Antineutrophil cytoplasmic antibody‑associated vasculitis complicated with oral and maxillofacial space infection in a young woman: A case report

Qiao,Zhu; Zou,Yue; Liu,Shuangyan; Zhao,Hu; Li,Xiaodong

doi:10.3892/etm.2023.12043

Antineutrophil cytoplasmic antibody‑associated vasculitis complicated with oral and maxillofacial space infection in a young woman: A case report

Authors:
- Zhu Qiao
- Yue Zou
- Shuangyan Liu
- Hu Zhao
- Xiaodong Li
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Affiliations: Department of Stomatology II, Baoding No. 1 Central Hospital of Hebei Medical University, Baoding, Hebei 071000, P.R. China, Central Sterile Supply Department, Baoding No. 1 Central Hospital of Hebei Medical University, Baoding, Hebei 071000, P.R. China, Department of Internal Medicine, Graduate School of Hebei Medical University, Shijiazhuang, Hebei 050011, P.R. China, Department of Nephrology, Baoding No. 1 Central Hospital of Hebei Medical University, Baoding, Hebei 071000, P.R. China
Published online on: May 25, 2023 https://doi.org/10.3892/etm.2023.12043
Article Number: 344
Copyright: © Qiao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Antibody‑associated vasculitis (AAV) is a systemic autoimmune disease, with hormones and immunosuppressants as its main treatment measures. However, during the treatment process, various infections such as lung infections and urinary tract infections are prone to occur, and patients with OMSI are relatively rare. The present case report describes the case of a young woman who received long‑term oral glucocorticoids and immunosuppressive agents for the treatment of antineutrophil cytoplasmic (AAV). At hospital admission, the patient with a high fever and painful swelling of the left side of the mouth. The patient was diagnosed with an oral and maxillofacial space infection (OMSI). Therefore, the local incision, drainage and irrigation of abscesses were subsequently performed. Additionally, the immunosuppressive agents were discontinued, the glucocorticoid dose was reduced and intravenous antibiotic therapy was provided. The patient was discharged 1 week later in good condition. Notably, the incidence of AAV is extremely low. Although OMSI is not uncommon, the simultaneous occurrence of AAV in combination with OMSI has not been reported previously. To the best of our knowledge, this is the first reported case of AAV combined with OMSI.

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