Good's syndrome with a relapsed bloodstream infection induced by <em>Alcaligenes</em> sp. after thymectomy: A case report

Chen,Sumei; Liu,Jiangfu; Lin,Yongnian; Gao,Yipeng

doi:10.3892/etm.2021.9830

Good's syndrome with a relapsed bloodstream infection induced by Alcaligenes sp. after thymectomy: A case report

Authors:
- Sumei Chen
- Jiangfu Liu
- Yongnian Lin
- Yipeng Gao
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Affiliations: Department of Infectious Diseases, The First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, Fujian 362000, P.R. China
Published online on: February 24, 2021 https://doi.org/10.3892/etm.2021.9830
Article Number: 399
Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Good's syndrome (GS) or thymoma‑associated immunodeficiency is a rare clinical syndrome with poor prognosis. The varied and unspecified clinical manifestations of GS commonly lead to a missed or delayed diagnosis. Thus, misdiagnosis and missed diagnosis are common. The present case study reports on a patient who suffered from a relapsed bloodstream infection caused by Alcaligenes sp. 6 months after thymectomy. The patient was finally diagnosed with GS after analyzing the clinical features and detecting T‑lymphocyte subsets in the peripheral blood and humoral immune function. The patient's condition improved after anti‑infection treatment and supplementation with intravenous immunoglobulin. Furthermore, no infection was observed during the 1‑year follow‑up.

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