Ocular pulse amplitude in different types of glaucoma using dynamic contour tonometry: Diagnosis and follow‑up of glaucoma

Cheng,Lingyan; Ding,Yuzhi; Duan,Xuanchu; Wu,Zhifeng

doi:10.3892/etm.2017.5074

Ocular pulse amplitude in different types of glaucoma using dynamic contour tonometry: Diagnosis and follow‑up of glaucoma

Authors:
- Lingyan Cheng
- Yuzhi Ding
- Xuanchu Duan
- Zhifeng Wu
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Affiliations: Department of Ophthalmology, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, Jiangsu 214000, P.R. China, Department of Ophthalmology, Zhongda Hospital, Medical School of Southeast University, Nanjing, Jiangsu 210009, P.R. China, Department of Ophthalmology, Xiangya No. 2 Hospital Affiliated to Central South University, Changsha, Hunan 410008, P.R. China
Published online on: August 30, 2017 https://doi.org/10.3892/etm.2017.5074
Pages: 4148-4152
Copyright: © Cheng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the present study was to compare the ocular pulse amplitude (OPA) in patients with different types of glaucoma using dynamic contour tonometry (DCT), to evaluate ocular and systemic factors associated with the OPA and to verify whether OPA measured by DCT is an independent predictor for glaucoma diagnosis. A total of 217 eyes of 217 participants in the following five groups were included in this cross‑sectional study: Chronic angle closure glaucoma (CACG), primary open angle glaucoma, normal tension glaucoma (NTG), suspected open angle glaucoma (SOAG) and normal control (NC). The following tests were simultaneously performed during a single visit: Intra‑ocular pressure (IOP), OPA, cup‑to‑disk (C/D) ratio, mean damage (MD) and loss variance (LV). OPAs were compared in each group. The association between OPA and IOP, age, C/D ratio, MD and LV was detected. OPA analysis prior to and after trabeculectomy was also performed to assess its prognostic value. Among the 217 individuals, the OPA was consistent with the IOP, both measured by DCT, along with the MD and LV. Patients with CACG and SOAG had higher OPA values than those with NTG and normal controls. Compared with patients aged >30 years, the OPA was significantly lower in younger patients, while they may not have been affected by different C/D ratios. After trabeculectomy, the OPA had significantly decreased compared with the values prior to surgery. In conclusion, the present study showed that the OPA is correlated with the IOP determined by DCT. CACG and SOAG patients had higher OPA values than patients with other types of glaucoma. OPA measured by DCT may be a predictor for glaucoma diagnosis and prognosis.

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