Open Access

Artificial intelligence applications and robotic systems in Parkinson's disease (Review)

  • Authors:
    • Lacramioara Perju‑Dumbrava
    • Maria Barsan
    • Daniel Corneliu Leucuta
    • Luminita C. Popa
    • Cristina Pop
    • Nicoleta Tohanean
    • Stefan L. Popa
  • View Affiliations

  • Published online on: December 17, 2021     https://doi.org/10.3892/etm.2021.11076
  • Article Number: 153
  • Copyright: © Perju‑Dumbrava et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Parkinson's disease (PD) is the second most frequent neurodegenerative disorder following Alzheimer's disease. Advanced stages of PD, 4 or 5 of the Hoehn and Yahr Scale, are characterized by severe motor complications, limited mobility without assistance, risk of falling, and non‑motor complications. The aim of this review was to provide a practical overview on specific artificial intelligence (AI) systems for the management of advanced stages of PD, as well as relevant technological limitations. The authors conducted a systematic search on PubMed and EMBASE with predefined keywords searching for studies published until December 2020. Full articles that satisfied the inclusion criteria were included in the systematic review. To minimize results bias, the reference list was manually searched for pertinent articles to identify any additional relevant missed publications. Exclusion criteria included the following: Other stages of PD than 4 and 5 of the Hoehn and Yahr Scale, case reports, reviews, practice guidelines, commentaries, opinions, letters, editorials, short surveys, articles in press, conference abstracts, conference papers, and abstracts published without a full article. The search identified 21 studies analyzing AI‑based applications and robotic systems used for the management of advanced stages of PD, out of which 6 articles analyzed AI‑based applications for autonomous management of pharmacologic therapy, 5 articles analyzed home‑based telemedicine systems and 10 articles analysed robot‑assisted gait training systems. The authors identified significant evidence demonstrating that current AI‑based technologies are feasible for automatic management of patients with advanced stages of PD. Improving the quality of care and reducing the cost for patients and healthcare systems are the most important advantages.
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February-2022
Volume 23 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Perju‑Dumbrava L, Barsan M, Leucuta DC, Popa L, Pop C, Tohanean N and Popa S: Artificial intelligence applications and robotic systems in Parkinson's disease (Review). Exp Ther Med 23: 153, 2022.
APA
Perju‑Dumbrava, L., Barsan, M., Leucuta, D.C., Popa, L., Pop, C., Tohanean, N., & Popa, S. (2022). Artificial intelligence applications and robotic systems in Parkinson's disease (Review). Experimental and Therapeutic Medicine, 23, 153. https://doi.org/10.3892/etm.2021.11076
MLA
Perju‑Dumbrava, L., Barsan, M., Leucuta, D. C., Popa, L., Pop, C., Tohanean, N., Popa, S."Artificial intelligence applications and robotic systems in Parkinson's disease (Review)". Experimental and Therapeutic Medicine 23.2 (2022): 153.
Chicago
Perju‑Dumbrava, L., Barsan, M., Leucuta, D. C., Popa, L., Pop, C., Tohanean, N., Popa, S."Artificial intelligence applications and robotic systems in Parkinson's disease (Review)". Experimental and Therapeutic Medicine 23, no. 2 (2022): 153. https://doi.org/10.3892/etm.2021.11076