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Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females

  • Authors:
    • Vasileios Souftas
    • Dorelia Deuteraiou
    • Xanthoula Anthoulaki
    • Anna Chalkidou
    • Anastasia Bothou
    • Fotini Gaidatzi
    • Grigorios Tsypsianis
    • Georgios Iatrakis
    • Stefanos Zervoudis
    • Dimitrios Souftas
    • Spyridon Michalopoulos
    • Theodosia Vogiatzaki
    • George Galazios
    • Nikolaos Nikolettos
    • Panagiotis Tsikouras
  • View Affiliations / Copyright

    Affiliations: Department of Interventional Radiology and Medical Imaging, Medical Faculty, Democritus University of Thrace, Alexandroupolis 68100, Greece, Department of Obstetrics and Gynecology, Medical Faculty, Democritus University of Thrace, Alexandroupolis 68100, Greece, Department of Obstetrics and Mastology, Rea Hospital, Athens 17564, Greece, Department of Medical Statistics, Medical Faculty, Democritus University of Thrace, Alexandroupolis 68100, Greece, University of West Attica, Department of Midwifery, Athens 17564, Greece, Department of Social Administration, Democritus University of Thrace, Alexandroupolis 68100, Greece, Department of Anesthesiology and Pain Treatment, Democritus University of Thrace, Alexandroupolis 68100, Greece
    Copyright: © Souftas et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3684-3690
    |
    Published online on: April 9, 2020
       https://doi.org/10.3892/etm.2020.8652
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Abstract

The purpose of the present study was to describe the course of changes in laboratory inflammatory markers following bilateral uterine artery embolization (UAE) as a treatment for leiomyomas and adenomyosis. The body temperature was measured and blood samples were collected to determine white blood cell (WBC) count and C‑reactive protein (CRP) levels in 270 patients on the day prior to UAE and for up to 4 days post‑embolization. Aside from a single case with a non‑inflammatory complication, none of the other cases had any complications. Post‑UAE leukocytosis with a mean maximum value of 10.8±3.5x109/l (range, 5.9‑18.6x109/l) was observed one‑year post‑intervention. The mean leukocyte numbers were indicated to be higher on day 3 post‑UAE. The CRP level was also increased post‑UAE, with a mean maximum value of 7.75±3.5 mg/dl. Maximum levels were reached in 8 patients on the 2nd and in 11 patients on the 3rd post‑operative day. The maximum pain score was ~5.5 and reached its lowest level at the end of the 12th week post‑intervention. The present study did not consider an association between the embolic material used or uterus size with the level of treatment success. No complications were observed post‑UAE; however, a significant increase in the WBC count was observed within the first 3 days, indicating mild leukocytosis.
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Copy and paste a formatted citation
Spandidos Publications style
Souftas V, Deuteraiou D, Anthoulaki X, Chalkidou A, Bothou A, Gaidatzi F, Tsypsianis G, Iatrakis G, Zervoudis S, Souftas D, Souftas D, et al: Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females. Exp Ther Med 19: 3684-3690, 2020.
APA
Souftas, V., Deuteraiou, D., Anthoulaki, X., Chalkidou, A., Bothou, A., Gaidatzi, F. ... Tsikouras, P. (2020). Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females. Experimental and Therapeutic Medicine, 19, 3684-3690. https://doi.org/10.3892/etm.2020.8652
MLA
Souftas, V., Deuteraiou, D., Anthoulaki, X., Chalkidou, A., Bothou, A., Gaidatzi, F., Tsypsianis, G., Iatrakis, G., Zervoudis, S., Souftas, D., Michalopoulos, S., Vogiatzaki, T., Galazios, G., Nikolettos, N., Tsikouras, P."Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females". Experimental and Therapeutic Medicine 19.6 (2020): 3684-3690.
Chicago
Souftas, V., Deuteraiou, D., Anthoulaki, X., Chalkidou, A., Bothou, A., Gaidatzi, F., Tsypsianis, G., Iatrakis, G., Zervoudis, S., Souftas, D., Michalopoulos, S., Vogiatzaki, T., Galazios, G., Nikolettos, N., Tsikouras, P."Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females". Experimental and Therapeutic Medicine 19, no. 6 (2020): 3684-3690. https://doi.org/10.3892/etm.2020.8652
Copy and paste a formatted citation
x
Spandidos Publications style
Souftas V, Deuteraiou D, Anthoulaki X, Chalkidou A, Bothou A, Gaidatzi F, Tsypsianis G, Iatrakis G, Zervoudis S, Souftas D, Souftas D, et al: Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females. Exp Ther Med 19: 3684-3690, 2020.
APA
Souftas, V., Deuteraiou, D., Anthoulaki, X., Chalkidou, A., Bothou, A., Gaidatzi, F. ... Tsikouras, P. (2020). Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females. Experimental and Therapeutic Medicine, 19, 3684-3690. https://doi.org/10.3892/etm.2020.8652
MLA
Souftas, V., Deuteraiou, D., Anthoulaki, X., Chalkidou, A., Bothou, A., Gaidatzi, F., Tsypsianis, G., Iatrakis, G., Zervoudis, S., Souftas, D., Michalopoulos, S., Vogiatzaki, T., Galazios, G., Nikolettos, N., Tsikouras, P."Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females". Experimental and Therapeutic Medicine 19.6 (2020): 3684-3690.
Chicago
Souftas, V., Deuteraiou, D., Anthoulaki, X., Chalkidou, A., Bothou, A., Gaidatzi, F., Tsypsianis, G., Iatrakis, G., Zervoudis, S., Souftas, D., Michalopoulos, S., Vogiatzaki, T., Galazios, G., Nikolettos, N., Tsikouras, P."Significance of changes in inflammatory parameters following uterine artery embolization in pre‑menopausal females". Experimental and Therapeutic Medicine 19, no. 6 (2020): 3684-3690. https://doi.org/10.3892/etm.2020.8652
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