Application value of thromboelastography in perioperative clinical blood transfusion and its effect on the outcome of patient

Shi,Haiyan; Shi,Bo; Lu,Jun; Wu,Lingling; Sun,Guang

doi:10.3892/etm.2019.7333

Application value of thromboelastography in perioperative clinical blood transfusion and its effect on the outcome of patient

Authors:
- Haiyan Shi
- Bo Shi
- Jun Lu
- Lingling Wu
- Guang Sun
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Affiliations: Department of Blood Transfusion, The First Hospital of Zibo, Zibo, Shandong 255000, P.R. China, Department of Neurology, The First Hospital of Zibo, Zibo, Shandong 255000, P.R. China, Department of Blood Transfusion, The Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, P.R. China, Department of Blood Transfusion, Quanzhou First Hospital Affiliated to Medical University of Fujian, Quanzhou, Fujian 362000, P.R. China, Department of Intensive Care Unit, Central Hospital of Zibo, Zibo, Shandong 255000, P.R. China
Published online on: March 1, 2019 https://doi.org/10.3892/etm.2019.7333
Pages: 3483-3488
Copyright: © Shi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Application value of thromboelastography (TEG) in perioperative clinical blood transfusion and its effect on the outcome of patient were investigated. Seventy-four patients, admitted to The Surgical Department of the First Hospital of Zibo from March 2015 to March 2018, were selected for this study. Among them, 34 patients took only the traditional coagulation function testing method as the blood transfusion guide during the perioperative period and they were regarded as the control group. The other 40 patients used TEG as the blood transfusion guide during the perioperative period, and they were regarded as the TEG group. The coagulation function indicators in 2 h before the operation and in 24 h after the operation, the transfusion amount and blood loss during the operation, the condition of the blood transfusion during the perioperative period, the occurrence rate of the postoperative rebleeding, the length of hospital stay and mortality of the patients in the two groups were compared. The coagulation function indicators of the patients in the two groups in 2 h before the operation and in 24 h after the operation showed that there was no significant difference between the two groups (P>0.050). However, APTT and Pt of the patients in the two groups both increased when compared with those before the treatment (P<0.050) and Hb, Hct, Plt and Fib all decreased (P<0.050). The suspended erythrocytes, Plt, fibrinogen and plasma in the TEG group were both significantly lower than those in the control group (P<0.001). Compared with the traditional coagulation function test, TEG was more accurate for estimating the coagulation function of patient and was more suitable for estimating the condition of blood transfusion of patient in the perioperative period; also, it could shorten the recovery period of patient and it is worthwhile to promote it in the clinic.

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