Goodpasture's syndrome in early pregnancy: A case report

Qin,Juan; Song,Guolin; Liu,Qin

doi:10.3892/etm.2017.5425

Goodpasture's syndrome in early pregnancy: A case report

Authors:
- Juan Qin
- Guolin Song
- Qin Liu
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Affiliations: Guizhou Maternal and Child Health Hospital, Guiyang, Guizhou 550000, P.R. China, Traditional Chinese Medicine Hospital of Guizhou, Guiyang, Guizhou 550000, P.R. China
Published online on: November 1, 2017 https://doi.org/10.3892/etm.2017.5425
Pages: 407-411

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Abstract

Goodpasture's syndrome (GPS) presenting during pregnancy is extremely rare and patients exhibiting hemoptysis and renal dysfunction in early pregnancy are uncommon. The present study reports the case of a 17‑year‑old diagnosed with GPS during the thirteenth week of pregnancy. Prompt recognition and immediate treatment (steroids and plasma exchange) was initiated. Renal function normalized following treatment and anti‑GBM antibody became negative during hospital stay. However, due to irregular follow‑up, the patient eventually succumbed. The case highlights that the current treatment plan for GPS should be revised to improve the outcome of pregnancy. In addition, it determines how important it is for obstetricians to consider whether a pregnancy should be terminated to improve the chances of survival of pregnant patients with GPS.

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