1
|
Ferlay J, Soerjomataram I, Dikshit R, Eser
S, Mathers C, Rebelo M, Parkin DM, Forman D and Bray F: Cancer
incidence and mortality worldwide: Sources, methods and major
patterns in GLOBOCAN 2012. Int J Cancer. 136:E359–E386. 2015.
View Article : Google Scholar : PubMed/NCBI
|
2
|
Sullivan I and Planchard D: ALK inhibitors
in non-small cell lung cancer: The latest evidence and
developments. Ther Adv Med Oncol. 8:32–47. 2016. View Article : Google Scholar : PubMed/NCBI
|
3
|
Luque M, Díez FJ and Disdier C: Optimal
sequence of tests for the mediastinal staging of non-small cell
lung cancer. BMC Med Inform Decis Mak. 16:92016. View Article : Google Scholar : PubMed/NCBI
|
4
|
Kawasaki K, Sato Y, Suzuki Y, Saito H,
Nomura Y and Yoshida Y: Prognostic factors for surgically resected
N2 non-small cell lung cancer. Ann Thorac Cardiovasc Surg.
21:217–222. 2015. View Article : Google Scholar : PubMed/NCBI
|
5
|
Hsu YL, Kuo PL and Lin CC: Proliferative
inhibition, cell-cycle dysregulation, and induction of apoptosis by
ursolic acid in human non-small cell lung cancer A549 cells. Life
Sci. 75:2303–2316. 2004. View Article : Google Scholar : PubMed/NCBI
|
6
|
Arai Y, Watanabe S, Kimira M, Shimoi K,
Mochizuki R and Kinae N: Dietary intakes of flavonols, flavones and
isoflavones by Japanese women and the inverse correlation between
quercetin intake and plasma LDL cholesterol concentration. J Nutr.
130:2243–2250. 2000.PubMed/NCBI
|
7
|
Haddad AQ, Venkateswaran V, Viswanathan L,
Teahan SJ, Fleshner NE and Klotz LH: Novel antiproliferative
flavonoids induce cell cycle arrest in human prostate cancer cell
lines. Prostate Cancer Prostatic Dis. 9:68–76. 2006. View Article : Google Scholar : PubMed/NCBI
|
8
|
Suh Y, Afaq F, Khan N, Johnson JJ, Khusro
FH and Mukhtar H: Fisetin induces autophagic cell death through
suppression of mTOR signaling pathway in prostate cancer cells.
Carcinogenesis. 31:1424–1433. 2010. View Article : Google Scholar : PubMed/NCBI
|
9
|
Pal HC, Sharma S, Elmets CA, Athar M and
Afaq F: Fisetin inhibits growth, induces G2/M arrest and apoptosis
of human epidermoid carcinoma A431 cells: Role of mitochondrial
membrane potential disruption and consequent caspases activation.
Exp Dermatol. 22:470–475. 2013. View Article : Google Scholar : PubMed/NCBI
|
10
|
Suh Y, Afaq F, Johnson JJ and Mukhtar H: A
plant flavonoid fisetin induces apoptosis in colon cancer cells by
inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways.
Carcinogenesis. 30:300–307. 2009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Khan N, Asim M, Afaq F, Abu Zaid M and
Mukhtar H: A novel dietary flavonoid fisetin inhibits androgen
receptor signaling and tumor growth in athymic nude mice. Cancer
Res. 68:8555–8563. 2008. View Article : Google Scholar : PubMed/NCBI
|
12
|
Khan N, Afaq F, Syed DN and Mukhtar H:
Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle
arrest in human prostate cancer LNCaP cells. Carcinogenesis.
29:1049–1056. 2008. View Article : Google Scholar : PubMed/NCBI
|
13
|
Chen YC, Shen SC, Lee WR, Lin HY, Ko CH,
Shih CM and Yang LL: Wogonin and fisetin induction of apoptosis
through activation of caspase 3 cascade and alternative expression
of p21 protein in hepatocellular carcinoma cells SK-HEP-1. Arch
Toxicol. 76:351–359. 2002. View Article : Google Scholar : PubMed/NCBI
|
14
|
Maher P, Akaishi T and Abe K: Flavonoid
fisetin promotes ERK-dependent long-term potentiation and enhances
memory. Proc Natl Acad Sci USA. 103:pp. 16568–16573. 2006;
View Article : Google Scholar : PubMed/NCBI
|
15
|
Hou DX, Fukuda M, Johnson JA, Miyamori K,
Ushikai M and Fujii M: Fisetin induces transcription of NADPH:
Quinone oxidoreductase gene through an antioxidant responsive
element-involved activation. Int J Oncol. 18:1175–1179.
2001.PubMed/NCBI
|
16
|
Haddad AQ, Venkateswaran V, Viswanathan L,
Teahan SJ, Fleshner NE and Klotz LH: Novel antiproliferative
flavonoids induce cell cycle arrest in human prostate cancer cell
lines. Prostate Cancer Prostatic Dis. 9:68–76. 2006. View Article : Google Scholar : PubMed/NCBI
|
17
|
Chen YC, Shen SC, Lee WR, Lin HY, Ko CH,
Shih CM and Yang LL: Wogonin and fisetin induction of apoptosis
through activation of caspase 3 cascade and alternative expression
of p21 protein in hepatocellular carcinoma cells SK-HEP-1. Arch
Toxicol. 76:351–359. 2002. View Article : Google Scholar : PubMed/NCBI
|
18
|
Lu H, Chang DJ, Baratte B, Meijer L and
Schulze-Gahmen U: Crystal structure of a human cyclin-dependent
kinase 6 complex with a flavonol inhibitor, fisetin. J Med Chem.
48:737–743. 2005. View Article : Google Scholar : PubMed/NCBI
|
19
|
Lee WR, Shen SC, Lin HY, Hou WC, Yang LL
and Chen YC: Wogonin and fisetin induce apoptosis in human
promyeloleukemic cells, accompanied by a decrease of reactive
oxygen species, and activation of caspase 3 and Ca(2+)-dependent
endonuclease. Biochem Pharmacol. 63:225–236. 2002. View Article : Google Scholar : PubMed/NCBI
|
20
|
Yao K, Zhang L, Zhang Y, Ye P and Zhu N:
The flavonoid, fisetin, inhibits UV radiation-induced oxidative
stress and the activation of NF-kappaB and MAPK signaling in human
lens epithelial cells. Mol Vis. 14:1865–1871. 2008.PubMed/NCBI
|
21
|
Murtaza I, Adhami VM, Hafeez BB, Saleem M
and Mukhtar H: Fisetin, a natural flavonoid, targets chemoresistant
human pancreatic cancer AsPC-1 cells through DR3-mediated
inhibition of NF-kappaB. Int J Cancer. 125:2465–2473. 2009.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Kim SC, Kang SH, Jeong SJ and Kim SH, Ko
HS and Kim SH: Inhibition of c-Jun N-terminal kinase and nuclear
factor κB pathways mediates fisetin-exerted anti-inflammatory
activity in lipopolysccharide-treated RAW264. 7 cells.
Immunopharmacol Immunotoxicol. 34:645–650. 2012. View Article : Google Scholar : PubMed/NCBI
|
23
|
Goh FY, Upton N, Guan S, Cheng C,
Shanmugam MK, Sethi G, Leung BP and Wong WF: Fisetin, a bioactive
flavonol, attenuates allergic airway inflammation through negative
regulation of NF-κB. Eur J Pharmacol. 679:109–116. 2012. View Article : Google Scholar : PubMed/NCBI
|
24
|
Léotoing L, Wauquier F, Guicheux J,
Miot-Noirault E, Wittrant Y and Coxam V: The polyphenol fisetin
protects bone by repressing NF-κB and MKP-1-dependent signaling
pathways in osteoclasts. PLoS One. 8:e683882013. View Article : Google Scholar : PubMed/NCBI
|
25
|
Liao YC, Shih YW, Chao CH, Lee XY and
Chiang TA: Involvement of the ERK signaling pathway in fisetin
reduces invasion and migration in the human lung cancer cell line
A549. J Agric Food Chem. 57:8933–8941. 2009. View Article : Google Scholar : PubMed/NCBI
|
26
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Lin R, Maeda S, Liu C, Karin M and
Edgington TS: A large noncoding RNA is a marker for murine
hepatocellular carcinomas and a spectrum of human carcinomas.
Oncogene. 26:851–858. 2007. View Article : Google Scholar : PubMed/NCBI
|
28
|
Li S, Dong P, Wang J, Zhang J, Gu J, Wu X,
Wu W, Fei X, Zhang Z, Wang Y, et al: Icariin, a natural flavonol
glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via
a ROS/JNK-dependent mitochondrial pathway. Cancer Lett.
298:222–230. 2010. View Article : Google Scholar : PubMed/NCBI
|
29
|
Pal HC, Sharma S, Strickland LR, Katiyar
SK, Ballestas ME, Athar M, Elmets CA and Afaq F: Fisetin inhibits
human melanoma cell invasion through promotion of mesenchymal to
epithelial transition and by targeting MAPK and NFκB signaling
pathways. PLoS One. 9:e863382014. View Article : Google Scholar : PubMed/NCBI
|
30
|
Ishikawa Y and Kitamura M: Dual potential
of extracellular signal-regulated kinase for the control of cell
survival. Biochem Biophys Res Commun. 264:696–701. 1999. View Article : Google Scholar : PubMed/NCBI
|
31
|
Ellinger-Ziegelbauer H, Brown K, Kelly K
and Siebenlist U: Direct activation of the stress-activated protein
kinase (SAPK) and extracellular signal-regulated protein kinase
(ERK) pathways by an inducible mitogen-activated protein Kinase/ERK
kinase kinase 3 (MEKK) derivative. J Biol Chem. 272:2668–2674.
1997. View Article : Google Scholar : PubMed/NCBI
|
32
|
Chou RH, Hsieh SC, Yu YL, Huang MH, Huang
YC and Hsieh YH: Fisetin inhibits migration and invasion of human
cervical cancer cells by down-regulating urokinase plasminogen
activator expression through suppressing the p38 MAPK-dependent
NF-κB signaling pathway. PLoS One. 8:e719832013. View Article : Google Scholar : PubMed/NCBI
|