Open Access

Cardiovascular comorbidities in psoriasis (Review)

  • Authors:
    • Daciana Elena Branisteanu
    • Alin Codrut Nicolescu
    • Daniel Constantin Branisteanu
    • Catalina Ioana Branisteanu
    • Andreea Corina Dragoi
    • Camelia Margareta Bogdanici
    • Mihaela Paula Toader
    • Andreea Lorena Tucaliuc
    • Andreea Dimitriu
    • Doru Daogaru
    • Ruxandra Angela Pirvulescu
    • Elena Andrese Porumb
  • View Affiliations

  • Published online on: December 17, 2021     https://doi.org/10.3892/etm.2021.11075
  • Article Number: 152
  • Copyright: © Branisteanu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Long considered a skin‑limited condition, psoriasis is currently defined as a chronic, immune‑mediated inflammatory disease, presenting, besides the skin changes, important systemic manifestations, the most common being: psoriatic arthritis, cardiovascular disease, metabolic syndrome, diabetes, inflammatory bowel disease and nonalcoholic steatohepatitis. It is a disease with a strong psycho‑emotional and social impact, both through skin changes such as pruritic, scaly erythematous plaques, and through the association of comorbidities that influence morbidity and mortality. It has been shown that psoriasis is an independent cardiovascular risk factor, with patients developing ischemic heart disease/acute coronary syndrome, hypertension, peripheral arterial disease, or stroke. The chronic inflammatory status of psoriasis and the production of specific cytokines may be the etiopathogenic link to atherosclerosis and cardiovascular disease. Biological therapy may affect atherosclerosis, leading to the arrest of the evolution or even regressing the changes in the atheromatous plaque. The aim of this review was to re‑evaluate the current knowledge regarding the cardiovascular comorbidities associated with psoriasis for optimal management of the patients.
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February-2022
Volume 23 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Branisteanu DE, Nicolescu AC, Branisteanu DC, Branisteanu CI, Dragoi AC, Bogdanici CM, Toader MP, Tucaliuc AL, Dimitriu A, Daogaru D, Daogaru D, et al: Cardiovascular comorbidities in psoriasis (Review). Exp Ther Med 23: 152, 2022.
APA
Branisteanu, D.E., Nicolescu, A.C., Branisteanu, D.C., Branisteanu, C.I., Dragoi, A.C., Bogdanici, C.M. ... Porumb, E.A. (2022). Cardiovascular comorbidities in psoriasis (Review). Experimental and Therapeutic Medicine, 23, 152. https://doi.org/10.3892/etm.2021.11075
MLA
Branisteanu, D. E., Nicolescu, A. C., Branisteanu, D. C., Branisteanu, C. I., Dragoi, A. C., Bogdanici, C. M., Toader, M. P., Tucaliuc, A. L., Dimitriu, A., Daogaru, D., Pirvulescu, R. A., Porumb, E. A."Cardiovascular comorbidities in psoriasis (Review)". Experimental and Therapeutic Medicine 23.2 (2022): 152.
Chicago
Branisteanu, D. E., Nicolescu, A. C., Branisteanu, D. C., Branisteanu, C. I., Dragoi, A. C., Bogdanici, C. M., Toader, M. P., Tucaliuc, A. L., Dimitriu, A., Daogaru, D., Pirvulescu, R. A., Porumb, E. A."Cardiovascular comorbidities in psoriasis (Review)". Experimental and Therapeutic Medicine 23, no. 2 (2022): 152. https://doi.org/10.3892/etm.2021.11075