Open Access

New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review)

  • Authors:
    • Guoding Cao
    • Yuqi Pei
    • Peng Li
    • Peng Liu
    • Yapeng Deng
    • Yu Gao
    • Jun Liu
    • Xusheng Li
  • View Affiliations

  • Published online on: October 21, 2021     https://doi.org/10.3892/etm.2021.10906
  • Article Number: 1471
  • Copyright: © Cao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Osteoarthritis (OA) is a common disease of the elderly, posing a major personal and socioeconomic burden. OA is characterized by painful degeneration of articular cartilage, and its prevention, diagnosis and treatment remain problematic. Circular RNAs (circRNAs) constitute a large family of non‑coding RNAs that are widely distributed, stable, conserved and tissue‑specific. circRNAs have been found to be closely associated with OA development and progression, and they may serve as targets for disease prevention and treatment. The aim of the present article was to review the roles of circRNAs in OA and discuss possible treatment strategies.
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December-2021
Volume 22 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Cao G, Pei Y, Li P, Liu P, Deng Y, Gao Y, Liu J and Li X: New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review). Exp Ther Med 22: 1471, 2021.
APA
Cao, G., Pei, Y., Li, P., Liu, P., Deng, Y., Gao, Y. ... Li, X. (2021). New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review). Experimental and Therapeutic Medicine, 22, 1471. https://doi.org/10.3892/etm.2021.10906
MLA
Cao, G., Pei, Y., Li, P., Liu, P., Deng, Y., Gao, Y., Liu, J., Li, X."New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review)". Experimental and Therapeutic Medicine 22.6 (2021): 1471.
Chicago
Cao, G., Pei, Y., Li, P., Liu, P., Deng, Y., Gao, Y., Liu, J., Li, X."New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review)". Experimental and Therapeutic Medicine 22, no. 6 (2021): 1471. https://doi.org/10.3892/etm.2021.10906