Open Access

Stent retriever thrombectomy combined with local thrombolytic therapy for cerebral venous sinus thrombosis: A case report

Corrigendum in: /10.3892/etm.2017.5676

  • Authors:
    • Chengwei Chen
    • Qiujing Wang
    • Xifeng Li
    • Ziming Lu
    • Jian He
    • Qinrui Fang
    • Xunchang Ke
    • Chuanzhi Duan
    • Tielin Li
  • View Affiliations

  • Published online on: August 28, 2017     https://doi.org/10.3892/etm.2017.5043
  • Pages: 3961-3970
  • Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The present study reports the effect of successful treatment of cerebral venous sinus thrombosis (CVST) with stent retriever thrombectomy combined with local thrombolytic therapy. Medical records of 29 patients were retrospectively analyzed following a diagnosis of CVST with magnetic resonance venography (MRV) or digital subtraction angiography (DSA). Systemic anticoagulation was the initial treatment in all patients following admission. In group A, stent retriever thrombectomy combined with local thrombolytic therapy was performed on 14 patients who met the criteria of endovascular therapy. Stent‑assisted angioplasty was also performed when patients presented with venous sinus stenosis. A total of 15 patients in group B received systemic anticoagulant treatment. Subsequently, warfarin was administered orally for 3 to 12 months as a continuous anticoagulant therapy. International normalized ratio was monitored when patients were receiving anticoagulant therapy. Additionally, clinical presentation, decision to escalate therapy, recanalization, Glasgow Coma Scale, modified Rankin Scale (mRS) and the clinical outcome was assessed. A total of 14 patients (9 female patients, 5 male patients), with ages ranging from 17 to 57 years, met the criteria of endovascular therapy. The clinical symptoms of 12 patients had improved after receiving endovascular therapy and only 2 patients suffered from intracranial hemorrhage following the procedure. Complete recanalization of venous sinus was exhibited in 10/14 (71.4%) patients in group A when compared with 1/15 (6.7%) patients in group B. mRS were improved in the 12‑month follow‑up in groups A and B when compared with that at admission. In the present study, patients with acute CVST treated with stent retriever thrombectomy combined with local thrombolytic therapy had a favorable outcome. To conclude, the present study provides a treatment option in treating CVST, particularly for patients that present with evident cortical venous outflow stasis or deteriorate neurology, despite appropriate anticoagulant therapy.
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November-2017
Volume 14 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Chen C, Wang Q, Li X, Lu Z, He J, Fang Q, Ke X, Duan C and Li T: Stent retriever thrombectomy combined with local thrombolytic therapy for cerebral venous sinus thrombosis: A case report Corrigendum in /10.3892/etm.2017.5676. Exp Ther Med 14: 3961-3970, 2017
APA
Chen, C., Wang, Q., Li, X., Lu, Z., He, J., Fang, Q. ... Li, T. (2017). Stent retriever thrombectomy combined with local thrombolytic therapy for cerebral venous sinus thrombosis: A case report Corrigendum in /10.3892/etm.2017.5676. Experimental and Therapeutic Medicine, 14, 3961-3970. https://doi.org/10.3892/etm.2017.5043
MLA
Chen, C., Wang, Q., Li, X., Lu, Z., He, J., Fang, Q., Ke, X., Duan, C., Li, T."Stent retriever thrombectomy combined with local thrombolytic therapy for cerebral venous sinus thrombosis: A case report Corrigendum in /10.3892/etm.2017.5676". Experimental and Therapeutic Medicine 14.5 (2017): 3961-3970.
Chicago
Chen, C., Wang, Q., Li, X., Lu, Z., He, J., Fang, Q., Ke, X., Duan, C., Li, T."Stent retriever thrombectomy combined with local thrombolytic therapy for cerebral venous sinus thrombosis: A case report Corrigendum in /10.3892/etm.2017.5676". Experimental and Therapeutic Medicine 14, no. 5 (2017): 3961-3970. https://doi.org/10.3892/etm.2017.5043