. In addition, wall thickening and high signal intensity were absent in DWIBS/T2 images when wall thickening was not detected by computed tomography. Wall thickening and high signal intensity was attenuated when patients with acute cholecystitis were clinically treated. These data suggest that a thickened gallbladder wall and high signal intensity are indicative of acute cholecystitis and that DWIBS/T2 may be a useful technique in evaluating the severity of acute cholecystitis.

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