Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature

Gao,Xiaoming; Cheng,Qian; Zhang,Xiaofei; Zhao,Guoyang

doi:10.3892/etm.2020.8503

Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature

Authors:
- Xiaoming Gao
- Qian Cheng
- Xiaofei Zhang
- Guoyang Zhao
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Affiliations: Department of Orthopedics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212000, P.R. China, Department of Orthopedics, Tong Ren Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200336, P.R. China, Department of Gynecology and Obstetrics, Shanghai First Maternal and Infant Healthcare Hospital Affiliated to Shanghai Tongji University, Shanghai 200040, P.R. China
Published online on: February 10, 2020 https://doi.org/10.3892/etm.2020.8503
Pages: 2702-2706
Copyright: © Gao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Osteopetrosis is a rare congenital bone disorder, characterized by systemic osteosclerosis due to a deficiency of or functional defect in osteoclasts. Autosomal dominant osteopetrosis (ADOP) is the most common form with a late onset, a stable condition, relatively few symptoms and a good prognosis. Few studies to date have reported successful total hip arthroplasty (THA) in patients with ADOP and its operative difficulties. We herein describe a case of left hip osteoarthritis in a patient with OP via THA in order to share our experience during the treatment process. The patient was a 52‑years‑old female with osteopetrosis who was referred to our department due to a history of left hip pain with activity limitation for 20 years. The patient reported no history of fracture or family history. The patient underwent THA in the left hip. At the 6‑month, 1‑ and 2‑year follow‑up, the components were in a good position and the patient remained asymptomatic and pain‑free. Therefore, THA may be a feasible treatment option when patients with ADOP suffer from painful hip osteoarthritis.

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