Kasabach‑Merritt syndrome combined with hypercalcemia: A case report

Zou,Runying; Peng,Fang; Yu,Tian; Zeng,Saizhen; You,Yalan; Chen,Keke; Zou,Hui; Tian,Xin; Zhu,Chengguang; He,Xiangling

doi:10.3892/etm.2017.5332

Kasabach‑Merritt syndrome combined with hypercalcemia: A case report

Authors:
- Runying Zou
- Fang Peng
- Tian Yu
- Saizhen Zeng
- Yalan You
- Keke Chen
- Hui Zou
- Xin Tian
- Chengguang Zhu
- Xiangling He
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Affiliations: Department of Hematology and Oncology of Children's Medical Center, Hunan Provincial People's Hospital, Changsha, Hunan 410005, P.R. China
Published online on: October 18, 2017 https://doi.org/10.3892/etm.2017.5332
Pages: 6164-6168

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Abstract

The present case report presented the diagnosis and treatment course of an infant diagnosed with Kasabach‑Merritt syndrome (KMS) combined with hypercalcemia (HC). A 35‑day‑old infant with swelling on the upper right arm for >1 month and thrombocytopenia for 1 day was admitted to Hunan Provincial People's Hospital (Changsha, China) and a series of treatments, including γ‑globulin impact, heparin anticoagulation, platelet transfusion, supplement of cryoprecipitate and fibrinogen following heparinization and inhabitation of vascular endothelial cell proliferation by propranolol, were performed. At 2 months after the initial admission to the hospital, surgery was conducted and the hemangioma was removed through pipeline arteriosclerosis embolization when the patient was hospitalized again with symptoms of vomiting and atrophy accompanied by HC. The level of blood calcium reduced to normal following surgery. Cases of KMS combined with HC are extremely rare and the most effective way to treat such cases is surgical resection of the hemangioma.

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