1
|
Egelberg J: Periodontics the Scientific
Way, Synopses of Clinical Studies1. 3rd. Odonto Science; Malmo: pp.
121999
|
2
|
Cugini MA, Haffajee AD, Smith C, Kent RL
Jr and Socransky SS: The effect of scaling and root planing on the
clinical and microbiological parameters of periodontal diseases:
12-month results. J Clin Periodontol. 27:30–36. 2000. View Article : Google Scholar : PubMed/NCBI
|
3
|
Carvalho LH, D'Avila GB, Leão A, Haffajee
AD, Socransky SS and Feres M: Scaling and root planing, systemic
metronidazole and professional plaque removal in the treatment of
chronic periodontitis in a Brazilian population. I. Clinical
results. J Clin Periodontol. 31:1070–1076. 2004. View Article : Google Scholar : PubMed/NCBI
|
4
|
Cosgarea R, Juncar R, Heumann C, Tristiu
R, Lascu L, Arweiler N, Stavropoulos A and Sculean A: Non-surgical
periodontal treatment in conjunction with 3 or 7 days systemic
administration of amoxicillin and metronidazole in severe chronic
periodontitis patients. A placebo-controlled randomized clinical
study. J Clin Periodontol. 43:767–777. 2016. View Article : Google Scholar : PubMed/NCBI
|
5
|
Renvert S, Wikström M, Dahlén G, Slots J
and Egelberg J: Effect of root debridement on the elimination of
Actinobacillus actinomycetemcomitans and Bacteroides
gingivalis from periodontal pockets. J Clin Periodontol.
17:345–350. 1990. View Article : Google Scholar : PubMed/NCBI
|
6
|
Mombelli A, Gmür R, Gobbi C and Lang NP:
Actinobacillus actinomycetemcomitans in adult periodontitis.
I. Topographic distribution before and after treatment. J
Periodontol. 65:820–826. 1994. View Article : Google Scholar : PubMed/NCBI
|
7
|
Marsh PD: Dental plaque: Biological
significance of a biofilm and community life-style. J Clin
Periodontol. 32 (Suppl 6):7–15. 2005. View Article : Google Scholar : PubMed/NCBI
|
8
|
van Winkelhoff AJ, Rodenburg JP, Goené RJ,
Abbas F, Winkel EG and de Graaff J: Metronidazole plus amoxycillin
in the treatment of Actinobacillus actinomycetemcomitans
associated periodontitis. J Clin Periodontol. 16:128–131. 1989.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Pavicić MJ, van Winkelhoff AJ, Douqué NH,
Steures RW and de Graaff J: Microbiological and clinical effects of
metronidazole and amoxicillin in Actinobacillus
actinomycetemcomitans-associated periodontitis. A 2-year
evaluation. J Clin Periodontol. 21:107–112. 1994. View Article : Google Scholar : PubMed/NCBI
|
10
|
Flemmig TF, Milián E, Karch H and Klaiber
B: Differential clinical treatment outcome after systemic
metronidazole and amoxicillin in patients harboring
Actinobacillus actinomycetemcomitans and/or Porphyromonas
gingivalis. J Clin Periodontol. 25:380–387. 1998. View Article : Google Scholar : PubMed/NCBI
|
11
|
Goutoudi P, Diza E and Arvanitidou M:
Effect of periodontal therapy on crevicular fluid interleukin-1beta
and interleukin-10 levels in chronic periodontitis. J Dent.
32:511–520. 2004. View Article : Google Scholar : PubMed/NCBI
|
12
|
Guerrero A, Griffiths GS, Nibali L, Suvan
J, Moles DR, Laurell L and Tonetti MS: Adjunctive benefits of
systemic amoxicillin and metronidazole in non-surgical treatment of
generalized aggressive periodontitis: A randomized
placebo-controlled clinical trial. J Clin Periodontol.
32:1096–1107. 2005. View Article : Google Scholar : PubMed/NCBI
|
13
|
Ehmke B, Moter A, Beikler T, Milian E and
Flemmig TF: Adjunctive antimicrobial therapy of periodontitis:
Long-term effects on disease progression and oral colonization. J
Periodontol. 76:749–759. 2005. View Article : Google Scholar : PubMed/NCBI
|
14
|
Cionca N, Giannopoulou C, Ugolotti G and
Mombelli A: Amoxicillin and metronidazole as an adjunct to
full-mouth scaling and root planing of chronic periodontitis. J
Periodontol. 80:364–371. 2009. View Article : Google Scholar : PubMed/NCBI
|
15
|
Cionca N, Giannopoulou C, Ugolotti G and
Mombelli A: Microbiologic testing and outcomes of full-mouth
scaling and root planing with or without amoxicillin/metronidazole
in chronic periodontitis. J Periodontol. 81:15–23. 2010. View Article : Google Scholar : PubMed/NCBI
|
16
|
Ribeiro EP, Bittencourt S, Zanin IC, Bovi
Ambrosano GM, Sallum EA, Nociti FH Jr, Gonçalves RB and Casati MZ:
Full-mouth ultrasonic debridement associated with amoxicillin and
metronidazole in the treatment of severe chronic periodontitis. J
Periodontol. 80:1254–1264. 2009. View Article : Google Scholar : PubMed/NCBI
|
17
|
Yek EC, Cintan S, Topcuoglu N, Kulekci G,
Issever H and Kantarci A: Efficacy of amoxicillin and metronidazole
combination for the management of generalized aggressive
periodontitis. J Periodontol. 81:964–974. 2010. View Article : Google Scholar : PubMed/NCBI
|
18
|
Rodrigues AS, Lourenção DS, Lima Neto LG,
Pannuti CM, Hirata RD, Hirata MH, Lotufo RF and De Micheli G:
Clinical and microbiologic evaluation, by real-time polymerase
chain reaction, of non-surgical treatment of aggressive
periodontitis associated with amoxicillin and metronidazole. J
Periodontol. 83:744–752. 2012. View Article : Google Scholar : PubMed/NCBI
|
19
|
Rooney J, Wade WG, Sprague SV, Newcombe RG
and Addy M: Adjunctive effects to non-surgical periodontal therapy
of systemic metronidazole and amoxycillin alone and combined. A
placebo controlled study. J Clin Periodontol. 29:342–350. 2002.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Matarazzo F, Figueiredo LC, Cruz SE,
Faveri M and Feres M: Clinical and microbiological benefits of
systemic metronidazole and amoxicillin in the treatment of smokers
with chronic periodontitis: A randomized placebo-controlled study.
J Clin Periodontol. 35:885–896. 2008. View Article : Google Scholar : PubMed/NCBI
|
21
|
Mestnik MJ, Feres M, Figueiredo LC, Duarte
PM, Lira EA and Faveri M: Short-term benefits of the adjunctive use
of metronidazole plus amoxicillin in the microbial profile and in
the clinical parameters of subjects with generalized aggressive
periodontitis. J Clin Periodontol. 37:353–365. 2010. View Article : Google Scholar : PubMed/NCBI
|
22
|
Mestnik MJ, Feres M, Figueiredo LC, Soares
G, Teles RP, Fermiano D, Duarte PM and Faveri M: The effects of
adjunctive metronidazole plus amoxicillin in the treatment of
generalized aggressive periodontitis: A 1-year double-blinded,
placebo-controlled, randomized clinical trial. J Clin Periodontol.
39:955–961. 2012. View Article : Google Scholar : PubMed/NCBI
|
23
|
Heller D, Varela VM, Silva-Senem MX,
Torres MC, Feres-Filho EJ and Colombo AP: Impact of systemic
antimicrobials combined with anti-infective mechanical debridement
on the microbiota of generalized aggressive periodontitis: A
6-month RCT. J Clin Periodontol. 38:355–364. 2011. View Article : Google Scholar : PubMed/NCBI
|
24
|
Silva MP, Feres M, Sirotto TA, Soares GM,
Mendes JA, Faveri M and Figueiredo LC: Clinical and microbiological
benefits of metronidazole alone or with amoxicillin as adjuncts in
the treatment of chronic periodontitis: A randomized
placebo-controlled clinical trial. J Clin Periodontol. 38:828–837.
2011. View Article : Google Scholar : PubMed/NCBI
|
25
|
Feres M, Soares GM, Mendes JA, Silva MP,
Faveri M, Teles R, Socransky SS and Figueiredo LC: Metronidazole
alone or with amoxicillin as adjuncts to non-surgical treatment of
chronic periodontitis: A 1-year double-blinded, placebo-controlled,
randomized clinical trial. J Clin Periodontol. 39:1149–1158. 2012.
View Article : Google Scholar : PubMed/NCBI
|
26
|
Griffiths GS, Ayob R, Guerrero A, Nibali
L, Suvan J, Moles DR and Tonetti MS: Amoxicillin and metronidazole
as an adjunctive treatment in generalized aggressive periodontitis
at initial therapy or re-treatment: A randomized controlled
clinical trial. J Clin Periodontol. 38:43–49. 2011. View Article : Google Scholar : PubMed/NCBI
|
27
|
Jorgensen MG and Slots J: Responsible use
of antimicrobials in periodontics. J Calif Dent Assoc. 28:185–193.
2000.PubMed/NCBI
|
28
|
Newman MG, Tkei HH, Klokkevold PR and
Carranza FA: Newman and Carranza's Clinical Periodontology.1. 13th.
Elsevier; Amsterdam: 2019
|
29
|
Vogelman B and Craig WA: Kinetics of
antimicrobial activity. J Pediatr. 108:835–840. 1986. View Article : Google Scholar : PubMed/NCBI
|
30
|
Cosgarea R, Heumann C, Juncar R, Tristiu
R, Lascu L, Salvi GE, Arweiler NB and Sculean A: One year results
of a randomized controlled clinical study evaluating the effects of
non-surgical periodontal therapy of chronic periodontitis in
conjunction with three or seven days systemic administration of
amoxicillin/metronidazole. PLoS One. 12:e01795922017. View Article : Google Scholar : PubMed/NCBI
|
31
|
Laxminarayan R, Duse A, Wattal C, Zaidi
AK, Wertheim HF, Sumpradit N, Vlieghe E, Hara GL, Gould IM,
Goossens H, et al: Antibiotic resistance-the need for global
solutions. Lancet Infect Dis. 13:1057–1098. 2013. View Article : Google Scholar : PubMed/NCBI
|
32
|
Mah MW and Memish ZA: Antibiotic
resistance. An impending crisis. Saudi Med J. 21:1125–1129.
2000.PubMed/NCBI
|
33
|
Rams TE, Degener JE and van Winkelhoff AJ:
Antibiotic resistance in human chronic periodontitis microbiota. J
Periodontol. 85:160–169. 2014. View Article : Google Scholar : PubMed/NCBI
|
34
|
van Winkelhoff AJ, Tijhof CJ and de Graaff
J: Microbiological and clinical results of metronidazole plus
amoxicillin therapy in Actinobacillus
actinomycetemcomitans-associated periodontitis. J Periodontol.
63:52–57. 1992. View Article : Google Scholar : PubMed/NCBI
|
35
|
van Winkelhoff AJ, Herrera D, Oteo A and
Sanz M: Antimicrobial profiles of periodontal pathogens isolated
from periodontitis patients in The Netherlands and Spain. J Clin
Periodontol. 32:893–898. 2005. View Article : Google Scholar : PubMed/NCBI
|
36
|
Feres M, Haffajee AD, Allard K, Som S,
Goodson JM and Socransky SS: Antibiotic resistance of subgingival
species during and after antibiotic therapy. J Clin Periodontol.
29:724–735. 2002. View Article : Google Scholar : PubMed/NCBI
|
37
|
Maestre JR, Bascones A, Sánchez P,
Matesanz P, Aguilar L, Giménez MJ, Pérez-Balcabao I, Granizo JJ and
Prieto J: Odontogenic bacteria in periodontal disease and
resistance patterns to common antibiotics used as treatment and
prophylaxis in odontology in Spain. Rev Esp Quimioter. 20:61–67.
2007.PubMed/NCBI
|
38
|
Lakhssassi N, Elhajoui N, Lodter JP,
Pineill JL and Sixou M: Antimicrobial susceptibility variation of
50 anaerobic periopathogens in aggressive periodontitis: An
interindividual variability study. Oral Microbiol Immunol.
20:244–252. 2005. View Article : Google Scholar : PubMed/NCBI
|
39
|
Dehelean CA, Soica C, Pinzaru I, Coricovac
D, Danciu C, Pavel I, Borcan F, Spandidos DA, Tsatsakis AM and
Baderca F: Sex differences and pathology status correlated to the
toxicity of some common carcinogens in experimental skin carcinoma.
Food Chem Toxicol. 95:149–158. 2016. View Article : Google Scholar : PubMed/NCBI
|
40
|
Pricop R, Cristea VC, Gheorghe I, Tatu AL,
Mihaescu G and Chifiriuc MC: Matrix-assisted laser
desorption/ionization time-of-flight mas spectrometry (MALDI-TOF
MS) reveals the anaerobic Slakia exigua as unique etiology
of a dental abscess. Biointerface Res Appl Chem. 7:1995–1997.
2017.
|
41
|
Oktay S, Chukkapalli SS, Rivera-Kweh MF,
Velsko IM, Holliday LS and Kesavalu L: Periodontitis in rats
induces systemic oxidative stress that is controlled by
bone-targeted antiresorptives. J Periodontol. 86:137–145. 2015.
View Article : Google Scholar : PubMed/NCBI
|
42
|
Căruntu C, Boda D, Musat S, Căruntu A and
Mandache E: Stress-induced mast cell activation in glabrous and
hairy skin. Mediators Inflamm. 2014:1059502014. View Article : Google Scholar : PubMed/NCBI
|
43
|
Dahiya P, Kamal R, Gupta R, Bhardwaj R,
Chaudhary K and Kaur S: Reactive oxygen species in periodontitis. J
Indian Soc Periodontol. 17:411–416. 2013. View Article : Google Scholar : PubMed/NCBI
|
44
|
Robinson JM: Reactive oxygen species in
phagocytic leukocytes. Histochem Cell Biol. 130:281–297. 2008.
View Article : Google Scholar : PubMed/NCBI
|
45
|
Tóthová L and Celec P: Oxidative stress
and antioxidants in the diagnosis and therapy of periodontitis.
Front Physiol. 8:10552017. View Article : Google Scholar : PubMed/NCBI
|
46
|
Tsai CC, Chen HS, Chen SL, Ho YP, Ho KY,
Wu YM and Hung CC: Lipid peroxidation: A possible role in the
induction and progression of chronic periodontitis. J Periodontal
Res. 40:378–384. 2005. View Article : Google Scholar : PubMed/NCBI
|
47
|
Konopka T, Król K, Kopeć W and Gerber H:
Total antioxidant status and 8-hydroxy-2-deoxyguanosine levels in
gingival and peripheral blood of periodontitis patients. Arch
Immunol Ther Exp (Warsz). 55:417–422. 2007. View Article : Google Scholar : PubMed/NCBI
|
48
|
Akalin FA, Baltacioğlu E, Alver A and
Karabulut E: Lipid peroxidation levels and total oxidant status in
serum, saliva and gingival crevicular fluid in patients with
chronic periodontitis. J Clin Periodontol. 34:558–565. 2007.
View Article : Google Scholar : PubMed/NCBI
|
49
|
Chapple IL, Brock GR, Milward MR, Ling N
and Matthews JB: Compromised GCF total antioxidant capacity in
periodontitis: Cause or effect? J Clin Periodontol. 34:103–110.
2007. View Article : Google Scholar : PubMed/NCBI
|
50
|
Armitage GC: Development of a
classification system for periodontal diseases and conditions. Ann
Periodontol. 4:1–6. 1999. View Article : Google Scholar : PubMed/NCBI
|
51
|
Tonetti MS, Pini-Prato G and Cortellini P:
Effect of cigarette smoking on periodontal healing following GTR in
infrabony defects. A preliminary retrospective study. J Clin
Periodontol. 22:229–234. 1995. View Article : Google Scholar : PubMed/NCBI
|
52
|
Miller PD Jr: A classification of marginal
tissue recession. Int J Periodontics Restorative Dent. 5:8–13.
1985.PubMed/NCBI
|
53
|
Hamp SE, Nyman S and Lindhe J: Periodontal
treatment of multirooted teeth. Results after 5 years. J Clin
Periodontol. 2:126–135. 1975. View Article : Google Scholar : PubMed/NCBI
|
54
|
Quirynen M, Bollen CML, Vandekerckhove BN,
Dekeyser C, Papaioannou W and Eyssen H: Full- vs. partial-mouth
disinfection in the treatment of periodontal infections: Short-term
clinical and microbiological observations. J Dent Res.
74:1459–1467. 1995. View Article : Google Scholar : PubMed/NCBI
|
55
|
Slots J: Selective medium for isolation of
Actinobacillus actinomycetemcomitans. J Clin Microbiol.
15:606–609. 1982.PubMed/NCBI
|
56
|
Tatu AL, Merezeanu N, Pântea O, Gheorghe
I, Popa M, Banu O, Cristea VC, Chifiriuc MC, Lazăr V and Marutescu
L: Resistance features of Pseudomonas aeruginosa strains
isolated from patients with infectious complications of
cardiovascular surgery. Biointerface Res Appl Chem. 7:2004–2008.
2017.
|
57
|
Gheorghe I, Tatu AL, Lupu I, Thamer O,
Cotar AI, Pircalabioru GG, Popa M, Cristea VC, Lazar V and
Chifiriuc MC: Molecular characterization of virulence and
resistance features in Staphylococcus aureus clinical strains
isolated from cutaneous lesions in patients with drug adverse
reactions. Rom Biotechnol Lett. 22:12321–12327. 2017.
|
58
|
R Core Team, . A language and Environment
for Statistical ComputingFoundation for Statistical Computing;
Vienna: pp. 2012017
|
59
|
Gamer M, Lemon J, Fellows I and Singh P:
irr: Various Coefficients of Interrater Reliability and Agreement.
R package version 0.84.1. 2019.
|
60
|
Hettmansperger TP and McKean JW: Robust
nonparametric statistical methods.1. 2nd. Chapman & Hall; Boca
Raton, FL: 2011
|
61
|
Kloke J and McKean J: Npsm R package
nonparametric statistical methods using RCRC Press; Boca Raton, FL:
pp. 2872019
|
62
|
Winkel EG, Van Winkelhoff AJ, Timmerman
MF, Van der Velden U and Van der Weijden GA: Amoxicillin plus
metronidazole in the treatment of adult periodontitis patients. A
double-blind placebo-controlled study. J Clin Periodontol.
28:296–305. 2001. View Article : Google Scholar : PubMed/NCBI
|
63
|
Heta S and Robo I: The side effects of the
most commonly used group of antibiotics in periodontal treatments.
Med Sci (Basel). 6:E62018.PubMed/NCBI
|
64
|
Rodrigues RM, Gonçalves C, Souto R,
Feres-Filho EJ, Uzeda M and Colombo AP: Antibiotic resistance
profile of the subgingival microbiota following systemic or local
tetracycline therapy. J Clin Periodontol. 31:420–427. 2004.
View Article : Google Scholar : PubMed/NCBI
|
65
|
Fiehn NE and Westergaard J:
Doxycycline-resistant bacteria in periodontally diseased
individuals after systemic doxycycline therapy and in healthy
individuals. Oral Microbiol Immunol. 5:219–222. 1990. View Article : Google Scholar : PubMed/NCBI
|
66
|
Feres M, Haffajee AD, Goncalves C, Allard
KA, Som S, Smith C, Goodson JM and Socransky SS: Systemic
doxycycline administration in the treatment of periodontal
infections (II). Effect on antibiotic resistance of subgingival
species. J Clin Periodontol. 26:784–792. 1999. View Article : Google Scholar : PubMed/NCBI
|
67
|
Walker CB: The acquisition of antibiotic
resistance in the periodontal microflora. Periodontol 2000.
10:79–88. 1996. View Article : Google Scholar : PubMed/NCBI
|
68
|
Herrera D, Roldán S, O'Connor A and Sanz
M: The periodontal abscess (II). Short-term clinical and
microbiological efficacy of 2 systemic antibiotic regimes. J Clin
Periodontol. 27:395–404. 2000. View Article : Google Scholar : PubMed/NCBI
|
69
|
Ardila CM, Granada MI and Guzmán IC:
Antibiotic resistance of subgingival species in chronic
periodontitis patients. J Periodontal Res. 45:557–563.
2010.PubMed/NCBI
|
70
|
Boda D, Negrei C, Nicolescu F and Balalau
C: Assessment of some oxidative stress parameters in methotrexate
treated psoriasis patients. Farmacia. 62:704–710. 2014.
|
71
|
Tamaki N, Tomofuji T, Ekuni D, Yamanaka R,
Yamamoto T and Morita M: Short-term effects of non-surgical
periodontal treatment on plasma level of reactive oxygen
metabolites in patients with chronic periodontitis. J Periodontol.
80:901–906. 2009. View Article : Google Scholar : PubMed/NCBI
|
72
|
Rahman K: Studies on free radicals,
antioxidants, and co-factors. Clin Interv Aging. 2:219–236.
2007.PubMed/NCBI
|
73
|
Nakayama K, Terawaki H, Nakayama M,
Iwabuchi M, Sato T and Ito S: Reduction of serum antioxidative
capacity during hemodialysis. Clin Exp Nephrol. 11:218–224. 2007.
View Article : Google Scholar : PubMed/NCBI
|
74
|
Kim JH, Baik HW, Yoon YS, Joung HJ, Park
JS, Park SJ, Jang EJ, Park SW, Kim SJ, Kim MJ, et al: Measurement
of antioxidant capacity using the biological antioxidant potential
test and its role as a predictive marker of metabolic syndrome.
Korean J Intern Med (Korean Assoc Intern Med). 29:31–39. 2014.
|
75
|
Tamaki N, Tomofuji T, Maruyama T, Ekuni D,
Yamanaka R, Takeuchi N and Yamamoto T: Relationship between
periodontal condition and plasma reactive oxygen metabolites in
patients in the maintenance phase of periodontal treatment. J
Periodontol. 79:2136–2142. 2008. View Article : Google Scholar : PubMed/NCBI
|
76
|
Machida T, Tomofuji T, Ekuni D, Yamane M,
Yoneda T, Kawabata Y, Kataoka K, Tamaki N and Morita M:
Longitudinal relationship between plasma reactive oxygen
metabolites and periodontal condition in the maintenance phase of
periodontal treatment. Dis Markers. 2014:4892922014. View Article : Google Scholar : PubMed/NCBI
|
77
|
D'Aiuto F, Nibali L, Parkar M, Patel K,
Suvan J and Donos N: Oxidative stress, systemic inflammation, and
severe periodontitis. J Dent Res. 89:1241–1246. 2010. View Article : Google Scholar : PubMed/NCBI
|
78
|
Boda D: Cellomics as integrative omics for
cancer. Curr Proteomics. 10:237–245. 2013. View Article : Google Scholar
|
79
|
Gupta A, Govila V and Saini A: Proteomics
- The research frontier in periodontics. J Oral Biol Craniofac Res.
5:46–52. 2015. View Article : Google Scholar : PubMed/NCBI
|
80
|
Calenic B, Greabu M, Caruntu C, Nicolescu
MI, Moraru L, Surdu-Bob CC, Badulescu M, Anghel A, Logofatu C and
Boda D: Oral keratinocyte stem cells behavior on diamond like
carbon films. Rom Biotechnol Lett. 21:11914–11922. 2016.
|