Animal models of vertical bone augmentation (Review)
- Authors:
- Zepeng Zhang
- Yaxin Gan
- Yarong Guo
- Xuguang Lu
- Xianqi Li
-
Affiliations: Department of Oral and Maxillofacial Surgery, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi 030001, P.R. China - Published online on: June 30, 2021 https://doi.org/10.3892/etm.2021.10351
- Article Number: 919
-
Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
|
Yim HJ, Lim HC, Hong JY, Shin SI, Chung JH, Herr Y and Shin SY: Primary stability of implants with peri-implant bone defects of various widths: An in vitro investigation. J Periodontal Implant Sci. 49:39–46. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Moy PK, Medina D, Shetty V and Aghaloo TL: Dental implant failure rates and associated risk factors. Int J Oral Maxillofac Implants. 20:569–577. 2005.PubMed/NCBI | |
|
Urban IA, Montero E, Monje A and Sanz-Sánchez I: Effectiveness of vertical ridge augmentation interventions: A systematic review and meta-analysis. J Clin Periodontol. 46 (Suppl 21):S319–S339. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Elnayef B, Monje A, Gargallo-Albiol J, Galindo-Moreno P, Wang HL and Hernández-Alfaro F: Vertical ridge augmentation in the atrophic mandible: A Systematic review and meta-analysis. Int J Oral Maxillofac Implants. 32:291–312. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Wang HL and Boyapati L: ‘PASS’ principles for predictable bone regeneration. Implant Dent. 15:8–17. 2006.PubMed/NCBI View Article : Google Scholar | |
|
Artzi Z, Nemcovsky CE, Tal H, Weinberg E, Weinreb M, Prasad H, Rohrer MD and Kozlovsky A: Simultaneous versus two-stage implant placement and guided bone regeneration in the canine: Histomorphometry at 8 and 16 months. J Clin Periodontol. 37:1029–1038. 2010.PubMed/NCBI View Article : Google Scholar | |
|
Kon K, Shiota M, Ozeki M and Kasugai S: The effect of graft bone particle size on bone augmentation in a rabbit cranial vertical augmentation model: A microcomputed tomography study. Int J Oral Maxillofac Implants. 29:402–406. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Kim JW, Jeong IH, Lee KI, Jung UW, Kim CS, Choi SH, Cho KS and Yun JH: Volumetric bone regenerative efficacy of biphasic calcium phosphate-collagen composite block loaded with rhBMP-2 in vertical bone augmentation model of a rabbit calvarium. J Biomed Mater Res A. 100:3304–3313. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Nkenke E and Neukam FW: Autogenous bone harvesting and grafting in advanced jaw resorption: Morbidity, resorption and implant survival. Eur J Oral Implantol. 7 (Suppl 2):S203–S217. 2014.PubMed/NCBI | |
|
Zigdon-Giladi H, Bick T, Morgan EF, Lewinson D and Machtei EE: Peripheral blood-derived endothelial progenitor cells enhance vertical bone formation. Clin Implant Dent Relat Res. 17:83–92. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Rachmiel A, Shilo D, Aizenbud D and Emodi O: Vertical alveolar distraction osteogenesis of the atrophic posterior mandible before dental implant insertion. J Oral Maxillofac Surg. 75:1164–1175. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Tamimi F, Torres J, Gbureck U, Lopez-Cabarcos E, Bassett DC, Alkhraisat MH and Barralet JE: Craniofacial vertical bone augmentation: A comparison between 3D printed monolithic monetite blocks and autologous onlay grafts in the rabbit. Biomaterials. 30:6318–6326. 2009.PubMed/NCBI View Article : Google Scholar | |
|
Giesenhagen B, Martin N, Donkiewicz P, Perić Kačarević Ž, Smeets R, Jung O, Schnettler R and Barbeck M: Vertical bone augmentation in a single-tooth gap with an allogenic bone ring: Clinical considerations. J Esthet Restor Dent. 30:480–483. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Giesenhagen B, Martin N, Jung O and Barbeck M: Bone augmentation and simultaneous implant placement with allogenic bone rings and analysis of its purification success. Materials (Basel). 12(1291)2019.PubMed/NCBI View Article : Google Scholar | |
|
Stevens MR, Emam HA, Alaily ME and Sharawy M: Implant bone rings. One-stage three-dimensional bone transplant technique: A case report. J Oral Implantol. 36:69–74. 2010.PubMed/NCBI View Article : Google Scholar | |
|
Nakahara K, Haga-Tsujimura M, Sawada K, Kobayashi E, Mottini M, Schaller B and Saulacic N: Single-staged vs. two-staged implant placement using bone ring technique in vertically deficient alveolar ridges-Part 1: Histomorphometric and micro-CT analysis. Clin Oral Implants Res. 27:1384–1391. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Nakahara K, Haga-Tsujimura M, Sawada K, Kobayashi E, Schaller B and Saulacic N: Single-staged vs. two-staged implant placement in vertically deficient alveolar ridges using bone ring technique-Part 2: Implant osseointegration. Clin Oral Implants Res. 28:e31–e38. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Sakkas A, Wilde F, Heufelder M, Winter K and Schramm A: Autogenous bone grafts in oral implantology-is it still a ‘gold standard’? A consecutive review of 279 patients with 456 clinical procedures. Int J Implant Dent. 3(23)2017.PubMed/NCBI View Article : Google Scholar | |
|
Yang Y, Cheng Y, Peng S, Xu L, He C, Qi F, Zhao M and Shuai C: Microstructure evolution and texture tailoring of reduced graphene oxide reinforced Zn scaffold. Bioact Mater. 6:1230–1241. 2021.PubMed/NCBI View Article : Google Scholar | |
|
Zeeshan S, Corneliu S and Michael G: Bone replacement materials and techniques used for achieving vertical alveolar bone augmentation. Materials. 8:2953–2993. 2015. | |
|
Donos N, Dereka X and Mardas N: Experimental models for guided bone regeneration in healthy and medically compromised conditions. Periodontol. 68:99–121. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Li Y, Chen SK, Li L, Qin L, Wang XL and Lai YX: Bone defect animal models for testing efficacy of bone substitute biomaterials. J Orthop Translat. 3:95–104. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Newman E, Turner AS and Wark JD: The potential of sheep for the study of osteopenia: Current status and comparison with other animal models. Bone. 16 (Suppl 4):277S–284S. 1995.PubMed/NCBI View Article : Google Scholar | |
|
Gomes PS and Fernandes MH: Rodent models in bone-related research: The relevance of calvarial defects in the assessment of bone regeneration strategies. Lab Anim. 45:14–24. 2011.PubMed/NCBI View Article : Google Scholar | |
|
Schlegel KA, Lang FJ, Donath K, Kulow JT and Wiltfang J: The monocortical critical size bone defect as an alternative experimental model in testing bone substitute materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 102:7–13. 2006.PubMed/NCBI View Article : Google Scholar | |
|
Aerssens J, Boonen S, Lowet G and Dequeker J: Interspecies differences in bone composition, density, and quality: Potential implications for in vivo bone research. Endocrinology. 139:663–670. 1998.PubMed/NCBI View Article : Google Scholar | |
|
Hoornaert A, Maazouz Y, Pastorino D, Aparicio C, de Pinieux G, Fellah BH, Ginebra MP and Layrolle P: Vertical bone regeneration with synthetic biomimetic calcium phosphate onto the calvaria of rats. Tissue Eng Part C Methods. 25:1–11. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Zhang P, Ding L and Kasugai S: Effect of doxycycline doped bone substitute on vertical bone augmentation on rat calvaria. Dent Mater J. 38:211–217. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Shino H, Hasuike A, Arai Y, Honda M, Isokawa K and Sato S: Melatonin enhances vertical bone augmentation in rat calvaria secluded spaces. Med Oral Patol Oral Cir Bucal. 21:e122–e126. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Zigdon H, Lewinson D, Bick T and Machtei EE: Vertical bone augmentation using different osteoconductive scaffolds combined with barrier domes in the rat calvarium. Clin Implant Dent Relat Res. 16:138–144. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Zigdon-Giladi H, Lewinson D, Bick T and Machtei EE: Mesenchymal stem cells combined with barrier domes enhance vertical bone formation. J Clin Periodontol. 40:196–202. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Hao J, Chou J, Kuroda S, Otsuka M, Kasugai S and Lang NP: Strontium hydroxyapatite in situ gel-forming system-a new approach for minimally invasive bone augmentation. Clin Oral Implants Res. 26:581–585. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Hao J, Chou J, Kuroda S, Otsuka M, Kasugai S and Lang NP: Injectable simvastatin gel for minimally invasive periosteal distraction: In vitro and in vivo studies in rat. Clin Oral Implants Res. 29:227–234. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Berendsen AD and Olsen BR: Bone development. Bone. 80:14–18. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Marger L, Barone A, Martinelli-Kläy CP, Schaub L, Strasding M, Mekki M, Sailer I, Scherrer SS and Durual S: Calvarial model of bone augmentation in rabbit for assessment of bone growth and neovascularization in bone substitution materials. J Vis Exp: Aug 13, 2019 doi: 10.3791/59976. | |
|
Verna C, Dalstra M, Wikesjö UM and Trombelli L: Healing patterns in calvarial bone defects following guided bone regeneration in rats. A micro-CT scan analysis. J Clin Periodontol. 29:865–870. 2002.PubMed/NCBI View Article : Google Scholar | |
|
Lundgren D, Lundgren AK, Sennerby L and Nyman S: Augmentation of intramembraneous bone beyond the skeletal envelope using an occlusive titanium barrier. An experimental study in the rabbit. Clin Oral Implants Res. 6:67–72. 1995.PubMed/NCBI View Article : Google Scholar | |
|
Bigham-Sadegh A and Oryan A: Selection of animal models for pre-clinical strategies in evaluating the fracture healing, bone graft substitutes and bone tissue regeneration and engineering. Connect Tissue Res. 56:175–194. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Zakaria O, Madi M and Kasugai S: A novel osteogenesis technique: The expansible guided bone regeneration. J Tissue Eng. 3(2041731412441194)2012.PubMed/NCBI View Article : Google Scholar | |
|
Kim JM, Kim JH, Lee BH and Choi SH: Vertical bone augmentation using three-dimensionally printed cap in the rat calvarial partial defect. In Vivo. 32:1111–1117. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Lee SH, Lim P and Yoon HJ: The influence of cortical perforation on guided bone regeneration using synthetic bone substitutes: A study of rabbit cranial defects. Int J Oral Maxillofac Implants. 29:464–471. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Majzoub Z, Berengo M, Giardino R, Aldini NN and Cordioli G: Role of intramarrow penetration in osseous repair: A pilot study in the rabbit calvaria. J Periodontol. 70:1501–1510. 1999.PubMed/NCBI View Article : Google Scholar | |
|
Kinard LA, Dahlin RL, Henslee AM, Spicer PP, Chu CY, Tabata Y, van den Beucken JJ, Jansen JA, Young S, Wong ME, et al: Tissue response to composite hydrogels for vertical bone augmentation in the rat. J Biomed Mater Res A. 102:2079–2088. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Gilsanz V, Roe TF, Gibbens DT, Schulz EE, Carlson ME, Gonzalez O and Boechat MI: Effect of sex steroids on peak bone density of growing rabbits. Am J Physiol. 255:e416–e421. 1988.PubMed/NCBI View Article : Google Scholar | |
|
Castañeda S, Largo R, Calvo E, Rodríguez-Salvanés F, Marcos ME, Díaz-Curiel M and Herrero-Beaumont G: Bone mineral measurements of subchondral and trabecular bone in healthy and osteoporotic rabbits. Skeletal Radiol. 35:34–41. 2006.PubMed/NCBI View Article : Google Scholar | |
|
Campillo VE, Langonnet S, Pierrefeu A and Chaux-Bodard AG: Anatomic and histological study of the rabbit mandible as an experimental model for wound healing and surgical therapies. Lab Anim. 48:273–277. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Namli H, Erdogan Ö, Gönlüşen G, Kahraman OE, Aydin HM, Karabag S and Tatli U: Vertical bone augmentation using bone marrow-derived stem cells: An in vivo study in the rabbit calvaria. Implant Dent. 25:54–62. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Polo CI, Sendyk WR, Correa L, Sendyk D, Deboni MCZ and Naclério-Homem MDG: Synergism between recombinant human bone morphogenetic protein 2/absorbable collagen sponge and bone substitutes favors vertical bone augmentation and the resorption rate of the biomaterials: Histomorphometric and 3D microcomputed tomography analysis. J Periodontol. 91:1295–1306. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Sudheesh Kumar PT, Hashimi S, Saifzadeh S, Ivanovski S and Vaquette C: Additively manufactured biphasic construct loaded with BMP-2 for vertical bone regeneration: A pilot study in rabbit. Mater Sci Eng C Mater Biol Appl. 92:554–564. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Lee JS, Lee JS, Kang MH, Jung UW, Choi SH and Cho KS: Proof-of-concept study of vertical augmentation using block-type allogenic bone grafts: A preclinical experimental study on rabbit calvaria. J Biomed Mater Res B Appl Biomater. 106:2700–2707. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Sheikh Z, Drager J, Zhang YL, Abdallah MN, Tamimi F and Barralet J: Controlling bone graft substitute microstructure to improve bone augmentation. Adv Healthc Mater. 5:1646–1655. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Sheikh Z, Chen G, Thévenin M, Young RN, Grynpas MD and Glogauer M: A novel anabolic conjugate (C3) in the matrix of dicalcium phosphate onlay block grafts for achieving vertical bone augmentation: An experimental study on rabbit calvaria. Int J Oral Maxillofac Implants. 34:e51–e63. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Tamimi F, Torres J, Al-Abedalla K, Lopez-Cabarcos E, Alkhraisat MH, Bassett DC, Gbureck U and Barralet JE: Osseointegration of dental implants in 3D-printed synthetic onlay grafts customized according to bone metabolic activity in recipient site. Biomaterials. 35:5436–5445. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Draenert FG, Kammerer PW, Palarie V and Wagner W: Vertical bone augmentation with simultaneous dental implantation using crestal biomaterial rings: A rabbit animal study. Clin Implant Dent Relat Res. 14 (Suppl 1):e169–e174. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Kim YJ, de Molon RS, Horiguti FR, Contador GP, Coelho MA, Mascarenhas VI, de Souza Faloni AP, Cirelli JA and Sendyk WR: Vertical bone augmentation using deproteinized bovine bone mineral, absorbable collagen sponge, and recombinant human bone morphogenetic protein-2: An in vivo study in rabbits. Int J Oral Maxillofac Implants. 33:512–522. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Veis A, Dabarakis N, Koutrogiannis C, Barlas I, Petsa E and Romanos G: Evaluation of vertical bone regeneration using block and particulate forms of Bio-oss bone graft: A histologic study in the rabbit mandible. J Oral Implantol. 41:e66–e72. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Pripatnanont P, Balabid F, Pongpanich S and Vongvatcharanon S: Effect of osteogenic periosteal distraction by a modified Hyrax device with and without platelet-rich fibrin on bone formation in a rabbit model: A pilot study. Int J Oral Maxillofac Surg. 44:656–663. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Thoma DS, Kruse A, Ghayor C, Jung RE and Weber FE: Bone augmentation using a synthetic hydroxyapatite/silica oxide-based and a xenogenic hydroxyapatite-based bone substitute materials with and without recombinant human bone morphogenetic protein-2. Clin Oral Implants Res. 26:592–598. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Lai CH, Zhou L, Wang ZL, Lu HB and Gao Y: Use of a collagen membrane loaded with recombinant human bone morphogenetic protein-2 with collagen-binding domain for vertical guided bone regeneration. J Periodontol. 84:950–957. 2013.PubMed/NCBI View Article : Google Scholar | |
|
de Molon RS, Sakakura CE, Faeda RS, Sartori R, Palhares D, Margonar R and Marcantonio E Jr: Effect of the long-term administration of Cyclosporine A on bone healing around osseointegrated titanium implants: A histomorphometric study in the rabbit tibia. Microsc Res Tech. 80:1000–1008. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Cohen DJ, Cheng A, Kahn A, Aviram M, Whitehead AJ, Hyzy SL, Clohessy RM, Boyan BD and Schwartz Z: Novel osteogenic Ti-6Al-4V device for restoration of dental function in patients with large bone deficiencies: Design, development and implementation. Sci Rep. 6(20493)2016.PubMed/NCBI View Article : Google Scholar | |
|
Wancket LM: Animal models for evaluation of bone implants and devices: Comparative bone structure and common model uses. Vet Pathol. 52:842–850. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Reitan K and Kvam E: Comparative behavior of human and animal tissue during experimental tooth movement. Angle Orthod. 41:1–14. 1971.PubMed/NCBI View Article : Google Scholar | |
|
Kimmel DB and Jee WS: A quantitative histologic study of bone turnover in young adult beagles. Anat Rec. 203:31–45. 1982.PubMed/NCBI View Article : Google Scholar | |
|
Carrel JP, Wiskott A, Scherrer S and Durual S: Large bone vertical augmentation using a three-dimensional printed TCP/HA bone graft: A pilot study in dog mandible. Clin Implant Dent Relat Res. 18:1183–1192. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Teng F, Wei L, Yu D, Deng L, Zheng Y, Lin H and Liu Y: Vertical bone augmentation with simultaneous implantation using deproteinized bovine bone block functionalized with a slow delivery of BMP-2. Clin Oral Implants Res. 31:215–228. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Schwarz F, Mihatovic I, Popal-Jensen I, Parvini P and Sader R: Influence of autoclavation on the efficacy of extracted tooth roots used for vertical alveolar ridge augmentation. J Clin Periodontol. 46:502–509. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Parvini P, Schwarz F, Hüfner MK, Rauch N, Nienkemper M and Becker K: Microstructural volumetric analysis of vertical alveolar ridge augmentation using autogenous tooth roots. Clin Implant Dent Relat Res. 22:647–653. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Parvini P, Schliephake C, Al-Maawi S, Schwarz K, Sader R, Ghanaati S and Schwarz F: Histomorphometrical assessment of vertical alveolar ridge augmentation using extracted tooth roots in the canine. Clin Oral Investig. 24:317–323. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Hsu YT, Al-Hezaimi K, Galindo-Moreno P, O'Valle F, Al-Rasheed A and Wang HL: Effects of recombinant human bone morphogenetic protein-2 on vertical bone augmentation in a canine model. J Periodontol. 88:896–905. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Xuan F, Lee CU, Son JS, Fang Y, Jeong SM and Choi BH: Vertical ridge augmentation using xenogenous bone blocks: A comparison between the flap and tunneling procedures. J Oral Maxillofac Surg. 72:1660–1670. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Esposito M, Trullenque-Eriksson A, Vila CN, Peñarrocha M, García A, Sánchez A, Muñoz-Guzón F and Martínez Martín JM: Vertical osseodistraction with a new intraosseous alveolar distractor prototype for dental implant rehabilitation: A pilot study in dogs. Int J Oral Maxillofac Implants. 32:838–848. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Terbish M, Yoo SH, Kim HJ, Yu HS, Hwang CJ, Baik HS and Cha JY: Accelerated bone formation in distracted alveolar bone after injection of recombinant human bone morphogenetic protein-2. J Periodontol. 86:1078–1086. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Kaner D, Zhao H, Terheyden H and Friedmann A: Improvement of microcirculation and wound healing in vertical ridge augmentation after pre-treatment with self-inflating soft tissue expanders-a randomized study in dogs. Clin Oral Implants Res. 26:720–724. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Kaner D, Zhao H, Arnold W, Terheyden H and Friedmann A: Pre-augmentation soft tissue expansion improves scaffold-based vertical bone regeneration-a randomized study in dogs. Clin Oral Implants Res. 28:640–647. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Sawada K, Nakahara K, Haga-Tsujimura M, Iizuka T, Fujioka-Kobayashi M, Igarashi K and Saulacic N: Comparison of three block bone substitutes for bone regeneration: Long-term observation in the beagle dog. Odontology. 106:398–407. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Bianchini MA, Pontual MA, Bez L, Benfatti CA, Boabaid F, Somerman MJ and Magini RS: The use of bovine screws to promote bone formation using a tibia model in dogs. Oral Surg Oral Med Oral Pathol Oral Radiol. 116:e215–e220. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Pearce AI, Richards RG, Milz S, Schneider E and Pearce SG: Animal models for implant biomaterial research in bone: A review. Eur Cell Mater. 13:1–10. 2007.PubMed/NCBI View Article : Google Scholar | |
|
Khojasteh A, Behnia H, Hosseini FS, Dehghan MM, Abbasnia P and Abbas FM: The effect of PCL-TCP scaffold loaded with mesenchymal stem cells on vertical bone augmentation in dog mandible: A preliminary report. J Biomed Mater Res B Appl Biomater. 101:848–854. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Mosekilde L, Weisbrode SE, Safron JA, Stills HF, Jankowsky ML, Ebert DC, Danielsen CC, Sogaard CH, Franks AF, Stevens ML, et al: Calcium-restricted ovariectomized Sinclair S-1 minipigs: An animal model of osteopenia and trabecular plate perforation. Bone. 14:379–382. 1993.PubMed/NCBI View Article : Google Scholar | |
|
Harper RA, Pfeiffer FM and Choma TJ: The minipig as a potential model for pedicle screw fixation: Morphometry and mechanics. J Orthop Surg Res. 14(246)2019.PubMed/NCBI View Article : Google Scholar | |
|
Bonucci E and Ballanti P: Osteoporosis-bone remodeling and animal models. Toxicol Pathol. 42:957–969. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Moest T, Koehler F, Prechtl C, Schmitt C, Watzek G and Schlegel KA: Bone formation in peri-implant defects grafted with microparticles: A pilot animal experimental study. J Clin Periodontol. 41:990–998. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Reichert JC, Saifzadeh S, Wullschleger ME, Epari DR, Schütz MA, Duda GN, Schell H, van Griensven M, Redl H and Hutmacher DW: The challenge of establishing preclinical models for segmental bone defect research. Biomaterials. 30:2149–2163. 2009.PubMed/NCBI View Article : Google Scholar | |
|
Schorn L, Sproll C, Ommerborn M, Naujoks C, Kübler NR and Depprich R: Vertical bone regeneration using rhBMP-2 and VEGF. Head Face Med. 13(11)2017.PubMed/NCBI View Article : Google Scholar | |
|
Moest T, Frabschka J, Kesting MR, Schmitt CM, Frohwitter G, Lutz R and Schlegel KA: Osseous ingrowth in allogeneic bone blocks applied for vertical bone augmentation: A preclinical randomised controlled study. Clin Oral Investig. 24:2867–2879. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Freilich M, Wen B, Shafer D, Schleier P, Dard M, Pendrys D, Ortiz D and Kuhn L: Implant-guided vertical bone growth in the mini-pig. Clin Oral Implants Res. 23:751–757. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Wen B, Shafer D, Schleier P, Pendrys D, Kuhn L and Freilich M: Implant-guided supracrestal alveolar bone growth using scaffolds, BMP-2, and novel scaffold-retaining device. Clin Oral Implants Res. 28:1411–1420. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Jinno Y, Jimbo R, Lindström M, Sawase T, Lilin T and Becktor JP: Vertical bone augmentation using ring technique with three different materials in the sheep mandible bone. Int J Oral Maxillofac Implants. 33:1057–1063. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Moussa M, Carrel JP, Scherrer S, Cattani-Lorente M, Wiskott A and Durual S: Medium-term function of a 3D printed TCP/HA structure as a new osteoconductive scaffold for vertical bone augmentation: A simulation by BMP-2 activation. Materials. 8:2174–2190. 2015. | |
|
Eitel F, Klapp F, Jacobson W and Schweiberer L: Bone regeneration in animals and in man. A contribution to understanding the relative value of animal experiments to human pathophysiology. Arch Orthop Trauma Surg. 99:59–64. 1981.PubMed/NCBI View Article : Google Scholar | |
|
Carrel JP, Wiskott A, Moussa M, Rieder P, Scherrer S and Durual S: A 3D printed TCP/HA structure as a new osteoconductive scaffold for vertical bone augmentation. Clin Oral Implants Res. 27:55–62. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Benlidayi ME, Tatli U, Salimov F, Tükel HC and Yüksel O: Comparison of autogenous and allograft bone rings in surgically created vertical bone defects around implants in a sheep model. Clin Oral Implants Res. 29:1155–1162. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Çolpak HA, Gönen ZB, Özdamar S, Alkan A and Kütük N: Vertical ridge augmentation using guided bone regeneration procedure and dental pulp derived mesenchymal stem cells with simultaneous dental implant placement: A histologic study in a sheep model. J Stomatol Oral Maxillofac Surg. 120:216–223. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Hurtig MB, Buschmann MD, Fortier LA, Hoemann CD, Hunziker EB, Jurvelin JS, Mainil-Varlet P, McIlwraith CW, Sah RL and Whiteside RA: Preclinical studies for cartilage repair: Recommendations from the international cartilage repair society. Cartilage. 2:137–152. 2011.PubMed/NCBI View Article : Google Scholar | |
|
Hoemann C, Kandel R, Roberts S, Saris DB, Creemers L, Mainil-Varlet P, Méthot S, Hollander AP and Buschmann MD: International cartilage repair society (ICRS) recommended guidelines for histological endpoints for cartilage repair studies in animal models and clinical trials. Cartilage. 2:153–172. 2011.PubMed/NCBI View Article : Google Scholar | |
|
Polo CI, Lima JL, De Lucca L, Piacezzi CB, Naclério-Homem Mda G, Arana-Chavez VE and Sendyk WR: Effect of recombinant human bone morphogenetic protein 2 associated with a variety of bone substitutes on vertical guided bone regeneration in rabbit calvarium. J Periodontol. 84:360–370. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Greenstein G, Greenstein B, Cavallaro J and Tarnow D: The role of bone decortication in enhancing the results of guided bone regeneration: A literature review. J Periodontol. 80:175–189. 2009.PubMed/NCBI View Article : Google Scholar | |
|
Kim DH, Cha JK, Song YW, Woo KM and Jung UW: Bone augmentation using small molecules with biodegradable calcium sulfate particles in a vertical onlay graft model in the rabbit calvarium. J Biomed Mater Res B Appl Biomater. 108:1343–1350. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Kim JW, Jung IH, Lee KI, Jung UW, Kim CS, Choi SH, Cho KS and Yun JH: Volumetric bone regenerative efficacy of biphasic calcium phosphate-collagen composite block loaded with rhBMP-2 in vertical bone augmentation model of a rabbit calvarium. J Biomed Mater Res A. 100:3304–3313. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Zere E, Einy S, Asbi T, Aizenbud Y, Gutmacher Z, Katzhandler E and Aizenbud D: Orthodontic extraction space closure with and without socket preservation: A comparative case analysis. Quintessence Int. 50:306–314. 2019.PubMed/NCBI View Article : Google Scholar |
