Open Access

Risk factors and survival analysis of haemodialysis complicated with infective endocarditis

  • Authors:
    • Ya-Jing He
    • Cun-Si Ye
    • Ke-Yang Xu
    • Li-Li Yang
    • Kai-Le Wang
    • Xiao-Mei Wang
    • Mei-Yu Li
    • Yu Wu
    • Qi-Su Ying
    • Ming Wang
    • Shi-Jian Quan
    • Xiu Yang
  • View Affiliations

  • Published online on: March 21, 2023     https://doi.org/10.3892/etm.2023.11902
  • Article Number: 203
  • Copyright: © He et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The clinical features and risk factors for survival time were analysed in haemodialysis patients complicated with infective endocarditis. A total of 101 infective endocarditis (IE) patients treated at Hangzhou First People's Hospital, from January 1, 2012, to April 1, 2022, were included in the present study. Baseline demographic data and laboratory data were collected for statistical analysis of risk factors and survival time in the IE with haemodialysis group (HD‑IE group, n=15) and the IE without haemodialysis group (NHD‑IE group, n=86). Haemoglobin, red blood cells, C‑reactive protein, procalcitonin, serum albumin, diabetes, invasive procedures, positive blood bacteria culture, heart valve calcification ratio, and left ventricular ejection fraction level were risk factors for infective endocarditis complicated with haemodialysis (P<0.05). Compared with the NHD‑IE group, the HD‑IE group had an obviously increased risk of mortality (χ2=6.323, P=0.012). The univariate Cox regression analysis showed that age, haemoglobin, red blood cells, serum albumin, left ventricular ejection score, longest vegetation diameter, combined hypotension and diabetes were risk factors for death; furthermore, multivariate Cox regression showed that age (HR=1.187, P=0.015), combined hypotension (HR=0.921, P=0.025) and the longest vegetation diameter (HR=9.191, P=0.004) were independent risk factors affecting the survival of patients. Collectively, the present study revealed that the mortality rate of HD‑IE patients was higher than that of NHD‑IE patients. Older age, hypotension, and the longest vegetation diameter were independent risk factors affecting the survival of patients. For HD‑IE patients, active and effective antibiotic treatment or surgical treatment should be strongly recommended.
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May-2023
Volume 25 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
He Y, Ye C, Xu K, Yang L, Wang K, Wang X, Li M, Wu Y, Ying Q, Wang M, Wang M, et al: Risk factors and survival analysis of haemodialysis complicated with infective endocarditis. Exp Ther Med 25: 203, 2023
APA
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X. ... Yang, X. (2023). Risk factors and survival analysis of haemodialysis complicated with infective endocarditis. Experimental and Therapeutic Medicine, 25, 203. https://doi.org/10.3892/etm.2023.11902
MLA
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X., Li, M., Wu, Y., Ying, Q., Wang, M., Quan, S., Yang, X."Risk factors and survival analysis of haemodialysis complicated with infective endocarditis". Experimental and Therapeutic Medicine 25.5 (2023): 203.
Chicago
He, Y., Ye, C., Xu, K., Yang, L., Wang, K., Wang, X., Li, M., Wu, Y., Ying, Q., Wang, M., Quan, S., Yang, X."Risk factors and survival analysis of haemodialysis complicated with infective endocarditis". Experimental and Therapeutic Medicine 25, no. 5 (2023): 203. https://doi.org/10.3892/etm.2023.11902