Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis (Review)

  • Authors:
    • Özlem Erçen Diken
    • Aysun Şengül
    • Ayşe Coşkun Beyan
    • Ömer Ayten
    • Levent Cem Mutlu
    • Oğuzhan Okutan
  • View Affiliations

  • Published online on: November 29, 2018     https://doi.org/10.3892/etm.2018.7030
  • Pages: 587-595
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Abstract

Desquamative interstitial pneumonia is a type of smoking‑associated major idiopathic interstitial pneumonia, which is characterized by accumulation of alveolar macrophages in alveolar lumens and septa and develops secondary to mainly active or passive exposure to cigarette smoke. Desquamative interstitial pneumonia mostly occurs in male smokers in association with non‑specific symptoms responsive to steroid therapy and has a better prognosis than usual interstitial pneumonia. To date, no large‑scale clinical studies have been performed on desquamative interstitial pneumonia patients. Factors responsible for the scarcity of data on the clinical course of this condition include the retrospective nature of the available information as well as its rare occurrence. Despite this, a general consensus exists as to the nature of its symptoms, association with smoking, age and gender distribution, findings of respiratory function tests, steroid responsivity and mortality. The objective of the present review article was to report on desquamative interstitial pneumonia and to describe its etiology, risk factors and clinical features, as well as the laboratory, bronchoalveolar lavage, radiological and histopathological findings, and the treatment and prognosis of affected patients.
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January-2019
Volume 17 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Diken ÖE, Şengül A, Coşkun Beyan A , Ayten Ö, Mutlu LC and Okutan O: Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis (Review). Exp Ther Med 17: 587-595, 2019.
APA
Diken, Ö.E., Şengül, A., Coşkun Beyan, A. ., Ayten, Ö., Mutlu, L.C., & Okutan, O. (2019). Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis (Review). Experimental and Therapeutic Medicine, 17, 587-595. https://doi.org/10.3892/etm.2018.7030
MLA
Diken, Ö. E., Şengül, A., Coşkun Beyan, A. ., Ayten, Ö., Mutlu, L. C., Okutan, O."Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis (Review)". Experimental and Therapeutic Medicine 17.1 (2019): 587-595.
Chicago
Diken, Ö. E., Şengül, A., Coşkun Beyan, A. ., Ayten, Ö., Mutlu, L. C., Okutan, O."Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis (Review)". Experimental and Therapeutic Medicine 17, no. 1 (2019): 587-595. https://doi.org/10.3892/etm.2018.7030