Rare angiolymphoid hyperplasia with eosinophilia examined through fine needle aspiration cytology, histopathology and immunophenotypic characterization: A case report

Wang,Xiaohua; Shi,Xiang; Sun,Dahua; Wan,Meiping

doi:10.3892/etm.2023.12093

Rare angiolymphoid hyperplasia with eosinophilia examined through fine needle aspiration cytology, histopathology and immunophenotypic characterization: A case report

Authors:
- Xiaohua Wang
- Xiang Shi
- Dahua Sun
- Meiping Wan
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Affiliations: Department of Obstetrics, Qianjiang Central Hospital, Qianjiang, Hubei 433100, P.R. China, Department of Pathology, Qianjiang Central Hospital, Qianjiang, Hubei 433100, P.R. China, Department of Thyroid and Breast Surgery, Qianjiang Central Hospital, Qianjiang, Hubei 433100, P.R. China, Department of Traditional Chinese Medicine, Qianjiang Central Hospital, Qianjiang, Hubei 433100, P.R. China
Published online on: July 3, 2023 https://doi.org/10.3892/etm.2023.12093
Article Number: 394
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Angiolymphoid hyperplasia with eosinophilia (ALHE), a rare benign proliferative tumor, mainly occurs in several countries in Asia and it is characterized by true vascular branching hyperplasia with infiltration of a large number of lymphocytes and eosinophils in the stroma. The present case report analyzed the clinical symptoms and fine‑needle aspiration cytology, histopathological and immunohistochemical results of a patient with ALHE, and summarized the clinicopathological diagnostic features of the disease. To the best of our knowledge, this was the first study to comprehensively report the cytological, histopathological and immunophenotypic characteristics of ALHE, which could help clinicians fully understand this rare type of proliferative tumor.

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