Clinical and pathological studies of eight cases of lipidized fibrous histiocytoma
- Authors:
- Fangyun Liu
- Hongjun Wang
- Guoying Wu
- Congyang Li
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Affiliations: Fenlan Laboratory, Hangzhou, Zhejiang 310056, P.R. China, Department of Pathology, Yexian First People's Hospital, Pingdingshan, Henan 467200, P.R. China, Department of Pathology, People's Liberation Army 989 Hospital, Pingdingshan, Henan 467000, P.R. China
- Published online on: January 9, 2023 https://doi.org/10.3892/etm.2023.11792
-
Article Number:
93
-
Copyright: © Liu
et al. This is an open access article distributed under the
terms of Creative
Commons Attribution License.
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Abstract
Lipidized fibrous histiocytoma (FH) is a rare type of FH. The present study aimed to describe the clinical and pathological features of lipidized FH. A total of eight patients diagnosed with lipidized FH were retrospectively reviewed in the present study. The cohort included three male and five female patients (male to female ratio, 1.7:1) with a mean age of 48 years (range, 38‑62 years). In total, four tumors were located on the buttock, three on the lower leg and one on the forearm. Histological, lipidized FH showed a wide spectrum. Some cases included prominent stromal hyalinization and hyalinized vessels with scant lipid‑laden histiocytes. Other cases exhibited the prominent lipid‑laden histiocytes and scant stromal hyalinization. Overall, lipidized FH must be differentiated from other benign and malignant tumors, taking into account the therapeutic and prognostic differences between these different entities.
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