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Characteristics of patients at initiation of renal replacement therapy ‑ experience of a hemodialysis center

  • Authors:
    • Delia Timofte
    • Dorin Dragos
    • Andra‑Elena Balcangiu‑Stroescu
    • Maria‑Daniela Tanasescu
    • Daniela Gabriela Balan
    • Laura Raducu
    • Cristian‑Radu Jecan
    • Ovidiu Stiru
    • Lavinia Medrihan
    • Dorin Ionescu

  • View Affiliations

  • Published online on: March 17, 2020     https://doi.org/10.3892/etm.2020.8608
  • Pages: 103-108

  • Copyright: © Timofte et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The monitoring and care of patients with chronic kidney disease (CKD) before the dialysis initiation contribute to a better survival rate and an improvement in quality of life. The patients who do not benefit from a good predialysis management have a worse short and long‑term prognosis. A retrospective, unicentric study was performed to evaluate the status of patients with stage 5 CKD at the time of initiation of renal replacement treatment. A total of 109 patients were included in the study. The evaluation of the patients included the clinical manifestations leading to hemodialysis initiation, the clinical and laboratory data of the patients when the hemodialysis was started. Based on the obtained data, a statistical analysis was performed using the Chi‑square test, Fisher's exact test, ANOVA, and Kruskal‑Wallis H test. The mean age of the patients was 64.61±13.59 years. Of the patients 51.38% were women. Vascular nephropathies and diabetes mellitus dominated the etiology of CKD. The comorbidities were high blood pressure, ischemic heart disease, history of myocardial infarction, heart failure, history of stroke, peripheral artery disease or atrial fibrillation. Only 43 (39.45%) of our patients were monitored before the hemodialysis initiation. Hemodialysis was initiated on central venous catheter (in most cases non-tunneled) in 78.90% of the patients. Most of the patients had an altered general status, fatigue/tiredness with poor exercise capacity when hemodialysis was initiated. Most of the patients (98.17%) had anemia, the average level of hemoglobin being 8.69±1.85 g/dl. In conclusion, careful monitoring of patients in the early stages of CKD would result in lower morbidity and mortality. These objectives can be achieved by implementing screening programs and early interventions.
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July-2020
Volume 20 Issue 1

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Spandidos Publications style
Timofte D, Dragos D, Balcangiu‑Stroescu AE, Tanasescu MD, Balan DG, Raducu L, Jecan CR, Stiru O, Medrihan L, Ionescu D, Ionescu D, et al: Characteristics of patients at initiation of renal replacement therapy ‑ experience of a hemodialysis center. Exp Ther Med 20: 103-108, 2020.
APA
Timofte, D., Dragos, D., Balcangiu‑Stroescu, A., Tanasescu, M., Balan, D.G., Raducu, L. ... Ionescu, D. (2020). Characteristics of patients at initiation of renal replacement therapy ‑ experience of a hemodialysis center. Experimental and Therapeutic Medicine, 20, 103-108. https://doi.org/10.3892/etm.2020.8608
MLA
Timofte, D., Dragos, D., Balcangiu‑Stroescu, A., Tanasescu, M., Balan, D. G., Raducu, L., Jecan, C., Stiru, O., Medrihan, L., Ionescu, D."Characteristics of patients at initiation of renal replacement therapy ‑ experience of a hemodialysis center". Experimental and Therapeutic Medicine 20.1 (2020): 103-108.
Chicago
Timofte, D., Dragos, D., Balcangiu‑Stroescu, A., Tanasescu, M., Balan, D. G., Raducu, L., Jecan, C., Stiru, O., Medrihan, L., Ionescu, D."Characteristics of patients at initiation of renal replacement therapy ‑ experience of a hemodialysis center". Experimental and Therapeutic Medicine 20, no. 1 (2020): 103-108. https://doi.org/10.3892/etm.2020.8608